Now showing items 1-2 of 2
Estrogen receptors α and β and aromatase as independent predictors for prostate cancer outcome
(Master thesis; Mastergradsoppgave, 2016-10-11)
Androgens are considered important in normal prostate physiology and prostate cancer (PCa) pathogenesis. However, androgen-targeted treatment preventing PCa recurrence is still lacking. This indicates additional mediators contributing to cancer development. We sought to determine the prognostic significance of estrogen receptors, ERα and -β, and the aromatase enzyme in PCa. Tissue microarrays ...
Gender differences in hearts subjected to decreased NO-production and elevated blood pressure
(Master thesis; Mastergradsoppgave, 2016-10-31)
Hypertension is one of the most important risk factors for heart failure in the general population. Hypertensive heart failure is associated with heart failure with preserved ejection fraction (HFpEF). Women have an increase proportion of HFpEF compared to men. Endothelial dysfunction thereby reduced NO production is proposed to play an important role in the pathophysiology of HFpEF. A suggested ...