Blar i forfatter Artikler, rapporter og annet (farmasi) "Andreassen, Monica"

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    • Cry1Ab Protein from Bacillus thuringiensis and MON810 cry1Ab-transgenic Maize Exerts No Adjuvant Effect After Airway Exposure 

      Andreassen, Monica; Bøhn, Thomas; Wikmark, Odd Gunnar; van den Berg, Johnnie; Løvik, Martinus; Traavik, Terje; Nygaard, Unni Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-24)
      The genetically modified (GM) maize event MON810 has been inserted with a processed version of the transgene, cry1Ab, derived from the soil bacterium Bacillus thuringiensis (Bt) to express proteins with insecticidal properties. Such proteins may introduce new allergens and also act as adjuvants that promote allergic responses. While focus has been on safe consumption and hence the oral exposure to ...

    • Humoral and cellular immune responses in mice after airway administration of Bacillus thuringiensis Cry1Ab and MON810 cry1Ab-transgenic maize 

      Andreassen, Monica; Rocca, Elena; Bøhn, Thomas; Wikmark, Odd Gunnar; van den Berg, Johnnie; Løvik, Martinus; Traavik, Terje; Nygaard, Unni Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      Genetically modified (GM) crops may bring new proteins with immunogenic and allergenic properties into the food and feed chains. The most commonly grown GM maize, MON810, expresses a modified version of the insecticidal Cry1Ab protein originating in the soil bacterium Bacillus thuringiensis(Bt). Immune reactions following inhalation of pollen and debris from such plants have been scarcely studied. ...

    • Investigations of immunogenic, allergenic and adjuvant properties of Cry1Ab protein after intragastric exposure in a food allergy model in mice 

      Andreassen, Monica; Bøhn, Thomas; Wikmark, Odd Gunnar; Bodin, Johanna; Traavik, Terje; Løvik, Martinus; Nygaard, Unni Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-04)
      BACKGROUND In genetically modified (GM) crops there is a risk that the inserted genes may introduce new allergens and/or adjuvants into the food and feed chain. The MON810 maize, expressing the insecticidal Cry1Ab toxin, is grown in many countries worldwide. In animal models, intranasal and intraperitoneal immunisations with the purified Cry1Ab proteins have induced immune responses, and feeding ...