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Now showing items 1-10 of 23
Application of Computational Drug Discovery Techniques for Designing New Drugs against Zika Virus
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-28)
Sámi reindeer governance in Norway as competing knowledge systems: a participatory study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017)
Using a participatory research approach, we assess the knowledge systems and political ontology of reindeer husbandry. The study was conducted by a mixed team of scientists and Sámi reindeer herders who practiced reindeer husbandry in West Finnmark, northern Norway, both prior to and during the state-led “rationalization” of Sámi reindeer husbandry since the late 1970s. The analysis is based on the ...
Direct-to-chip liquid cooling for reducing power consumption in a subarctic supercomputer centre
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016)
Reduction of data centre power consumption is a timely challenge. Waste heat reuse is another focus area when developing energy efficient and sustainable data centres. And these two issues are interconnected through liquid cooling of server racks and/or direct-to-chip liquid cooling. Both of these solutions make it possible to transfer a significant proportion of the waste heat energy back to ...
APECS : Nurturing a New Generation of Polar Researchers
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
Established in August 2006 by young researchers involved in the planning stages of the fourth International Polar Year (IPY 2007–2008), the Association of Polar Early Career Scientists (APECS) has evolved into the pre-eminent international organization for polar researchers at the beginning or early stages of their careers. Now comprising over 2,600 members from approximately 74 countries, APECS ...
Scientific (E)quality
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
The increased presence of women at all levels of higher education, from undergraduate student to full professor, has given increased currency to an argument that gender balance at the highest levels of academia will inevita- bly be achieved, merely through the passage of time. In this essay, that argument is challenged, both on the basis of its logic and on the basis of empirical studies on the rate ...
Sámi reindeer governance in Norway as competing knowledge-systems: A participatory study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017)
Using a participatory research approach, we assess the knowledge systems and political ontology of reindeer husbandry. The study was conducted by a mixed team of scientists and Sámi reindeer herders who practiced reindeer husbandry in West Finnmark, northern Norway, both prior to and during the state-led “rationalization” of Sámi reindeer husbandry since the late 1970s. The analysis is based on the ...
Simulating crude oil exposure, uptake and effects in North Atlantic Calanus finmarchicus populations
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-08)
A simulation model framework (SYMBIOSES) that includes a 3-dimensional ocean physics and biology model and a model for transport and fate of oil was used to investigate the potential for bioaccumulation and lethal/sublethal effects of oil components in the copepod <i>Calanus finmarchicus</i> in the Lofoten-Vesterålen archipelago of Norway. The oil model is coupled with the biology model by way of a ...
Synthesis and biological evaluations of marine oxohexadecenoic acids: PPARα/γ dual agonism and anti-diabetic target gene effects
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-18)
Obesity and associated disorders such as metabolic syndrome and type 2 diabetes (T2D) have reached epidemic proportions. Several natural products have been reported as Peroxisome Proliferator-Activated Receptor (PPAR) agonists, functioning as lead compounds towards developing new anti-diabetic drugs due to adverse side effects of existing PPAR drugs. We recently isolated and identified (7E)-9-oxoh ...
Molecular modelling, synthesis, and biological evaluations of a 3,5-disubstituted isoxazole fatty acid analogue as a PPARα-selective agonist
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-19)
The peroxisome proliferator activated receptors (PPARs) are important drug targets in treatment of metabolic and inflammatory disorders. Fibrates, acting as PPARα agonists, have been widely used lipid-lowering agents for decades. However, the currently available PPARα targeting agents show low subtype-specificity and consequently a search for more potent agonists have emerged. In this study, previously ...
Gender equality for a thriving, sustainable arctic
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-29)
On 21 May 2021, a milestone Pan-Arctic Report: Gender Equality in the Arctic was published in tandem with the Arctic Council’s Ministerial Meeting held in Reykjavík, 19–20 May 2021. This article provides a brief review of the report and its major findings across six chapters that address key themes concerning gender equality in the Arctic: Law and Governance, Security, Gender and Environment, Migration ...