• Mucoadhesive buccal films based on a graft co-polymer – A mucin-retentive hydrogel scaffold 

      Alopaeus, Julia Fredrika; Hellfritzsch, Marie; Gutowski, Tobias; Scherließ, Regina; Almeida, Andreia F; Sarmento, Bruno; Skalko-Basnet, Natasa; Tho, Ingunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-07)
      From a patient-centric perspective, oromucosal drug delivery is highly attractive due to the ease of administration without the need of swallowing, and improved patient safety. The aim of the presented work was to prepare a buccal film using a self-forming micellar drug solubiliser as the film matrix, combining it with a mucoadhesive polymer for an enhanced retention on the buccal mucosa. Specifically, ...