Berg, Kristel; Pedersen, Hege Lynum; Leiros, Ingar (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-09)
Iron is an essential nutrient for bacteria, however its propensity to form toxic hydroxyl radicals at high intracellular concentrations, requires its acquisition to be tightly regulated. Ferric uptake regulator (Fur) is a metal-dependent DNA-binding protein that acts as a transcriptional regulator in maintaining iron metabolism in bacteria and is a highly interesting target in the design of new ...