Blar i tittel Artikler, rapporter og annet (farmasi)

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    • The Vaginal-PVPA: A Vaginal Mucosa-Mimicking In Vitro Permeation Tool for Evaluation of Mucoadhesive Formulations 

      Falavigna, Margherita; Pattacini, Martina; Wibel, Richard; Sonvico, Fabio; Skalko-Basnet, Natasa; Flaten, Gøril Eide (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-19)
      Drug administration to the vaginal site has gained increasing attention in past decades, highlighting the need for reliable in vitro methods to assess the performance of novel formulations. To optimize formulations destined for the vaginal site, it is important to evaluate the drug retention within the vagina as well as its permeation across the mucosa, particularly in the presence of vaginal fluids. ...

    • vCOMBAT: a novel tool to create and visualize a computational model of bacterial antibiotic target-binding 

      Tran, Vi Ngoc-Nha; Shams, Alireza; Ascioglu, Sinan; Martinecz, Antal; Liang, Jingyi; Clarelli, Fabrizio; Mostowy, Rafal; Cohen, Ted; Abel zur Wiesch, Pia (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-06)
      Background: As antibiotic resistance creates a signifcant global health threat, we need not only to accelerate the development of novel antibiotics but also to develop better treatment strategies using existing drugs to improve their efcacy and prevent the selection of further resistance. We require new tools to rationally design dosing regimens from data collected in early phases of antibiotic ...

    • Veitrafikkulykker knyttet til forskrivning av legemidler : En registerbasert kohortstudie 

      Skurtveit, Svetlana; Engeland, Anders; Bramness, Jørgen G.; Mørland, Jørg (Journal article; Tidsskriftartikkel; Peer reviewed, 2008)

    • Vurdering av publikasjonen: “Long term toxicity of a Roundup herbicide and a Rounduptolerant genetically modified maize” (Séralini et al. (2012), Food Chem Toxicol 50*). Uttalelse fra Faggruppen for genmodifiserte organismer i Vitenskapskomiteen for mattrygghet 

      Nerland, Audun Helge; Bakke, Anne Marie; Bernhoft, Aksel; Rivedal, Edgar; Torp, Torfinn; Brandtzæg, Per; Holck, Askild Lorentz; Junttila, Olavi; Konestabo, Heidi Sjursen; Meadow, Richard; Mikalsen, Arne; Nielsen, Kaare Magne; Sipinen, Ville Erling; Sorteberg, Hilde-Gunn Opsahl; Vikse, Rose; Andreassen, Åshild Kristine (Research report; Forskningsrapport, 2012-12-20)
      Den 19. september 2012 ble det publisert en artikkel i det tyske tidsskriftet «Food and Chemical Toxicology» som vakte oppmerksomhet i store deler av verden. Artikkelen bygger på en toårig fôringsstudie med rotter og konkluderer med en antatt økt hyppighet for ulike svulstdannelser og nyrelidelser blant dyrene knyttet til den genmodifiserte maisen NK603 og plantevernmidlet Roundup som inneholder ...

    • What do Australian consumers, pharmacists and prescribers think about documenting indications on prescriptions and dispensed medicines labels?: A qualitative study 

      Garada, Mona; McLachlan, Andrew J; Schiff, Gordon D; Lehnbom, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-15)
      Background: Documenting the indication on prescriptions and dispensed medicines labels is not standard practice in Australia. However, previous studies that have focused on the content and design of dispensed medicines labels, have suggested including the indication as a safety measure. The aim of this study was to investigate the perspectives of Australian consumers, pharmacists and prescribers ...

    • ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo 

      Samuelsen, Ørjan; Åstrand, Ove Alexander Høgmoen; Frøhlich, Christopher; Heikal, Adam; Skagseth, Susann; Carlsen, Trine Josefine Olsen; Leiros, Hanna-Kirsti S.; Bayer, Annette; Schnaars, Christian; Kildahl-andersen, Geir; Lauksund, Silje; Finke, Sarah; Huber, Sandra; Gjøen, Tor; Andresen, Adriana Magalhaes Santos; Økstad, Ole Andreas; Rongved, Pål (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-21)
      Carbapenem-resistant Gram-negative pathogens are a critical public health threat and there is an urgent need for new treatments. Carbapenemases (β-lactamases able to inactivate carbapenems) have been identified in both serine β-lactamase (SBL) and metallo-β-lactamase (MBL) families. The recent introduction of SBL carbapenemase inhibitors has provided alternative therapeutic options. Unfortunately, ...

    • α,α-disubstituted β-amino amides eliminate Staphylococcus aureus biofilms by membrane disruption and biomass removal 

      Ausbacher, Dominik; Miller, Lindsey A.; Goeres, Darla M.; Stewart, Philip S.; Strøm, Morten Bøhmer; Fallarero, Adyary (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-25)
      Bacterial biofilms account for up to 80% of all infections and complicate successful therapies due to their intrinsic tolerance to antibiotics. Biofilms also cause serious problems in the industrial sectors, for instance due to the deterioration of metals or microbial contamination of products. Efforts are put in finding novel strategies in both avoiding and fighting biofilms. Biofilm control is ...