Blar i forfatter Artikler, rapporter og annet (Norges fiskerihøgskole) "Seternes, Tore"

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    • Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) 

      Seternes, Tore; Poppe, Trygve T; Bøgwald, Jarl; Lynghammar, Arve; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-28)
      The scavenger endothelial cells (SECs) of vertebrates are an important class of endocytic cells responsible for clearance of foreign and physiological waste macromolecules, partitioning in the immune system, functioning as a cellular powerplant by producing high energy metabolites like lactate and acetate. All animal phyla possess SECs, but the tissue localization of SECs has only been investigated ...

    • Cleaner fish in aquaculture: review on diseases and vaccination 

      Erkinharju, Toni; Dalmo, Roy Ambli; Hansen, Miroslava; Seternes, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-26)
      Combating and controlling sea lice causes large economic costs for the farmers, with estimated values of more than 305 million euros (€) per year. Increased resistance against traditional chemotherapeutants due to evolutionary drivers in the sea lice combined with the lack of an effective vaccine and few other chemical treatments available are expected to cause these costs to increase. Several ...

    • Differences in smolt status affect the resistance of Atlantic salmon (Salmo salar L.) against infectious pancreatic necrosis, while vaccine-mediated protection is unaffected 

      Jensen, Ingvill; Overrein, Mathias; Fredriksen, Børge Nilsen; Strandskog, Guro; Seternes, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-18)
      In today's aquaculture of Atlantic salmon (<i>Salmo salar</i> L.), a majority of viral disease outbreaks occur after seawater transfer. A relevant question is how the parr–smolt transformation influences the efficacy of viral vaccines and the innate resistance against viral diseases. In this study, vaccinated and unvaccinated A. salmon parr were exposed to different photoperiodic regimens (1‐, 3‐ ...

    • Evaluation of histological post-mortem changes in farmed Atlantic salmon (Salmo salar L.) at different time intervals and storage temperatures 

      Furnesvik, Lisa; Erkinharju, Toni; Hansen, Miroslava; Yousaf, Muhammad Naveed; Seternes, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-29)
      The aim of this study was to evaluate histologic post-mortem autolytic changes in farmed Atlantic salmon. The fish were either stored at room temperature (RT, 21°C), refrigerated (4°C) or frozen (−20°C), while fish necropsy was performed at 0, 1, 4, 24 and 48 h post-storage (hps). In addition, gills were sampled at 0, 5, 10, 15, 30 and 45 min post-storage (mps) at room temperature (RT). The haematoxylin ...

    • Long-term welfare effects of repeated warm water treatments on Atlantic salmon (Salmo salar) 

      Moltumyr, Lene; Nilsson, Jonatan; Madaro, Angelico; Seternes, Tore; Rønnestad, Ivar; Stien, Lars Helge (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-30)
      Warm water treatment has in recent years become widely used for ridding salmonids of sea lice in aquaculture although the consequences of the treatment for fish welfare are not adequately investigated. The objective of this study was to document potential long-term welfare effects of repeated warm water treatments on Atlantic salmon (Salmo salar). Five weeks after a baseline welfare indicator ...

    • A plant 35S CaMV promoter induces long-term expression of luciferase in Atlantic salmon 

      Seternes, Tore; Tonheim, Tom Christian; Myhr, Anne Ingeborg; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2016)
      The long-term persistence and activity of a naked plasmid DNA (pGL3-35S) containing a luc gene (reporter gene) controlled by a plant 35S CaMV promoter was studied in Atlantic salmon (Salmo salar L.) after injection. Atlantic salmon (mean weight 70 grams) were injected intramuscularly with 100 μg of plasmid DNA. Blood, different tissues and organs were sampled at different time points up to day 535 ...

    • The Relative Bioavailability of Ibuprofen After Administration With a Novel Soft Chewable Drug Formulation 

      Hattrem, Magnus Nergård; Dille, Morten Johnsen; Seternes, Tore; Ege, Thorfinn; Draget, Kurt Ingar (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-25)
      The first aim of the present study was to evaluate the bioavailability of ibuprofen dispersed in a novel soft chewable formulation compared with a traditional ibuprofen tablet; its second was to map the quality of taste masking and patient product satisfaction. In a phase 1, single-center, open-label, randomized, crossover study, healthy subjects received a softchew formulation or a hard tablet ...

    • Scavenger endothelial cells of fish, a review 

      Seternes, Tore; Bøgwald, Jarl; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-17)
      The definition of scavenger endothelial cells (SEC) is exclusively based on functional and structural characteristics. The following characteristics are common hallmarks for the vertebrate SEC: (a) All vertebrates examined are furnished with a population of special SEC that plays a role in the catabolism of physiologic and non-physiologic soluble waste macromolecules. (b) From the ligands that are ...

    • Studies on the antibody response and side effects after intramuscular and intraperitoneal injection of Atlantic lumpfish (Cyclopterus lumpus L.) with different oil-based vaccines 

      Erkinharju, Toni; Lundberg, Martin, Rønbeck; Isdal, Eivind; Hordvik, Ivar; Dalmo, Roy Ambli; Seternes, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-26)
      Atlantic lumpfish (<i>Cyclopterus lumpus</i> L.) is used as a biological delousing agent for sea lice (<i>Lepeophtheirus salmonis</i> K.) infestations in Norwegian aquaculture. Here, we present a study on the antibody response and vaccine side effects after intramuscular and intraperitoneal injection of lumpfish with two vaccines. Both vaccines contained bacterial antigens from atypical <i>Aeromonas ...

    • Studies on the effects of LPS, ß‐glucan and metabolic inhibitors on the respiratory burst and gene expression in Atlantic salmon macrophages 

      Ulvestad, Johanne Skår; Kumari, Jaya; Seternes, Tore; Chi, Heng; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-30)
      Reactive oxygen species (ROS) production in macrophage‐like cells is induced as an antimicrobial defence against invading pathogens. In this study, we have explored how different stimuli and metabolic inhibitors affect the level of respiratory burst in Atlantic salmon (<i>Salmo salar</i> L.) head kidney macrophage‐like cells. Cells stimulated in vitro by bacterial lipopolysaccharide (LPS) and ß‐glucan ...

    • Thee level of eicosapentaenoic (EPA),but not docosahexaenoic acid (DHA) is related to formulation and concentration of EPA and DHA in feed 

      Seternes, Tore; Johansson, Gunhild S.; Evje, Iselin; Olsen, Ragnar Ludvig (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-22)
      The present study investigated how the concentration of PUFA in blood and muscle of Atlantic salmon (<i>Salmo salar</i> L.) changed when fed 4 diets containing very different amounts of LC-PUFA in fresh water for 84 days. The n-3 LC-PUFA constituted 4.4, 24.2, 18.4, and 51.5% of the total fatty acids in the diets made with rapeseed oil, anchoveta oil, a combination of rapeseed oil (60%) and anchoveta ...

    • Vaccination of Atlantic lumpfish (Cyclopterus lumpus L.) at a low temperature leads to a low antibody response against Aeromonas salmonicida 

      Erkinharju, Toni; Dalmo, Roy Ambli; Vågsnes, Øyvind; Hordvik, Ivar; Seternes, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-11)
      We present a study on the effect of water temperature on immunization of Atlantic lumpfish. In total, 360 fish were vaccinated with either 50 μl of an oil‐based injection vaccine (VAX), with Aeromonas salmonicida and Vibrio salmonicida antigens, or PBS. Fish were vaccinated at three different water temperatures, 5°C, 10°C and 15°C, and sorted into six groups (N = 60). Lumpfish were weighed every 3 ...