Viser treff 1384-1403 av 10096

    • Chitosan-coated liposomes for topical vaginal therapy: Assuring localized drug effect 

      Jøraholmen, May Wenche; Vanić, Željka; Tho, Ingunn; Škalko-Basnet, Nataša (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      The choice of drug therapy in pregnant patients suffering from vaginal infections is limited by the safety profile of the drug. Assuring the efficient topical therapy to avoid systemic absorption is considered the best therapy option. Chitosan-coated liposomes have been developed and optimized to assure localized therapy of clotrimazole. Chitosan was selected as mucoadhesive polymer both to prolong ...
    • Chitosomes-In-Chitosan Hydrogel for Acute Skin Injuries: Prevention and Infection Control 

      Hemmingsen, Lisa Myrseth; Julin, Kjersti; Ahsan, Luqman; Basnet, Purusotam; Johannessen, Mona; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-12)
      Burns and other skin injuries are growing concerns as well as challenges in an era of antimicrobial resistance. Novel treatment options to improve the prevention and eradication of infectious skin biofilm-producing pathogens, while enhancing wound healing, are urgently needed for the timely treatment of infection-prone injuries. Treatment of acute skin injuries requires tailoring of formulation to ...
    • Chlamydia pecorum associated with an outbreak of infectious keratoconjunctivitis in semi-domesticated reindeer in Sweden 

      Sanchez Romano, Javier; Leijon, Mikael; Hagström, Åsa; Jinnerot, Tomas; Rockström, Urlika; Tryland, Morten (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-05)
      Infectious keratoconjunctivitis (IKC), the most common ocular disease in ruminants worldwide, has affected semi-domesticated Eurasian reindeer (<i>Rangifer tarandus tarandus</i>) for over 100 years, both as individual cases and in outbreaks affecting tens to hundreds of animals. Recurrent IKC outbreaks have been affecting a semi-domesticated reindeer herd in Östra Kikkejaure (Norrbotten county, ...
    • Chlorhexidine compounds in cosmetic products Risk assessment of antimicrobial and antibiotic resistance development in microorganisms 

      Lunestad, Bjørn Tore; Møretrø, Trond; Hegstad, Kristin; Langsrud, Solveig; Scheie, Anne Aamdal; Kapperud, Georg; Lassen, Jørgen Fr; Nygård, Karin Maria; Robertson, Lucy; Nesbakken, Truls; Olsvik, Ørjan; Tranulis, Michael A.; Tryland, Morten; Rimstad, Espen (Research report; Forskningsrapport, 2010-04-15)
      Chlorhexidine and its salts are reported as being used in cosmetics as an active ingredient to give the desired effect or as a preservative in concentrations of up to 0.3 %. Such products include mouthwashes, hair dying and bleaching formulations, shampoos, anti hair “aging” products and exfoliants, body lotions, eye creams, face cleansers, sun cream, after-sun lotions, ...
    • Choice is not the issue. The misrepresentation of healthcare in bioethical discourse 

      Agledahl, Kari Milch; Førde, Reidun; Wifstad, Åge (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-03-17)
      The principle of respect for autonomy has shaped much of the bioethics' discourse over the last 50 years, and is now most commonly used in the meaning of respecting autonomous choice. This is probably related to the influential concept of informed consent, which originated in research ethics and was soon also applied to the field of clinical medicine. But while available choices in medical research ...
    • Choice of immunoassay to evaluate porcine cytokine levels 

      Ueland, Nora Lamark; Ludvigsen, Judith K.; Hellerud, Bernt C; Mollnes, Tom Eirik; Skjeflo, Espen Waage (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-06)
      <i>Background</i> - In order to adequately monitor cytokines in experimental models, currently available methods and commercially available kits should be compared.<br><br> <i>Aim</i> - To compare the plasma and tissue concentrations of IL-1β, IL-6, IL-8, IL-10, and TNF as a measure of systemic inflammation in septic pigs.<br><br> <i>Methods</i> - Cytokines were quantified from blood and tissue ...
    • Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF 

      Nymo, Stig Haugset; Niyonzima, Nathalie; Espevik, Terje; Mollnes, Tom Eirik (Journal article; Tidsskriftartikkel, 2014-07-05)
      Cholesterol crystals are known to be a hallmark of atherosclerosis with recent studies demonstrating deposition of these crystals in early fatty streak formation as well as penetrating the intima following plaque rupture. Inflammation has also become a central focus in atheroma development and endothelial cell activation is recognized as necessary for the recruitment of inflammatory cells to the ...
    • "Choosing to live". Experiences of coping in recovery from drug addiction - a phenomenological study 

      Blindheim, Line Grebstad (Master thesis; Mastergradsoppgave, 2016-05-02)
      Abstract Substance addiction is detrimental to the addict, their family, social environment and society as a whole, which is why research needs to approach it with problem solving in mind. The present study has a salutogenic health perspective, and focuses on coping in recovery from substance addiction. The informants’ experiences of coping were explored using the qualitative approach. The informants ...
    • Chromosomal microarray in prenatal diagnosis - replacing traditional karyotyping 

      Winther, Alise Marie (Master thesis; Mastergradsoppgave, 2019-06-02)
      Abstract Background: In prenatal diagnosis, chromosomal microarray analysis (CMA) has not yet fully replaced conventional karyotyping. As CMA is able to detect smaller genomic imbalances compared to conventional karyotyping, it has become the first-tier test in pregnancies with ultrasound abnormalities. Objectives/aims: The aim of the study was to learn about CMA and its appliance in invasive ...
    • The Chronic Care Model and technological research and innovation: A scoping review at the crossroad 

      Gammon, Barbara Deede; Berntsen, Gro Karine Rosvold; Koricho, Absera Teshome; Sygna, Karin; Ruland, Cornelia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-06)
      Background: Information and communication technologies (ICT) are key to optimizing the outcomes of the Chronic Care Model (CCM), currently acknowledged as the best synthesis of available evidence for chronic illness prevention and management. At the same time, CCM can offer a needed framework for increasing the relevance and feasibility of ICT innovation and research in health care. Little is known ...
    • Chronic hepatitis C: Epidemiology, viral resistance, and public health implications 

      Kileng, Hege (Doctoral thesis; Doktorgradsavhandling, 2019-06-14)
      Chronic hepatitis C: Epidemiology, viral resistance, and public health implications Chronic hepatitis C virus (HCV) infection can progress to cirrhosis and end-stage liver disease. The infection is frequently asymptomatic, leaving many infected individuals unaware of the diagnosis until complications occur. The total number of HCV infections is projected to remain stable or to decline, but the ...
    • Chronic iron deficiency and anaemia were highly prevalent in a population-based longitudinal study among adolescent girls 

      Stabell, Niklas; Averina, Maria; Flægstad, Trond (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-01)
      <b>Aim:</b> The combination of iron deficiency and anaemia is a major health problem, and adolescents are an at- risk group. The main aim of this study was to explore the mag-nitude of these conditions among adolescents aged 15–19 and identify possible as-sociated risk factors. <br><b>Methods:</b> This population- based longitudinal study of adolescents in North Norway was conducted in 2010–2011, ...
    • Chronic kidney disease in patients with diabetes mellitus 

      Nordheim, Espen; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-29)
      Chronic kidney disease is a common complication and concomitant condition of diabetes mellitus. The treatment of patients with diabetes and chronic kidney disease, including intensive control of blood sugar and blood pressure, has been very similar for type 1 and type 2 diabetes patients. New therapeutic targets have shown promising results and may lead to more specific treatment options for patients ...
    • Chronic nasal carriage of Staphylococcus aureus in granulomatosis with polyangiitis patients receiving rituximab maintenance: friend or foe? 

      Besada, Emilio; Koldingsnes, Wenche; Nossent, Johannes C (Journal article; Tidsskriftartikkel, 2014)
    • Chronic nonbacterial osteomyelitis — clinical and magnetic resonance imaging features 

      d’Angelo, Paola; de Horatio, Laura Tanturri; Toma, Paolo; Ording Müller, Lil-Sofie; Avenarius, Derk; von Brandis, Elisabeth; Zadig, Pia; Casazza, Ines; Pardeo, Manuela; Pires-Marafon, Denise; Capponi, Martina; Insalaco, Antonella; Fabrizio, Benedetti; Rosendahl, Karen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-09)
      <i>Background</i> - Chronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory bone disorder. Little information exists on the use of imaging techniques in CNO.<p> <p><i>Materials and methods</i> - We retrospectively reviewed clinical and MRI findings in children diagnosed with CNO between 2012 and 2018. Criteria for CNO included unifocal or multifocal inflammatory bone lesions, symptom ...
    • Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. 

      Cook, Sarah; Eggen, Anne Elise; Hopstock, Laila Arnesdatter; Malyutina, S; Shapkina, M; Kudryavtsev, Alexander V; Melbye, Hasse; Quint, JK (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-14)
      Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Despite a high prevalence of smoking and respiratory symptoms, two recent population-based studies in Russia found a relatively low prevalence of obstructive lung function. Here, we investigated the prevalence of both obstructive lung disease and respiratory symptoms in a population-based ...
    • Chronic obstructive pulmonary Disease and risk of mortality in patients with venous thromboembolism - the Tromsø Study 

      Børvik, Trond; Brækkan, Sigrid Kufaas; Evensen, Line; Brodin, Ellen Elisabeth; Morelli, Vania Maris; Melbye, Hasse; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-30)
      <i>Background</i> - Previous studies have shown increased mortality in venous thromboembolism (VTE) patients with chronic obstructive pulmonary disease (COPD), but it is unknown to what extent the association is influenced by the severity of COPD and physical inactivity.<p> <p><i>Objectives</i> - This article investigates whether COPD, and stages of COPD, influenced the risk of mortality after a ...
    • Chronic obstructive pulmonary disease does not impair responses to resistance training 

      Mølmen, Knut Sindre; Hammarström, Jens Konrad Daniel; Falch, Gunnar Slettaløkken; Grundtvig, Morten; Koll, Lise; Hanestadhaugen, Marita; Khan, Yusuf; Ahmad, Rafi; Malerbakken, Bente; Rødølen, Tore Jørgen; Lien, Roger; Rønnestad, Bent; Raastad, Truls; Ellefsen, Stian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-06)
      <i>Background</i> - Subjects with chronic obstructive pulmonary disease (COPD) are prone to accelerated decay of muscle strength and mass with advancing age. This is believed to be driven by disease-inherent systemic pathophysiologies, which are also assumed to drive muscle cells into a state of anabolic resistance, leading to impaired abilities to adapt to resistance exercise training. Currently, ...
    • Chronic pain concepts of pediatricians: a qualitative survey 

      Locher, Cosima; Wörner, Andreas; Carlander, Maria; Kossowsky, Joe; Dratva, Julia; Koechlin, Helen (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01)
      Introduction: Chronic pain is a prevalent, yet underrecognized, condition in children and adolescents. A biopsychosocial framework has been widely adopted over the past decades and resulted in a new pain classification in the International Classification of Diseases, 11th revision (ICD-11). Nevertheless, little is known about pediatricians' pain concepts.<p> <p>Objectives: We explored pain ...