• Possible Health Effects of a Wax Ester Rich Marine Oil 

      Schots, Pauke C.; Pedersen, Alice Marie; Eilertsen, Karl-Erik; Olsen, Ragnar Ludvig; Larsen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-26)
      The consumption of seafood and the use of fish oil for the production of nutraceuticals and fish feed have increased over the past decades due the high content of long-chain polyunsaturated omega-3 fatty acids. This increase has put pressure on the sustainability of fisheries. One way to overcome the limited supply of fish oil is to harvest lower in the marine food web. <i>Calanus finmarchicus</i>, ...
    • Two Isomeric C16 Oxo-Fatty Acids from the Diatom Chaetoceros karianus Show Dual Agonist Activity towards Human Peroxisome Proliferator-Activated Receptors (PPARs) α/γ 

      Moldes-Anaya, Angel; Sæther, Thomas; Uhlig, Silvio; Nebb, Hilde Irene; Larsen, Terje; Eilertsen, Hans Christian; Paulsen, Steinar Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-25)
      The peroxisome proliferator-activated receptors (PPARs) function as ligand-activated transcription factors that convert signals in the form of lipids to physiological responses through the activation of metabolic target genes. Due to their key roles in lipid and carbohydrate metabolism, the PPARs are important drug targets. However, for several of the PPAR drugs currently in use, adverse side effects ...