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The Regulatory Relationship between E2F4 and MiRNA-363, and it’s Relevance to Oral Cancer
(Master thesis; Mastergradsoppgave, 2020-08-14)
BACKGROUND Oral Squamous Cell Carcinoma (OSCC) is the most common type of head and neck cancer and persists a leading cause of cancer associated mortality and morbidity universally. Survival rate is still poor at less than 50% urging the need for biomarkers to allow better diagnosis, prognosis and therapeutic strategies. In this study we focus on E2F4, a repressor of cell cycle, and further propose ...