Blar i tittel Prosjektoppgave forskerlinja i medisin

Viser treff 28-31 av 31

    • Recombinant T-cell receptors from HPA-1a specific T-cells 

      Sætre, Thomas (Mastergradsoppgave; Master thesis, 2022-02-01)
      Fetal- and neonatal alloimmune thrombocytopenia is a condition that can cause hemorrhage and potential brain damage or death in neonates. It is most often a result of maternal alloantibodies specific for fetal Human Platelet antigen 1a (HPA-1a) that destroy fetal platelets. The recognition of the HPA-1a peptide-MHC complex by T-cells involve a peculiar form of T-cell receptor peptide-MHC ...

    • Serum free and bio-available 25-hydroxyvitamin D correlate better with bone density than serum total 25-hydroxyvitamin D 

      Johnsen, Martin Solvang (Master thesis; Mastergradsoppgave, 2015-10-29)
      Introduction/background In the circulation 25-hydroxyvitamin D (25(OH)D) is bound to vitamin D-binding protein (DBP) and albumin. Only a small fraction is in the unbound, free form. According to the ‘free-hormone-hypothesis’ only the free form is biologically active. Genetic differences in DBP may affect the binding to 25(OH)D and thereby the amount of free 25(OH)D. Methods In the present study ...

    • Treatment of Cardiovascular Dysfunction With PDE5-Inhibitors – Temperature Dependent Effects on Transport and Metabolism of cAMP and cGMP 

      Selli, Anders Lund (Master thesis; Mastergradsoppgave, 2023-10-21)
      Introduction: Cardiovascular dysfunction is a potentially lethal complication of hypothermia. Due to a knowledge gap, pharmacological interventions are not recommended at core temperatures below 30°C. Yet, further cooling is induced in surgical procedures and survival of accidental hypothermia is reported after rewarming from below 15°C, advocating a need for evidence-based treatment guidelines. In ...

    • Trends in prevalence of ultrasound-assessed carotid atherosclerosis in a general population over time. The Tromsø Study 1994-2016 

      Wang-Iversen, Rosa Elisabeth Theresia; Eltoft, Agnethe; Johnsen, Stein Harald; Mathiesen, Ellisiv B. (Master thesis; Mastergradsoppgave, 2021-11-11)
      <p><i>Background:</i> During the past decades, there has been a shift in risk factor levels in many high-income countries, with decrease in smoking, blood pressure and cholesterol levels, while body mass index, obesity and diabetes increase. The diverging trends may have opposite effects on prevalence of atherosclerosis. We aimed to assess carotid plaque prevalence and the association with risk ...