• IPNV with high and low virulence: host immune responses and viral mutations during infection 

      Skjesol, Astrid; SkjÆveland, ingrid; Elnæs, Marianne; Timmerhaus, Gerrit Frantz; Fredriksen, Børge Nilsen; Jørgensen, Sven Martin; Krasnov, Aleksei; Jørgensen, Jorunn B (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Infectious pancreatic necrosis virus (IPNV) is an aquatic member of the Birnaviridae family that causes widespread disease in salmonids. IPNV is represented by multiple strains with markedly different virulence. Comparison of isolates reveals hyper variable regions (HVR), which are presumably associated with pathogenicity. However little is known about the rates and modes of sequence divergence and ...