Show simple item record

dc.contributor.authorPadros, Francesc
dc.contributor.authorKnudsen, Rune
dc.contributor.authorBlasco-Costa, Isabel
dc.date.accessioned2018-08-13T13:35:07Z
dc.date.available2018-08-13T13:35:07Z
dc.date.issued2018
dc.description.abstractThe eye represents an immune privileged organ where parasites can escape host reactions. This study provides the first systematic evidence of the pathology associated with <i>Diplostomum</i> sp. infection in the eye retina of fish (i.e. Arctic charr). Histological sections showed that the trematodes caused mechanical disengagement between the retinal pigmentary epithelium and the neurosensory retina, with damaged cones and rods in the outer segment and epithelium reduced to a single layer of pigmentary cells. The metacercariae were “floating” in possibly fluid-filled vesicles together with several round cells, mostly located in the anterio-dorsal and anterio-ventral areas of the eye near the iris. The round cells may indicate internal retinal damage repair mechanisms, without connections to the general immune system. Metacercariae intestines contained pigmented cellular debris indicating that they feed on retinal epithelium. These retinal lesions may have similar vision effects as focal retinal detachment in vertebrates. <i>Diplostomum</i> metacercaria alters fish visual acuity but may in a lesser degree lead to a severe or total visual impairment because of repairing mechanisms. The pathology in the retina seems thereby to be dependent on fish size, age and dose.en_US
dc.description.sponsorshipNatural History Museum of Geneva Swiss National Science Foundationen_US
dc.descriptionSource at <a href=https://doi.org/10.1016/j.ijppaw.2018.01.007> https://doi.org/10.1016/j.ijppaw.2018.01.007</a>. Accepted manuscript version, licensed <a href=http://creativecommons.org/licenses/by-nc-nd/4.0/> CC BY-NC-ND 4.0.</a>en_US
dc.identifier.citationPadrós, F., Knudsen, R. & Blasco-Costa, I. (2018). Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes: Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus. International Journal for Parasitology: Parasites and Wildlife, 7(1), 68-74. https://doi.org/10.1016/j.ijppaw.2018.01.007en_US
dc.identifier.cristinIDFRIDAID 1570356
dc.identifier.doi10.1016/j.ijppaw.2018.01.007
dc.identifier.issn2213-2244
dc.identifier.urihttps://hdl.handle.net/10037/13387
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalInternational Journal for Parasitology: Parasites and Wildlife
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Matematikk og Naturvitenskap: 400::Zoologiske og botaniske fag: 480::Parasittologi: 484en_US
dc.subjectVDP::Mathematics and natural science: 400::Zoology and botany: 480::Parasitology: 484en_US
dc.subjectHelminthsen_US
dc.subjectEyeflukesen_US
dc.subjectRetinaen_US
dc.subjectPathologyen_US
dc.subjectSalmonidaeen_US
dc.subjectFreshwateren_US
dc.titleHistopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes: Trematoda) infection in polymorphic Arctic charr Salvelinus alpinusen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


File(s) in this item

Thumbnail

This item appears in the following collection(s)

Show simple item record