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Viser treff 2102-2121 av 10096

    • Determinants of Staphylococcus aureus colonization and infection: Characterization of interaction between serine-aspartate containing protein D and human Siglec11 and Siglec16 

      Spahiu, Ira (Master thesis; Mastergradsoppgave, 2021-10-15)
      <p><i>Staphylococcus aureus</i> is a Gram-positive opportunistic pathogen responsible for a range of infections that can lead to fatal invasive diseases such as pneumonia or osteomyelitis. Approximately 30% of the healthy adult population are persistently colonized by <i>S. aureus</i> strains in their anterior nares. The molecular mechanism underlying <i>S. aureus</i> colonization and infection ...

    • Determinants of trabecular bone score and prevalent vertebral fractures in women with fragility fractures: a cross-sectional sub-study of NoFRACT 

      Borgen, Tove Tveitan; Bjørnerem, Åshild; Solberg, Lene Bergendal; Andreasen, Camilla; Brunborg, C.; Stenbro, May-Britt; Hübschle, Lars Michael; Figved, Wender; Apalset, Ellen Margrete; Gjertsen, Jan Erik; Basso, Trude; Lund, Ida; Hansen, Ann Kristin; Stutzer, Jens-Meinhard; Dahl, Cecilie; Nordsletten, Lars; Frihagen, Frede; Eriksen, Erik Fink (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-21)
      <i>Summary</i> - Determinants of trabecular bone score (TBS) and vertebral fractures assessed semiquantitatively (SQ1–SQ3) were studied in 496 women with fragility fractures. TBS was associated with age, parental hip fracture, alcohol intake and BMD, not SQ1–SQ3 fractures. SQ1–SQ3 fractures were associated with age, prior fractures, and lumbar spine BMD, but not TBS.<p><p> <i>Introduction</i> ...

    • Determination of copy number and circularization ratio of Tn916-Tn1545 family of conjugative transposons in oral streptococci by droplet digital PCR 

      Lunde, Tracy Munthali; Al-Haroni, Mohammed; Roberts, Adam P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-06)
      <p><I>Background</I>: Tn916 and Tn1545 are paradigms of a large family of related, broad host range, conjugative transposons that are widely distributed in bacteria and contribute to the spread of antibiotic resistance genes (ARGs). Variation in the copy number (CN) of Tn916-Tn1545 elements and the circularization ratio (CR) may play an important role in propagation of ARGs carried by these ...

    • Determination of Cysteine Connectivity in Bioactive Peptides 

      Moen, Merete Kveli (Master thesis; Mastergradsoppgave, 2014-05-20)
      Conotoxins are diverse and well-studied, and is therefore suited as a model to develop a general method for analyzing disulfide-rich peptides. To investigate the folding of both commercially available and self-synthesized Conotoxins, an UHPLC-MS/MS method was developed where one disulfide-bridge was reduced at the time and alkylated with different maleimides. The results from the UHPLC-MS/MS method ...

    • Determination of the binding mode for the cyclopentapeptide CXCR4 antagonist FC131 using a dual approach of ligand modifications and receptor mutagenesis 

      Thiele, Stefanie; Mungalpara, Jignesh; Steen, A.; Rosenkilde, Mette M.; Våbenø, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Determining the safety and effectiveness of Tai Chi: a critical overview of 210 systematic reviews of controlled clinical trials 

      Yang, Guo-Yan; Hunter, Jennifer; Bu, Fan-Long; Hao, Wen-Li; Zhang, Han; Wayne, Peter M.; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-03)
      Background - This overview summarizes the best available systematic review (SR) evidence on the health effects of Tai Chi.<p> <p>Methods - Nine databases (PubMed, Cochrane Library, EMBASE, Medline, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP), Sino-Med, and Wanfang Database) were searched for SRs of controlled clinical trials of Tai Chi ...

    • Developement of mucoadhesive polymer-coated liposomes for hydration of the oral mucosa 

      Saleh, Rebwar Salar Nori (Master thesis; Mastergradsoppgave, 2013-05-18)
      Dry mucus in the oral cavity is uncomfortable for patients and can lead to other additional illnesses. Reduced or absence of saliva secretion, caused by the diseases, side effects of drugs, aging, or radiotherapy, can result in issues related to xerostomia and dental health. A system that could contribute to increased hydration of the mucus would reduce the discomfort for the patient. In addition, ...

    • Developing a Linear Mixed Model to Predict RPE and sRPE in Female Elite Football Players Using External Load Measures 

      Vollstad, Jakob Kjos (Master thesis; Mastergradsoppgave, 2023-05-15)
      Abstract Introduction: Despite the broad consensus on the importance of training load monitoring and management for footballers’ performance, existing research on female football players remains scarce. The present study aimed to develop and evaluate a linear mixed model (LMM) to predict the rating of perceived exertion (RPE) and session RPE (sRPE) in female elite football players using GPS-derived ...

    • Developing a machine learning model for tumor cell quantification in standard histology images of lung cancer 

      Kristoffersen, Siri (Master thesis; Mastergradsoppgave, 2023-05-31)
      Summary Background Tumor purity estimation plays a crucial role in genomic profiling and is traditionally carried out manually by pathologists. This manual approach has several disadvantages, including potential inaccuracies due to human error, inconsistency in evaluation criteria among different pathologists, and the time-consuming nature of the process. These issues may be addressed by adopting ...

    • Developing a model for measuring fear of pain in Norwegian samples: The Fear of Pain Questionnaire Norway 

      Vambheim, Sara Magelssen; Lyby, Peter Solvoll; Aslaksen, Per M; Flaten, Magne; Åsli, Ole; Bjørkedal, Espen; Martinussen, Laila Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-01)
      <p><i>Background - </i>Fear of pain is highly correlated with pain report and physiological measures of arousal when pain is inflicted. The Fear of Pain Questionnaire III (FPQ-III) and The Fear of Pain Questionnaire Short Form (FPQ-SF) are self-report inventories developed for assessment of fear of pain (FOP). A previous study assessed the fit of the FPQ-III and the FPQ-SF in a Norwegian non-clinical ...

    • Developing Large-scale Electronic Patient Records Conforming to the openEHR Architecture 

      Ellingsen, Gunnar; Christensen, Bente; Silsand, Line (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Developing professional competence by internetbased reflection 

      Aars, Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2008)
      This article aims at giving an example of how practical, clinical knowledge can be explored by the use of a tailor-made Information and Communication Technology (ICT)-tool: Physio-Net. In constructing content to this particular internet- based resource used for bachelor students at Tromsø University College, a clinician expert physiotherapist contributed with a detailed analysis of her own ...

    • Developing professional competence in an unfamiliar setting: Practice learning in Zambia 

      Olsen, Marianne; Jentoft, Rita (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-29)
      Background: Higher education needs to provide students with competencies to meet the health and social needs of a society characterised by increased globalisation and diversity. Occupational therapy students from Norway expressed that learning experiences outside their comfort zone within Zambian placements, have had a profound impact on their professional competence.<p> <p>Aims and objectives: ...

    • The Development and Acceptability of a Wilderness Programme to Support the Health and Well-Being of Adolescent and Young Adult Cancer Survivors: The WAYA Programme 

      Jong, Miek; Stub, Trine; Mulder, Eric; Jong, Mats (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-22)
      Detailed descriptions of theory, structure, and activities with causal links to specified outcomes of wilderness programs are lacking. Addressing this gap, the present qualitative study gives a thorough description of the development of the Wilderness programme for Adolescent and Young Adult (AYA) cancer survivors (WAYA). WAYA is adapted to the individual needs of AYA cancer survivors. It was ...

    • Development and evaluation of a test program for Y-site compatibility testing of total parenteral nutrition and intravenous drugs 

      Staven, Vigdis; Wang, Siri; Grønlie, Ingrid; Tho, Ingunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-22)
      Background: There is no standardized procedure or consensus to which tests should be performed to judge compatibility/ incompatibility of intravenous drugs. The purpose of this study was to establish and evaluate a test program of methods suitable for detection of physical incompatibility in Y-site administration of total parenteral nutrition (TPN) and drugs. Methods: Eight frequently used methods ...

    • Development and evaluation of gonadotropin releasing hormone antagonists as SPECT radiotracers 

      Fjellaksel, Richard (Doctoral thesis; Doktorgradsavhandling, 2018-05-24)
      The overall aim of the thesis was to evaluate the potential of gonadotropin releasing hormone receptor (GnRH-R) antagonists as radiotracers for the early detection and understanding of Alzheimer`s disease (AD). The molecular imaging field is a symbiosis between organic chemistry, radiochemistry, in vitro biology, as well as preclinical- and clinical trials, therefore an evaluation should involve all ...

    • Development and optimization of a new processing approach for manufacturing topical liposomes-in-hydrogel drug formulations by dual asymmetric centrifugation 

      Ingebrigtsen, Sveinung Gaarden; Skalko-Basnet, Natasa; Holsæter, Ann Mari (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-24)
      Objectives: The objective of the present study was to utilize dual asymmetric centrifugation (DAC) as a novel processing approach for the production of liposomes-in-hydrogel formulations. <br>Materials and Methods: Lipid films of phosphatidylcholine, with and without chloramphenicol (CAM), were hydrated and homogenized by DAC to produce liposomes in the form of vesicular phospholipid gels with a ...

    • Development and Psychometric Testing of the Student Learning in Emergencies Checklist (SLEC): Measuring Promotors of Academic Functioning and Wellbeing in Palestinian Youth Affected by War and Conflict 

      Forsberg, June Thorvaldsen; Dolan, Carly Tubbs; Schultz, Jon Håkon (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-27)
      Youth living with war and ongoing conflict are frequently exposed to potentially traumatic events and cumulative stress which can result in temporarily impaired academic functioning and reduced wellbeing in school. In Palestine, the Ministry of Education has included psychosocial support programmes in the schools for the purpose of reducing stress reactions and improving school functioning ...

    • The development and use of a new tool for estimating individual sun induced vitamin D in epidemiological surveys 

      Edvardsen, Kåre (Doctoral thesis; Doktorgradsavhandling, 2010-11-19)

    • Development and Validation of a Deep Learning Method to Predict Cerebral Palsy From Spontaneous Movements in Infants at High Risk 

      Groos, Daniel; Adde, Lars; Aubert, Sindre Aarnes; Boswell, Lynn; De Regnier, Raye-Ann; Fjørtoft, Toril Larsson; Gaebler-Spira, Deborah; Haukeland, Andreas; Loennecken, Marianne; Msall, Michael; Moinichen, Unn Inger; Pascal, Aurelie; Peyton, Colleen; Ramampiaro, Heri; Schreiber, Michael D.; Silberg, Inger Elisabeth; Songstad, Nils Thomas; Thomas, Niranjan; van den Broeck, Christine; Øberg, Gunn Kristin; Ihlen, Espen Alexander F.; Støen, Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-11)
      Importance Early identification of cerebral palsy (CP) is important for early intervention, yet expert-based assessments do not permit widespread use, and conventional machine learning alternatives lack validity. Objective To develop and assess the external validity of a novel deep learning–based method to predict CP based on videos of infants’ spontaneous movements at 9 to 18 weeks’ corrected ...