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Molecular targets and biological effects of PAX6 in lung cancer
(Master thesis; Mastergradsoppgave, 2013-05-15)
Lung cancer is by far the leading cause of cancer-related mortality worldwide regardless of sex, and has a dismal overall 5-year survival rate of approximately 15%. More than 85% of all lung cancers are non-small cell lung cancer (NSCLC), and about 50% of these are adenocarcinomas. Targeted treatment has shown promising results in treating certain types of NSCLC, but the overall survival is still ...