Background and objectives:<br>There are a range of mechanistic explanations on the formation and maintenance of delusions. Within the Bayesian brain hypothesis, particularly within the framework of predictive coding models, delusions are seen as an aberrant inference process characterized by either a failure in sensory attenuation or an aberrant weighting of prior experience. Testing of these ...

Estrogen receptors (ERs) are involved in sexual as well as non-sexual behaviors. In the present study we assessed the effects of stimuli inducing positive or negative affect on sociosexual, exploratory and fear-related behaviors of female rats housed in groups (4 females, 3 males) in a seminatural environment. Ovariectomized females were treated with oil, 17β‑estradiol benzoate (EB, 18 μg/kg), the ...

Transcranial direct current stimulation (tDCS) is a non‐invasive brain stimulation method that is frequently used to study cortical excitability changes and their impact on cognitive functions in humans. While most stimulators are capable of operating in double‐blind mode, the amount of discomfort experienced during tDCS may break blinding. Therefore, specifically designed sham stimulation protocols ...

Survey of workplace bullying in a Norwegian hospital found that 10% of nurses, therapists, and physicians (N=440) had witnessed bullying. Negative Acts Questionnaire (NAQ) scores were low, Minnesota Satisfaction Questionnaire (MSQ) scores were positive, and Organizational Commitment Questionnaire (OCQ) scores were neutral. NAQ scores and having witnessed bullying both predicted low MSQ scores, ...

This study aims to investigate the underlying neurobiological mechanisms that regulate natural reward seeking behaviors, specifically in the context of sexual behavior and sucrose self-administration. The role of CaMKIIa+neurons in the bed nucleus of the stria terminalis (BNST) was explored using chemogenetic silencing and -stimulation. Additionally, the study examined how these effects ...

The aim of this study was to investigate whether transcranial Direct Current Stimulation (tDCS) could improve verbal memory functions in healthy old and younger participants. We hypothesized that active tDCS led to significantly improved memory function, compared to placebo tDCS. Forty healthy participants (20 old and 20 younger participants) were included in the study. We applied a novel stimulation ...

<p><i>Rationale:</i> The place of case reports in the medical literature has been much debated in recent years. This study was undertaken to gain knowledge about the publication practice of case reports and case series from a major university hospital. <p><i>Method:</i> We decided to conduct a retrospective, bibliographic, descriptive study of published case reports and case series from a university ...

<i>Objective</i> - Reduction in cerebral volume is often found in underweight patients with anorexia nervosa (AN), but few studies have investigated other morphological measures. Cortical thickness (CTh) and surface area (CSA), often used to produce the measure of cortical volume, are developmentally distinct measures that may be differentially affected in AN, particularly in the developing brain. ...

Multiple cognitive domains, including learning, memory, and psychomotor speed, show significant reductions with age. Likewise, several cerebrospinal fluid (CSF) neurodegenerative biomarkers, including total tau (t-tau, a marker of neuronal body injury) and neurofilament light chain (NfL, a marker of axonal injury) show age-related increases in normal aging. In the current study, we aimed to investigate ...