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Impaired HDL function amplifies systemic inflammation in common variable immunodeficiency
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-01)
Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency, characterized by inadequate antibody responses and recurrent bacterial infections. Paradoxically, a majority of CVID patients have non-infectious inflammatory and autoimmune complications, associated with systemic immune activation. Our aim was to explore if HDL, known to have anti-inflammatory properties, ...