Browsing Prosjektoppgave forskerlinja i medisin by Issue Date

Now showing items 21-27 of 27

    • Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor 

      Lorentzen, Elias Myrvoll; Henriksen, Stian; Kaur, Amandeep; Kro, Grete Birkeland; Hammarström, Clara; Hirsch, Hans H; Midtvedt, Karsten; Rinaldo, Christine Hanssen (Journal article; Tidsskriftartikkel; Peer reviewed; Mastergradsoppgave; Master thesis, 2020-01-10)
      <i>Background</i> - BK Polyomavirus (BKPyV) causes premature graft failure in 1 to 15% of kidney transplant (KT) recipients. High-level BKPyV-viruria and BKPyV-DNAemia precede polyomavirus-associated nephropathy (PyVAN), and guide clinical management decisions. In most cases, BKPyV appears to come from the donor kidney, but data from biopsy-proven PyVAN cases are lacking. Here, we report the early ...

    • The effect of one-hour hypothermia on long term spatial memory in male Long Evans rats 

      Marsteen, Håvar (Master thesis; Mastergradsoppgave, 2020-11-01)
      The human body is willing to expend great amount of energy on mechanisms that keep the core temperature within a very small range. When these mechanisms are overwhelmed the body temperature either rises (hyperthermia) or drops (hypothermia). Hypothermia has earlier been used to induce retrograde amnesia (forgetting) and we have in this study examined if hypothermia can affect a robust long-term ...

    • Factors influencing mentors’ satisfaction: A study from medical schools in Norway and Canada 

      Skjevik, Elise Pauline; Schei, Edvin; Boudreau, J. Donald; Tjølsen, Arne; Ringberg, Unni; Fuks, Abraham; Kvernenes, Monika; Ofstad, Eirik H. (Master thesis; Mastergradsoppgave, 2020-11-01)
      <p><i>Phenomenon:</i> The mentoring of undergraduate medical students has been shown to benefit the mentors; however, detailed information on the factors that influence the satisfaction and motivation of mentors remains unclear. Such knowledge can be useful in sustaining group mentorship programs. The aim of this study was to investigate the experiences and perspectives of mentors to ascertain the ...

    • Challenges and objections to body temperature monitoring among pre-hospital personnel. A modified nominal group technique study. 

      Scott, Remi William (Mastergradsoppgave; Master thesis, 2021-11-01)
      Background: Hypothermia is common and correlates with mortality and morbidity for emergency patients, but a pre-hospital temperature measurement is often omitted. Objectives: To investigate barriers that pre-hospital care (PHC) providers experience with temperature monitoring, and solutions to the problem. Study design: Modified nominal group technique. Materials and methods: Fourteen PHC providers ...

    • Trends in prevalence of ultrasound-assessed carotid atherosclerosis in a general population over time. The Tromsø Study 1994-2016 

      Wang-Iversen, Rosa Elisabeth Theresia; Eltoft, Agnethe; Johnsen, Stein Harald; Mathiesen, Ellisiv B. (Master thesis; Mastergradsoppgave, 2021-11-11)
      <p><i>Background:</i> During the past decades, there has been a shift in risk factor levels in many high-income countries, with decrease in smoking, blood pressure and cholesterol levels, while body mass index, obesity and diabetes increase. The diverging trends may have opposite effects on prevalence of atherosclerosis. We aimed to assess carotid plaque prevalence and the association with risk ...

    • Recombinant T-cell receptors from HPA-1a specific T-cells 

      Sætre, Thomas (Mastergradsoppgave; Master thesis, 2022-02-01)
      Fetal- and neonatal alloimmune thrombocytopenia is a condition that can cause hemorrhage and potential brain damage or death in neonates. It is most often a result of maternal alloantibodies specific for fetal Human Platelet antigen 1a (HPA-1a) that destroy fetal platelets. The recognition of the HPA-1a peptide-MHC complex by T-cells involve a peculiar form of T-cell receptor peptide-MHC ...

    • Overexpression of miR-20a-5p in Tumor Epithelium Is an Independent Negative Prognostic Indicator in Prostate Cancer — A Multi-Institutional Study 

      Stoen, Maria J.; Andersen, Sigve; Rakaee, Mehrdad; Pedersen, Mona I.; Ingebriktsen, Lise M.; Donnem, Tom; Lombardi, Ana P. G.; Kilvaer, Thomas K.; Busund, Lill-Tove R.; Richardsen, Elin (Master thesis; Mastergradsoppgave; Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-26)
      <p><i>Background:</i> MicroRNAs (miRs) have critical regulatory roles in cell functions, and are involved in prostate cancer tumorigenesis. miR-20a-5p is a member of the oncogenic miR-17-92 cluster. Overexpressed miR-20a-5p has been shown to increase both cell proliferation and cell migration in cancers. The aim of our cohort study was to evaluate the prognostic role of miR-20a-5p in prostate cancer. ...