Now showing items 1-2 of 2
Establishing a method for RNA immunoprecipitation to study interactions between long non-coding RNAs and proteins
(Master thesis; Mastergradsoppgave, 2012-12-17)
Long non-coding RNAs (lncRNAs) are involved in several important biological processes, and several lncRNAs have been associated with human diseases, particularly cancer. LncRNAs regulate gene expression at different levels. LncRNAs exert their functions through interactions with DNA, RNA or proteins. In this study, we established a method for investigating interactions between lncRNAs and protein ...
The expression of miR-21 in prostate cancer measured by in situ hybridization and its relevance as a diagnostic biomarker
(Master thesis; Mastergradsoppgave, 2012-12-15)
Background: Micro RNAs (miRNA) are a novel class of molecular regulators that have gained considerable attention in cancer research. Multiple studies in recent time have reported altered miRNA regulation in most cancers by deregulating of oncogenes and tumour suppressor genes. Additionally, certain tumours are represented by specific miRNA expression files. Prostate cancer is a markedly heterogeneous ...