• Antioxidant and Anti-Inflammatory Activities in Extracts from Minke Whale (Balaenoptera acutorostrata) Blubber 

      Walquist, Mari; Stormo, Svein Kristian; Jensen, Ida-Johanne; Østerud, Bjarne; Eilertsen, Karl-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-08)
      Intake of long-chain omega-3 polyunsaturated fatty acids (LC-n3-PUFA) is commonly recognized to reduce cardiovascular disease (CVD). In previous studies, cold-pressed whale oil (CWO) and cod liver oil (CLO) were given as a dietary supplement to healthy volunteers. Even though CWO contains less than half the amount of LC-n3-PUFA of CLO, CWO supplement resulted in beneficial effects on anti-inflammatory ...
    • Antioxidant and Anti-Inflammatory Activities of Barettin 

      Lind, Karianne Fredenfeldt; Hansen, Espen; Østerud, Bjarne; Eilertsen, Karl-Erik; Bayer, Annette; Engqvist, Stig Olov Magnus; Leszczak, Kinga; Jørgensen, Trond Ø.; Andersen, Jeanette hammer (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      In this paper, we present novel bioactivity for barettin isolated from the marine sponge Geodia barretti. We found that barettin showed strong antioxidant activity in biochemical assays as well as in a lipid peroxidation cell assay. A de-brominated synthetic analogue of barettin did not show the same activity in the antioxidant cell assay, indicating that bromine is important for cellular activity. ...
    • Climate Performance, Environmental Toxins and Nutrient Density of the Underutilized Norwegian Orange-Footed Sea Cucumber (Cucumaria frondosa) 

      Langdal, Andreas; Eilertsen, Karl-Erik; Kjellevold, Marian; Heimstad, Eldbjørg Sofie; Jensen, Ida-Johanne; Elvevoll, Edel O. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-26)
      Low trophic species are often mentioned as additional food sources to achieve broader and more sustainable utilisation of the ocean. The aim of this study was to map the food potential of Norwegian orange-footed sea cucumber (Cucumaria frondosa). C. frondosa contained 7% protein, 1% lipids with a high proportion of polyunsaturated fatty acids, and a variety of micronutrients. The nutrient density ...
    • Cold-pressed minke whale oil reduces circulating LDL/VLDL-cholesterol, lipid oxidation and atherogenesis in apolipoprotein E-deficient mice fed a Western-type diet for 13 weeks 

      Walquist, Mari; Stormo, Svein Kristian; Østerud, Bjarne; Elvevoll, Edel Oddny; Eilertsen, Karl-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-04)
      Background<br> Long-chain n3-polyunsaturated fatty acids (LC n3-PUFA) are well known for their anti-inflammatory activity and their impact on cardiovascular disease. Cold-pressed whale oil (CWO) has half the amount of LC n3-PUFA compared to cod liver oil (CLO). Still, there has been observed more pronounced beneficial effects on cardiovascular disease markers from intake of CWO compared to intake ...
    • Dietary enrichment of apolipoprotein E-deficient mice with extra virgin olive oil in combination with seal oil inhibits atherogenesis 

      Cludts, Katrien; Eilertsen, Karl-Erik; Mæhre, Hanne K; Hoylaerts, Marc; Olsen, Jan Ole (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
    • Dietary intake of cod and scallop reduces atherosclerotic burden in female apolipoprotein E-deficient mice fed a Western-type high fat diet for 13 weeks 

      Jensen, Ida-Johanne; Walquist, Mari; Liaset, Bjørn; Elvevoll, Edel Oddny; Eilertsen, Karl-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-02)
      <b>Background:</b> It is now increasingly recognized that the beneficial effects of seafood consumption is not limited to lipids and fatty acid, but that the protein part, i.e., peptides and amino acids, together with vitamins and even unknown bioactive constituents also are important for disease prevention. This study was designed to evaluate the putative anti-atherogenic effects of different ...
    • Effects of similar intakes of marine n-3 fatty acids from enriched food products and fish oil on cardiovascular risk markers in healthy human subjects 

      Kirkhus, Bente; Lamglait, Amandine; Eilertsen, Karl-Erik; Falch, Eva; Haider, Trond; Vik, Hogne; Hoem, Nils; Hagve, Tor-Arne; Basu, Samar; Olsen, Elisabeth; Seljeflot, Ingebjørg; Nyberg, Lena; Elind, Elisabeth; Ulven, Stine Marie (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      There is convincing evidence that consumption of fish and fish oil rich in long-chain (LC) n-3 PUFA (n-3 LCPUFA), EPA (20 : 5n-3) and DHA (22 : 6n-3) reduce the risk of CHD. The aim of the present study was to investigate whether n-3 LCPUFA-enriched food products provide similar beneficial effects as fish oil with regard to incorporation into plasma lipids and effects on cardiovascular risk markers. ...
    • Enzymatic pre-treatment increases the protein bioaccessibility and extractability in dulse (Palmaria palmata) 

      Mæhre, Hanne K; Jensen, Ida-Johanne; Eilertsen, Karl-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-26)
      Several common protein extraction protocols have been applied on seaweeds, but extraction yields have been limited. The aims of this study were to further develop and optimize existing extraction protocols and to examine the effect of enzymatic pre-treatment on bioaccessibility and extractability of seaweed proteins. Enzymatic pre-treatment of seaweed samples resulted in a three-fold increase ...
    • Fatty Acid Composition of the Lipids from Atlantic Salmon—Comparison of Two Extraction Methods without Halogenated Solvents 

      Nechev, Jordan; Edvinsen, Guro Kristine; Eilertsen, Karl-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-01)
      The scope of this paper was to apply two recently developed methods for lipid extraction: the methyl tert-butyl ether (MTBE) method and the BUME method. These two methods do not include halogenated solvents, which makes them less hazardous to the environment, less toxic, and needed in less volume compared to the standard methods for lipid extraction. Fatty acid composition of the lipids from Atlantic ...
    • Heat treatment increases the protein bioaccessibility in the red seaweed dulse (Palmaria palmata), but not in the brown seaweed winged kelp (Alaria esculenta) 

      Mæhre, Hanne K; Edvinsen, Guro Kristine; Eilertsen, Karl-Erik; Elvevoll, Edel Oddny (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-25)
      Bioaccessibility of plant proteins has been shown to be inferior to that of proteins of animal origin. Heat treatment has been shown to positively affect this in some plants. The aim of this study was to investigate the effect of heat treatment on bioaccessibility of seaweed proteins. An in vitro gastrointestinal digestion model was used for evaluation of potential effects on the brown seaweed Alaria ...
    • Inclusion of photoautotrophic cultivated diatom biomass in salmon feed can deter lice 

      Eilertsen, Hans Christian; Elvevoll, Edel O.; Giæver, Ingeborg Hulda; Svenning, Jon Brage; Dalheim, Lars; Svalheim, Ragnhild Aven; Vang, Birthe; Siikavuopio, Sten Ivar; Dragøy, Ragnhild; Ingebrigtsen, Richard Andre; Hansen, Espen Holst; Hustad, Anette; Eilertsen, Karl-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-29)
      The aim of this study was to evaluate the potential of diatom (microalgae) biomass as a lice-reducing ingredient in salmon feed. The original hypothesis was based on the fact that polyunsaturated aldehydes (PUAs), e.g. 2-trans, 4-trans decadenial (A3) produced by diatoms can function as grazing deterrents and harm copepod development. Salmon lice (Lepeophtheirus salmonis) is a copepod, and we intended ...
    • Mass Cultivation of Microalgae: I. Experiences with Vertical Column Airlift Photobioreactors, Diatoms and CO2 Sequestration 

      Eilertsen, Hans Christian; Eriksen, Gunilla; Bergum, John-Steinar; Strømholt, Jo; Elvevoll, Edel O.; Eilertsen, Karl-Erik; Heimstad, Eldbjørg Sofie; Giæver, Ingeborg Hulda; Israelsen, Linn; Svenning, Jon Brage; Dalheim, Lars; Osvik, Renate Døving; Hansen, Espen Holst; Ingebrigtsen, Richard Andre; Aspen, Terje M; Wintervoll, Geir-Henning (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-17)
      From 2015 to 2021, we optimized mass cultivation of diatoms in our own developed vertical column airlift photobioreactors using natural and artificial light (LEDs). The project took place at the ferrosilicon producer Finnfjord AS in North Norway as a joint venture with UiT—The Arctic University of Norway. Small (0.1–6–14 m<sup>3</sup>) reactors were used for initial experiments and to produce inoculum ...
    • New marine low trophic resources as food: nutritional and food safety aspects 

      Elvevoll, Edel Oddny; Eilertsen, Karl-Erik; Aschan, Michaela Maria; Bandarra, Narcissa (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-01)
      Food agencies recommend increasing the consumption of aquatic food to promote healthy living and sustainability, and, particularly, to prevent Western lifestyle-related diseases and secure sustainable food systems. This requires growth in global seafood production, and the utilization of low trophic species (LTS) is suggested. LTS are already considered nutritious and important in Asian and ...
    • Omega-3 Fatty Acids and Cardiovascular Diseases: Effects, Mechanisms and Dietary Relevance 

      Mæhre, Hanne K; Jensen, Ida-Johanne; Elvevoll, Edel Oddny; Eilertsen, Karl-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-18)
      ω-3 fatty acids (n-3 FA) have, since the 1970s, been associated with beneficial health effects. They are, however, prone to lipid peroxidation due to their many double bonds. Lipid peroxidation is a process that may lead to increased oxidative stress, a condition associated with adverse health effects. Recently, conflicting evidence regarding the health benefits of intake of n-3 from seafood or ...
    • Possible Health Effects of a Wax Ester Rich Marine Oil 

      Schots, Pauke C.; Pedersen, Alice Marie; Eilertsen, Karl-Erik; Olsen, Ragnar Ludvig; Larsen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-26)
      The consumption of seafood and the use of fish oil for the production of nutraceuticals and fish feed have increased over the past decades due the high content of long-chain polyunsaturated omega-3 fatty acids. This increase has put pressure on the sustainability of fisheries. One way to overcome the limited supply of fish oil is to harvest lower in the marine food web. <i>Calanus finmarchicus</i>, ...
    • Prosessering av sjømat – Endring i næringsinnhold, biotilgjengelighet og helseeffekter 

      Larsen, Rune; Stormo, Svein Kristian; Eilertsen, Karl-Erik; Mæhre, Hanne K; Jensen, Ida-Johanne; Østerud, Bjarne; Elvevoll, Edel Oddny (Research report; Forskningsrapport, 2010-11-29)
      Rapporten oppsummerer hvordan prosessering kan påvirke innholdet av næringsstoffer i sjømat, samt hvordan biotilgjengeligheten til ulike stoffer kan endres som følge av prosessbetingelsene. I tillegg er det kort redegjort for vitenskapelig status på helseeffektene av sjømatkonsum, samt hvilke ernæringsmessige faktorer som gjør sjømat til et særegent næringsmiddel. Økt prosesseringsgrad av sjømat ...
    • An Update on the Content of Fatty Acids, Dioxins, PCBs and Heavy Metals in Farmed, Escaped and Wild Atlantic Salmon (Salmo salar L.) in Norway 

      Jensen, Ida-Johanne; Eilertsen, Karl-Erik; Otnæs, Carina Helen Almli; Mæhre, Hanne K; Elvevoll, Edel O. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-19)
      In this paper, we present updated data on proximate composition, amino acid, and fatty acid composition, as well as concentrations of dioxins, polychlorinated biphenyls (PCBs), and selected heavy metals, in fillets from farmed (n = 20), escaped (n = 17), and wild (n = 23) Atlantic salmon (<i>Salmo salar</i> L.). The concentrations of dioxins (0.53 ± 0.12 pg toxic equivalents (TEQ)/g), dioxin-like ...