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The expression of miR-21 in prostate cancer measured by in situ hybridization and its relevance as a diagnostic biomarker
(Master thesis; Mastergradsoppgave, 2012-12-15)
Background: Micro RNAs (miRNA) are a novel class of molecular regulators that have gained considerable attention in cancer research. Multiple studies in recent time have reported altered miRNA regulation in most cancers by deregulating of oncogenes and tumour suppressor genes. Additionally, certain tumours are represented by specific miRNA expression files. Prostate cancer is a markedly heterogeneous ...