Viser treff 2113-2132 av 10096

    • Developing professional competence by internetbased reflection 

      Aars, Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2008)
      This article aims at giving an example of how practical, clinical knowledge can be explored by the use of a tailor-made Information and Communication Technology (ICT)-tool: Physio-Net. In constructing content to this particular internet- based resource used for bachelor students at Tromsø University College, a clinician expert physiotherapist contributed with a detailed analysis of her own ...
    • Developing professional competence in an unfamiliar setting: Practice learning in Zambia 

      Olsen, Marianne; Jentoft, Rita (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-29)
      Background: Higher education needs to provide students with competencies to meet the health and social needs of a society characterised by increased globalisation and diversity. Occupational therapy students from Norway expressed that learning experiences outside their comfort zone within Zambian placements, have had a profound impact on their professional competence.<p> <p>Aims and objectives: ...
    • The Development and Acceptability of a Wilderness Programme to Support the Health and Well-Being of Adolescent and Young Adult Cancer Survivors: The WAYA Programme 

      Jong, Miek; Stub, Trine; Mulder, Eric; Jong, Mats (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-22)
      Detailed descriptions of theory, structure, and activities with causal links to specified outcomes of wilderness programs are lacking. Addressing this gap, the present qualitative study gives a thorough description of the development of the Wilderness programme for Adolescent and Young Adult (AYA) cancer survivors (WAYA). WAYA is adapted to the individual needs of AYA cancer survivors. It was ...
    • Development and evaluation of a test program for Y-site compatibility testing of total parenteral nutrition and intravenous drugs 

      Staven, Vigdis; Wang, Siri; Grønlie, Ingrid; Tho, Ingunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-22)
      Background: There is no standardized procedure or consensus to which tests should be performed to judge compatibility/ incompatibility of intravenous drugs. The purpose of this study was to establish and evaluate a test program of methods suitable for detection of physical incompatibility in Y-site administration of total parenteral nutrition (TPN) and drugs. Methods: Eight frequently used methods ...
    • Development and evaluation of gonadotropin releasing hormone antagonists as SPECT radiotracers 

      Fjellaksel, Richard (Doctoral thesis; Doktorgradsavhandling, 2018-05-24)
      The overall aim of the thesis was to evaluate the potential of gonadotropin releasing hormone receptor (GnRH-R) antagonists as radiotracers for the early detection and understanding of Alzheimer`s disease (AD). The molecular imaging field is a symbiosis between organic chemistry, radiochemistry, in vitro biology, as well as preclinical- and clinical trials, therefore an evaluation should involve all ...
    • Development and optimization of a new processing approach for manufacturing topical liposomes-in-hydrogel drug formulations by dual asymmetric centrifugation 

      Ingebrigtsen, Sveinung Gaarden; Skalko-Basnet, Natasa; Holsæter, Ann Mari (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-24)
      Objectives: The objective of the present study was to utilize dual asymmetric centrifugation (DAC) as a novel processing approach for the production of liposomes-in-hydrogel formulations. <br>Materials and Methods: Lipid films of phosphatidylcholine, with and without chloramphenicol (CAM), were hydrated and homogenized by DAC to produce liposomes in the form of vesicular phospholipid gels with a ...
    • Development and Psychometric Testing of the Student Learning in Emergencies Checklist (SLEC): Measuring Promotors of Academic Functioning and Wellbeing in Palestinian Youth Affected by War and Conflict 

      Forsberg, June Thorvaldsen; Dolan, Carly Tubbs; Schultz, Jon Håkon (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-27)
      Youth living with war and ongoing conflict are frequently exposed to potentially traumatic events and cumulative stress which can result in temporarily impaired academic functioning and reduced wellbeing in school. In Palestine, the Ministry of Education has included psychosocial support programmes in the schools for the purpose of reducing stress reactions and improving school functioning ...
    • The development and use of a new tool for estimating individual sun induced vitamin D in epidemiological surveys 

      Edvardsen, Kåre (Doctoral thesis; Doktorgradsavhandling, 2010-11-19)
    • Development and Validation of a Deep Learning Method to Predict Cerebral Palsy From Spontaneous Movements in Infants at High Risk 

      Groos, Daniel; Adde, Lars; Aubert, Sindre Aarnes; Boswell, Lynn; De Regnier, Raye-Ann; Fjørtoft, Toril Larsson; Gaebler-Spira, Deborah; Haukeland, Andreas; Loennecken, Marianne; Msall, Michael; Moinichen, Unn Inger; Pascal, Aurelie; Peyton, Colleen; Ramampiaro, Heri; Schreiber, Michael D.; Silberg, Inger Elisabeth; Songstad, Nils Thomas; Thomas, Niranjan; van den Broeck, Christine; Øberg, Gunn Kristin; Ihlen, Espen Alexander F.; Støen, Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-11)
      Importance Early identification of cerebral palsy (CP) is important for early intervention, yet expert-based assessments do not permit widespread use, and conventional machine learning alternatives lack validity. Objective To develop and assess the external validity of a novel deep learning–based method to predict CP based on videos of infants’ spontaneous movements at 9 to 18 weeks’ corrected ...
    • Development and validation of a lifestyle-based model for colorectal cancer risk prediction: the LiFeCRC score 

      Aleksandrova, Krasimira; Reichmann, Robin; Kaaks, Rudolf; Jenab, Mazda; Bueno-de-Mesquita, Hendrik Bastiaan; Dahm, Christina C.; Eriksen, Anne Kirstine; Tjønneland, Anne; Artaud, Fanny; Boutron-Ruault, Marie-Christine; Hüsing, Anika; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Panico, Salvatore; Grioni, Sara; Sacerdote, Carlotta; Tumino, Rosario; Elias, Sjoerd G.; May, Anne M.; Sandanger, Torkjel M; Skeie, Guri; Sánchez, Maria-Jose; Huerta, José María; Sala, Núria; Gurrea, Aurelio Barricarte; Amiano, Pilar; Drake, Isabel; van Guelpen, Bethany; Key, Tim; Weiderpass, Elisabete; Aglago, Elom K.; Cross, Amanda J.; Tsilidis, Konstantinos K.; Riboli, Elio; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-04)
      <b>Background</b> Nutrition and lifestyle have been long established as risk factors for colorectal cancer (CRC). Modifiable lifestyle behaviours bear potential to minimize long-term CRC risk; however, translation of lifestyle information into individualized CRC risk assessment has not been implemented. Lifestyle-based risk models may aid the identification of high-risk individuals, guide referral ...
    • Development and validation of a simple online-SPE method coupled to high-resolution mass spectrometry for the analysis of stanozolol-N-glucuronides in urine samples 

      Göschl, Lorenz; Gmeiner, Günter; Enev, Valentin S; Kratena, Nicolas; Gärtner, Peter; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-17)
      Stanozolol is still the most commonly used illicit anabolic‐androgenic steroid (AAS) in professional sports. Therefore, accurate and fast analysis and long detection windows are of great interest in the field of antidoping analysis. In this work, a very simple, fast, and highly sensitive online solid‐phase extraction method coupled with liquid chromatography–high‐resolution tandem mass spectrometry ...
    • Development and validation of an instrument to assess oral health literacy in Norwegian adult dental patients 

      Stein, Linda Maria; Pettersen, Kjell Sverre; Bergdahl, Maud; Bergdahl, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-05)
      Objective: To develop and validate an interview instrument to assess oral health literacy in Norwegian adult dental patients. <p/>Materials and methods: The instrument, Adult Health Literacy Instrument for Dentistry (AHLID), was based on an OECD instrument used to assess general literacy in adults. 130 Norwegian adults (mean age 48 years; 57% women) participated. AHLID included a selection of ...
    • Development and validation of circulating CA125 prediction models in postmenopausal women 

      Sasamoto, Naoko; Babic, Ana; Rosner, Bernard A.; Fortner, Renée T.; Vitonis, Allison F; Yamamoto, Hidemi; Fichorova, Raina N.; Titus, Linda J.; Tjønneland, Anne; Hansen, Louise; Kvaskoff, Marina; Fournier, Agnès; Mancini, Francesca Romana; Boeing, Heiner; Trichopoulou, Antonia; Peppa, Eleni; Karakatsani, Anna; Palli, Domenico; Grioni, Sara; Mattiello, Amalia; Tumino, Rosario; Fiano, Valentina; Onland-Moret, N. Charlotte; Weiderpass, Elisabete; Gram, Inger Torhild; Quirós, José Ramón; Lujan-Barroso, Leila; Sánchez, María-José; Colorado-Yohar, Sandra; Barricarte, Aurelio; Amiano, Pilar; Idahl, Annika; Lundin, Eva; Sartor, Hanna; Khaw, Kay-Tee; Key, Timothy J.; Muller, David; Riboli, Elio; Gunter, Marc; Dossus, Laure; Trabert, Britton; Wentzensen, Nicolas; Kaaks, Rudolf; Cramer, Daniel W.; Tworoger, Shelley S.; Terry, Kathryn L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-26)
      <i>Background</i> - Cancer Antigen 125 (CA125) is currently the best available ovarian cancer screening biomarker. However, CA125 has been limited by low sensitivity and specificity in part due to normal variation between individuals. Personal characteristics that influence CA125 could be used to improve its performance as screening biomarker.<p><p> <i>Methods</i> - We developed and validated ...
    • Development and validation of the Efficacy Safety Score (ESS), a novel tool for postoperative patient management 

      Skraastad, Erlend Johan; Ræder, Johan; Dahl, Vegard; Bjertnæs, Lars J.; Kuklin, Vladimir (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-28)
      Background: <br> Several reports have shown that postoperative monitoring of general safety and quality issues, including pain treatment, after discharge from recovery is often non-systematic and inadequate. We suggest a new score with assessment of key recovery parameters, as a supportive tool for postoperative care and a call-out algorithm for need of extra help. The aim of this investigation ...
    • The development journey of an artificial intestinal model predicting oral drug absorption: the mucus-PVPA model 

      Falavigna, Margherita (Doctoral thesis; Doktorgradsavhandling, 2021-04-23)
      Oral drug administration is the most convenient route to systemically deliver drugs because of its cost-effectiveness, ease of administration and high patient compliance. However, when a drug is orally administered it will be exposed to the different physiological processes and environments found along the gastrointestinal (GI) tract, which will determine its ability of being absorbed and reach the ...
    • Development of 8f-labeled radiotracers for pet imaging of the adenosine a2a receptor: Synthesis, radiolabeling and preliminary biological evaluation 

      Lai, Thu Hang; Schröder, Susann; Toussaint, Magali; Dukić-Stefanović, Sladjana; Kranz, Mathias; Ludwig, Friedrich-Alexander; Fischer, Steffen; Steinbach, Jörg; Deuther-Conrad, Winnie; Brust, Peter; Moldovan, Rareş-Petru (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-25)
      The adenosine A<sub>2A</sub> receptor (A<sub>2A</sub>R) represents a potential therapeutic target for neurodegenerative diseases. Aiming at the development of a positron emission tomography (PET) radiotracer to monitor changes of receptor density and/or occupancy during the A<sub>2A</sub>R-tailored therapy, we designed a library of fluorinated analogs based on a recently published lead compound ...
    • Development of a biomimetic phospholipid vesicle-based permeation assay for the estimation of intestinal drug permeability 

      Naderkhani, Elenaz; Isaksson, Johan; Ryzhakov, Alexey; Flaten, Gøril Eide (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Development of a Clinical Scandinavian Registry for Hidradenitis Suppurativa; HISREG 

      Ingvarsson, Gisli; Dufour, Deirdre Nathalie; Killasli, Hassan; Sartorius, Karin; Lapins, Jan; Skau, Philip; Moseng, Dagfinn; Dinparvar, Darjosh; Furberg, Anne-Sofie; Jemec, Gregor B.E.; Emtestam, Lennart (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Hidradenitis suppurativa (HS; or acne inversa) is a scarring and frequently persistent inflammatory disorder of the terminal hair follicles of apocrine gland-bearing skin in adults. Treatments include local or systemic antibiotics, hormones, retinoids and systemic immunosuppressive agents (1), although on evaluation these have been shown to have only limited or temporary effect. In refractory cases, ...
    • Development of a feasible and responsive ultrasound inflammation score for rheumatoid arthritis through a data-driven approach 

      Aga, Anna-Birgitte; Hammer, Hilde Berner; Olsen, Inge Christoffer; Uhlig, Till; Kvien, Tore Kristian; Heijde, Desirée van der; Fremstad, Hallvard; Madland, Tor Magne; Lexberg, Åse; Haukeland, Hilde; Rødevand, Erik; Høili, Christian; Stray, Hilde; Noraas, Anne Lindtner; Hansen, Inger Johanne Widding; Bakland, Gunnstein; Lillegraven, Siri; Lie, Elisabeth; Haavardsholm, Espen A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-16)
      Objective: To develop and validate a responsive and feasible ultrasound inflammation score for rheumatoid arthritis (RA). Methods: We used data from cohorts of early RA (development) and established RA starting/switching biologic therapy (validation). 4 tendons and 36 joints were examined by a grey scale (GSUS) and power Doppler semiquantitative ultrasound (PDUS) scoring system (full score). ...
    • Development of a homologous gene replacement approach to study ciprofloxacin resistance in clinical Escherichia coli isolates 

      Valla, Sanne Ekroll (Master thesis; Mastergradsoppgave, 2017-05-15)
      Urinary tract infections are common amongst infectious diseases in humans, and often these infections are caused by uropathogenic Escherichia coli. Effective antimicrobial treatment of infections are medical achievements that should not be taken for granted, as antimicrobial resistance has developed and causes treatments to become ineffective. Further, resistance traits can be spread between unrelated ...