Blar i forfatter Artikler, rapporter og annet (kjemi) "Pandey, Sunil Kumar"

Viser treff 1-3 av 3

    • A Concise Total Synthesis of Breitfussin A and B 

      Pandey, Sunil Kumar; Guttormsen, Yngve; Haug, Bengt Erik; Hedberg, Christian; Bayer, Annette (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Total Synthesis of Phorbazole B 

      Guttormsen, Yngve; Fairhurst, Magnus John Espeland; Pandey, Sunil Kumar; Isaksson, Johan; Haug, Bengt Erik; Bayer, Annette (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-21)
      Phorbazoles are polychlorinated heterocyclic secondary metabolites isolated from a marine sponge and several of these natural products have shown inhibitory activity against cancer cells. In this work, a synthesis of the trichlorinated phorbazole B using late stage electrophilic chlorination was developed. The synthesis relied on the use of an oxazole precursor, which was protected with an iodine ...

    • Unequivocal structure confirmation of a breitfussin analog by anisotropic NMR measurements 

      Ndukwe, Ikenna E.; Lam, Yu-hong; Pandey, Sunil Kumar; Haug, Bengt Erik; Bayer, Annette; Sherer, Edward C.; Blinov, Kirill A.; Williamson, R. Thomas; Isaksson, Johan; Reibarkh, Mikhail; Liu, Yizhou; Martin, Gary E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-21)
      Structural features of proton-deficient heteroaromatic natural products, such as the breitfussins, can severely complicate their characterization by NMR spectroscopy. For the breitfussins in particular, the constitution of the five-membered oxazole central ring cannot be unequivocally established via conventional NMR methods when the 4′-position is halogenated. The level of difficulty is exacerbated ...