• Peptide from sea anemone metridium senile affects transient receptor potential ankyrin-repeat 1 (TRPA1) function and produces analgesic effect 

      Logashina, Yulia A.; Mosharova, Irina V.; Korolkova, Yulia V.; Shelukhina, Irina V; Dyachenko, Igor A.; Palikov, Victor A.; Palikova, Yulia A.; Murashev, Arkadii N.; Kozlov, Sergey A.; Stensvåg, Klara; Andreev, Yaroslav A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-11)
      The Transient Receptor Potential Ankyrin-repeat 1 (TRPA1) is an important player in pain and inflammatory pathways. It is a promising target for novel drugs development for treatment of a number of pathological states. A novel peptide producing significant potentiating effect (up to ~90%) on AITC- and diclofenac-induced currents of TRPA1 was isolated from the venom of sea anemone <i>Metridium ...