• Altered functional connectivity in adolescent anorexia nervosa is related to age and cortical thickness 

      Myrvang, Anna Dahl; Vangberg, Torgil R.; Linnman, Clas; Stedal, Kristin; Rø, Øyvind; Endestad, Tor; Rosenvinge, Jan H.; Aslaksen, Per M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-06)
      Introduction - Functional networks develop throughout adolescence when anorexia nervosa (AN) normally debuts. In AN, cerebral structural alterations are found in most brain regions and may be related to the observed functional brain changes. Few studies have investigated the functional networks of the brain in adolescent AN patients.. The aim of this explorative study was to investigate multiple ...
    • Can accelerated transcranial direct current stimulation improve memory functions? An experimental, placebo-controlled study 

      Bystad, Martin; Storø, Benedicte Haug; Gundersen, Nina; Larsen Wiik, Ida Karine; Nordvang, Lene; Grønli, Ole; Rasmussen, Ingrid Daae; Aslaksen, Per M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-01)
      The aim of this study was to investigate whether transcranial Direct Current Stimulation (tDCS) could improve verbal memory functions in healthy old and younger participants. We hypothesized that active tDCS led to significantly improved memory function, compared to placebo tDCS. Forty healthy participants (20 old and 20 younger participants) were included in the study. We applied a novel stimulation ...
    • Cutoff criteria for the placebo response: a cluster and machine learning analysis of placebo analgesia. 

      Aslaksen, Per M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-28)
      Computations of placebo effects are essential in randomized controlled trials (RCTs) for separating the specific effects of treatments from unspecific effects associated with the therapeutic intervention. Thus, the identification of placebo responders is important for testing the efficacy of treatments and drugs. The present study uses data from an experimental study on placebo analgesia to suggest ...
    • Fear of diseases among people over 50 years of age : a survey 

      Bystad, Martin Kragnes; Grønli, Ole Kristian; Lilleeggen, Camilla; Aslaksen, Per M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-11)
      The aim of this study was to investigate the association between well-known diseases and fear of them in individuals over 50 years of age. Information on the fear of diseases can be relevant for both public health information purposes and clinical setting diagnostics. However, very few studies have investigated the fear of diseases in individuals over the age of 50. We used an electronic survey ...
    • Fear of pain potentiates nocebo hyperalgesia 

      Aslaksen, Per M.; Lyby, Peter Solvoll (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-12)
      Nocebo hyperalgesia has received sparse experimental attention compared to placebo analgesia. The aim of the present study was to investigate if personality traits and fear of pain could predict experimental nocebo hyperalgesia. One hundred and eleven healthy volunteers (76 females) participated in an experimental study in which personality traits and fear of pain were measured prior to induction ...
    • The Fear of Pain Questionnaire-III and the Fear of Pain Questionnaire-Short Form: a confirmatory factor analysis 

      Vambheim, Sara Magelssen; Lyby, Peter Solvoll; Aslaksen, Per M.; Flaten, Magne; Åsli, Ole; Martinussen, Laila Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-08)
      <i>Background</i>: The Fear of Pain Questionnaire-III (FPQ-III) is a widely used instrument to assess the fear of pain (FOP) in clinical and nonclinical samples. The FPQ-III has 30 items and is divided into three subscales: Severe Pain, Minor Pain and Medical Pain. Due to findings of poor fit of the original three-factor FPQ-III model, the Fear of Pain Questionnaire-Short Form ...
    • High-Definition Transcranial Direct Current Stimulation Improves Delayed Memory in Alzheimer’s Disease Patients: A Pilot Study Using Computational Modeling to Optimize Electrode Position 

      Rasmussen, Ingrid Daae; Boayue, Nya Mehnwolo; Mittner, Matthias; Bystad, Martin Kragnes; Grønli, Ole Kristian; Vangberg, Torgil Riise; Csifcsak, Gabor; Aslaksen, Per M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-14)
      Background: The optimal stimulation parameters when using transcranial direct current stimulation (tDCS) to improve memory performance in patients with Alzheimer’s disease (AD) are lacking. In healthy individuals, inter-individual differences in brain anatomy significantly influence current distribution during tDCS, an effect that might be aggravated by variations in cortical atrophy in AD ...
    • No effect of 2mA anodal tDCS over the M1 on performance and practice effect on Grooved Pegboard Test and Trail Making Test B 

      Fagerlund, Asbjørn Johansen; Freili, Janita; Danielsen, Therese; Aslaksen, Per M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-19)
      Previous studies suggest that transcranial direct current stimulation (tDCS) can facilitate motor performance and learning. In this double-blind experiment, 60 healthy human subjects (29 females) were randomized into three groups (active tDCS, sham tDCS, and no-treatment control group) in order to investigate the effect of a 20 min session of 2 mA tDCS over the motor cortex contralateral to the ...
    • Nocebo hyperalgesia and the startle response 

      Aslaksen, Per M.; Åsli, Ole; Øvervoll, Morten; BjØrkedal, espen (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-24)
      Background: The literature on the effects of nocebo on pain is sparse. The present experimental study investigated whether suggestions of nocebo hyperalgesia modified the startle response and whether increased startle contributed to the nocebo hyperalgesic effect. Methods: A design with four groups was employed; the participants were randomized into either a placebo group, a natural history group, ...
    • Non-linear heart rate variability as a discriminator of internalizing psychopathology and negative affect in children with internalizing problems and healthy controls 

      Fiskum, Charlotte; Andersen, Tonje Grønning; Bornas, Xavier; Aslaksen, Per M.; Flaten, Magne A.; Jacobsen, Karl (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-23)
      Background: Internalizing psychopathology and dysregulated negative affect are characterized by dysregulation in the autonomic nervous system and reduced heart rate variability (HRV) due to increases in sympathetic activity alongside reduced vagal tone. The neurovisceral system is however, a complex nonlinear system, and nonlinear indices related to psychopathology are so far less studied in children. ...
    • Transcranial direct current stimulation as a memory enhancer in patients with Alzheimer’s disease: a randomized, placebo-controlled trial 

      Bystad, Martin Kragnes; Grønli, Ole Kristian; Rasmussen, Ingrid Daae; Gundersen, Nina; Nordvang, Lene; Wang-Iversen, Henrik A.S.; Aslaksen, Per M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-23)
      <p><i>Background:</i> The purpose of this study was to assess the efficacy of transcranial direct current stimulation (tDCS) on verbal memory function in patients with Alzheimer’s disease. <p><i>Methods:</i> We conducted a randomized, placebo-controlled clinical trial in which tDCS was applied in six 30-minute sessions for 10 days. tDCS was delivered to the left temporal cortex with 2-mA intensity. ...