English
norskBlar i forfatter Artikler, rapporter og annet (Norges fiskerihøgskole) "Dahle, Maria"
Viser treff 1-10 av 10
-
Antiviral defense in salmonids – Mission made possible?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-30)Viral diseases represent one of the major threats for salmonid aquaculture. Survival from viral infections are highly dependent on host innate antiviral immune defense, where interferons are of crucial importance. Neutralizing antibodies and T cell effector mechanisms mediate long-term antiviral protection. Despite an immune cell repertoire comparable to higher vertebrates, farmed fish often fail ... -
Antiviral Responses and Biological Concequences of Piscine orthoreovirus Infection in Salmonid Erythrocytes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-16)Salmonid red blood cells are the main target cells for <i>Piscine orthoreovirus</i> (PRV). Three genotypes of PRV (PRV-1,2,3) infect Atlantic salmon (<i>Salmo salar</i>), Chinook salmon (<i>Onchorhynchus tshawytscha</i>), Coho salmon (<i>Oncorhynchus kisutch</i>), rainbow trout (<i>Onchorhynchus mykiss</i>) and brown trout (<i>Salmo trutta</i>), and can cause diseases like heart and skeletal muscle ... -
The Atlantic Salmon Gill Transcriptome Response in a Natural Outbreak of Salmon Gill Pox Virus Infection Reveals New Biomarkers of Gill Pathology and Suppression of Mucosal Defense
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-04)The salmon gill poxvirus (SGPV) is a large DNA virus that infects gill epithelial cells in Atlantic salmon and is associated with acute high mortality disease outbreaks in aquaculture. The pathological effects of SGPV infection include gill epithelial apoptosis in the acute phase of the disease and hyperplasia of gill epithelial cells in surviving fish, causing damage to the gill respiratory surface. ... -
Detection of specific Atlantic salmon antibodies against salmonid alphavirus using a bead-based immunoassay
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-30)Salmonid alphavirus (SAV) is the etiological cause of pancreas disease (PD) in Atlantic salmon (<i>Salmo salar</i>). Several vaccines against SAV are in use, but PD still cause significant mortality and concern in European aquaculture, raising the need for optimal tools to monitor SAV immunity. To monitor and control the distribution of PD in Norway, all salmonid farms are regularly screened for SAV ... -
Dissemination of Piscine orthoreovirus-1 (PRV-1) in Atlantic Salmon (Salmo salar) during the Early and Regenerating Phases of Infection
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-20)<i>Piscine orthoreovirus-1</i> (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (<i>Salmo salar</i>), but the line of events from infection, pathologic change, and regeneration has not been thoroughly described. In this study, the cellular localization and variation of PRV-1 RNA and protein levels were analyzed at different times post-exposure in experimentally ... -
First record of experimentally induced salmon gill poxvirus disease (SGPVD) in Atlantic salmon (Salmo salar L.)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-07)Salmon gill poxvirus (SGPV) infection is a common denominator in many cases of complex gill disease in the Norwegian salmon farming industry and may, as a single agent infection, result in salmon poxvirus disease (SGPVD). Experiences from the field suggest that stress may be a decisive factor for the induction of SGPVD. Here we investigated the effect of stress hormone treatment on SGPV kinetics and ... -
Fish Skin and Gill Mucus: A Source of Metabolites for Non-Invasive Health Monitoring and Research
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-31)Mucous membranes such as the gill and skin mucosa in fish protect them against a multitude of environmental factors. At the same time, changes in the molecular composition of mucus may provide valuable information about the interaction of the fish with their environment, as well as their health and welfare. In this study, the metabolite profiles of the plasma, skin and gill mucus of freshwater ... -
Genotyping of Salmon Gill Poxvirus Reveals One Main Predominant Lineage in Europe, Featuring Fjord- and Fish Farm-Specific Sub-Lineages
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-29)Salmon gill poxvirus (SGPV) can cause serious gill disease in Atlantic salmon (<i>Salmo salar</i> L.) and represents a significant problem to aquaculture industries in Northern Europe. Here, a single-tube multi-locus variable-number tandem-repeat (VNTR) analysis (MLVA) genotyping assay, targeting eight VNTR loci, was developed for studying the epizootiology of SGPV. Through MLVA typing of SGPV ... -
Piscine Orthoreovirus (PRV)-3, but Not PRV-2, Cross-Protects against PRV-1 and Heart and Skeletal Muscle Inflammation in Atlantic Salmon
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-06)Heart and skeletal muscle inflammation (HSMI), caused by infection with Piscine orthoreovirus-1 (PRV-1), is a common disease in farmed Atlantic salmon (Salmo salar). Both an inactivated whole virus vaccine and a DNA vaccine have previously been tested experimentally against HSMI and demonstrated to give partial but not full protection. To understand the mechanisms involved in protection against HSMI ... -
Røde blodceller - er de sensorer for laksens helsetilstand?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-11)Det er ikke tvil om at røde blodceller er livsviktige, siden de forsyner kroppen med oksygen, og laksens blodceller frakter oksygen kanskje enda mer effektivt enn våre blodceller gjør. Men det er ikke det eneste de røde blodcellene i laksen kan. De har en cellekjerne som kan uttrykke en mengde gener - de har sensorer for virus og stresshormoner og mye mer - og får signaler fra ...
