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Binding mode of novel multimodal serotonin transporter compounds in 5-hydroxytryptamine receptors
(Master thesis; Mastergradsoppgave, 2016-06-01)
Antidepressants are the most common treatment of depression, one of the leading causes of suicide and disability worldwide. Currently marketed antidepressants have certain limitations; they have a delayed response time, only about 1/3 of the patients respond to the first agent prescribed, and many of them produce side effects that reduce the quality of life. The need for more efficacious and ...