• Bioprospecting around Arctic islands: Marine bacteria as rich source of biocatalysts 

      De Santi, Concetta; Altermark, Bjørn; de Pascale, Donatella; Willassen, Nils Peder (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-11)
      We have investigated the biotechnological potential of Arctic marine bacteria for their ability to produce a broad spectrum of cold-active enzymes. Marine bacteria exhibiting these features are of great interest for both fundamental research and industrial applications. Macrobiota water and sediment samples have been collected during 2010 and 2011expeditions around the Lofoten and Svalbard islands. ...
    • Characterization of a cold-active and salt tolerant esterase identified by functional screening of Arctic metagenomic libraries 

      De Santi, Concetta; Altermark, Bjørn; Pierechod, Marcin Miroslaw; Ambrosino, Luca; de Pascale, Donatella; Willassen, Nils Peder (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-19)
      Background: The use of metagenomics in enzyme discovery constitutes a powerful approach to access to genomes of unculturable community of microorganisms and isolate novel valuable biocatalysts for use in a wide range of biotechnological and pharmaceutical fields. Results: Here we present a novel esterase gene (lip3) identified by functional screening of three fosmid metagenomic libraries, ...