• Bone matrix levels of Dickkopf and sclerostin are positively correlated with bone mass and strength in postmenopausal osteoporosis 

    Ueland, Thor; Stilgren, Lis; Bollerslev, Jens (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-03)
    Wnt signaling plays a pivotal role in maintaining bone mass. Secreted pathway modulators such as sclerostin (SOST) and Dickkopfs (DKKs) may influence bone mass inhibiting the canonical Wnt pathway. We evaluated whether bone protein content of secreted Wnt antagonists is related to age, bone mass, and strength in postmenopausal osteoporosis. We measured cortical and trabecular bone contents of SOST ...
  • Transkateter aorta ventil implantasjon. En retrospektiv kvalitetssikringsoppgave 

    Wilhelmsen, Håkon Wilhelm (Master thesis; Mastergradsoppgave, 2017-09-17)
    Bakgrunn: Aortastenose er en sykdom som har økt forekomst med økende alder, og alvorlig symptomgivende aortastenose har en dyster prognose. Uten behandling er median overlevelsestid 2 år dersom pasienten utvikler hjertesvikt. Tidligere ble denne pasientgruppen operert med åpen hjertekirurgi, men mange fikk ikke tilbud om behandling grunnet omfattende komorbiditet og høy-risiko. Dermed oppstod behovet ...
  • Drones and marine mammals in Svalbard 

    Palomino Gonzalez, Albert (Master thesis; Mastergradsoppgave, 2019-07-15)
    The impact of Remote Piloted Aircraft Systems (RPAS, or drones) on marine mammals remains poorly documented despite their increasing use by hobbyists and scientists. In the High-Arctic Archipelago of Svalbard, where marine mammals are facing increasing pressure from the coupled effects of climate modification and an expanding tourism industry, the use of RPAS remains largely unregulated to date. In ...
  • A patch of Calanus finmarchicus in the Lofoten-Vesterålen Region. Characteristics and determining factors 

    Santana Hernández, Néstor (Master thesis; Mastergradsoppgave, 2019-05-16)
    Zooplankton patchiness has been documented in many shelf areas and is of vital importance for understanding predator-prey relationships in pelagic marine systems. By combining hydrographic, acoustic and net data collected in spring 2017, we present a detailed understanding of the extent of this phenomenon in the Lofoten-Vesterålen region. Such patches are of potential interest not only for zooplankton ...
  • Impaired HDL function amplifies systemic inflammation in common variable immunodeficiency 

    Macpherson, Magnhild Eide; Halvorsen, Bente; Yndestad, Arne; Ueland, Thor; Mollnes, Tom Eirik; Berge, Rolf Kristian; Rashidi, Azita; Otterdal, Kari; Gregersen, Ida; Kong, Xiang Yi; Holven, Kirsten Bjørklund; Aukrust, Pål; Fevang, Børre; Jørgensen, Silje Fjellgård (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-01)
    Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency, characterized by inadequate antibody responses and recurrent bacterial infections. Paradoxically, a majority of CVID patients have non-infectious inflammatory and autoimmune complications, associated with systemic immune activation. Our aim was to explore if HDL, known to have anti-inflammatory properties, ...

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