• Structure-activity relationships of the antimicrobial peptide arasin 1 - and mode of action studies of the N terminal, proline-rich region 

      Paulsen, Victoria; Blencke, Hans-Matti; Benincasa, Monica; Haug, Tor; Eksteen, Jacobus Johannes; Styrvold, Olaf B.; Scocchi, Marco; Stensvåg, Klara (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Arasin 1 is a 37 amino acid long proline-rich antimicrobial peptide isolated from the spider crab, Hyas araneus. In this work the active region of arasin 1 was identified through structure-activity studies using different peptide fragments derived from the arasin 1 sequence. The pharmacophore was found to be located in the proline/arginine-rich NH2 terminus of the peptide and the fragment arasin ...