Now showing items 4961-4980 of 5637

    • Studie av klinisk relevans av forskrivningsavvik ved resepter utskrevet av sykehusleger 

      Erdal, Hilde (Master thesis; Mastergradsoppgave, 2008-05)
      Innledning: Apotekloven slår fast at legemidler skal utleveres nøyaktig etter resept og rekvisisjon. Studier viser imidlertid at feil og mangler forekommer ved 2,0 % av reseptene som blir levert inn ved vanlige apotek i Norge, og forskrivningsavvik forekommer ved 8,5 % av ordinasjonene på resepter utskrevet av leger ved Haukeland Universitetssykehus. Forskrivningsavvik kan medføre fare for klinisk ...
    • Studie av prehospitalt forløp hos pasienter med sepsis 

      Antonsen, Linn-Kristin (Master thesis; Mastergradsoppgave, 2014-07-31)
      Bakgrunn: Sepsis er en potensielt livstruende følgetilstand etter infeksjon. En rekke studier etter årtusenskiftet har vist at tidlig antibiotika- og væskebehandling øker overlevelsen av sepsis. I mars 2010 ble det innført nye retningslinjer for identifisering og håndtering av pasienter med sepsis i akuttmottaket ved UNN Tromsø. Vi vet lite om hva som skjer med sepsis-pasientene før de kommer til ...
    • Studielån på Blå Rock 

      Klausen, Rita Kristin (Journal article; Tidsskriftartikkel, 2017)
    • Studiemiljøet ved medisinstudiet ved UiT Norges arktiske universitet. Et tverrsnittsstudie ved bruk av The Dundee Ready Educational Environment Measure 

      Hamnes, Skjalg Erlend (Master thesis; Mastergradsoppgave, 2018-06-03)
      Bakgrunn: Et godt studiemiljø har vist seg å være viktig for god læring i utdanninger generelt, inkludert medisinutdanningen. Viktigheten av studiemiljøets effekt på god læring har ført til et behov for å måle utdanningers studiemiljø. Et verktøy som i flere studier har vært nyttig for å måle studiemiljøet innenfor medisinutdanningen er The Dundee Ready Educational Environment Meassure (DREEM). ...
    • Studier av mekanismer for subcellulær lokalisering av transkripsjonsfaktoren FoxO3a og regulering av FoxO3a-mediert transkripsjon 

      Christensen, Andreas Aleksander (Master thesis; Mastergradsoppgave, 2012-05-20)
      Lokalisering av FoxO transkripsjonsfaktorer reguleres av posttranslasjonelle modifikasjoner (PTM) som involverer fosforylering, ubiquitinering, acetylering og deacetylering. Disse modifikasjonene har betydning for subcellulær lokalisering av FoxO3a som videre kan regulere cellesyklus arrest, apoptose og autofagi. I tillegg spiller FoxO transkripsjonsfaktorer en viktig rolle for utvikling av kreft, ...
    • Studies in pathways to care - duration of untreated psychosis and its determining factors in early psychosis 

      Kvig, Erling Inge (Doctoral thesis; Doktorgradsavhandling, 2018-11-23)
      Mange pasienter med en førstegangspsykose får behandling sent i forløpet og har en lang varighet av ubehandlet psykose (VUP). Forsinket behandling kan skyldes både indre (lidelse og pasient relaterte) og ytre (tjeneste og systemrelaterte) faktorer. Til tross for at nyere forskning har dokumentert at en stor del av forsinkelsen skjer mens pasienten mottar behandling i spesialisthelsetjenesten, så er ...
    • Studies of genes potentially involved in the induction of flowering in Festuca pratensis (Huds.) 

      Henriksen, Hanne F. (Master thesis; Mastergradsoppgave, 2006-06-08)
      Many plants in northern regions require a period of low temperatures and short days (called vernalisation) during the winter season to initiate the flowering process. In this experiment, some genes thought to be involved in vernalisation response and induction of flowering in meadow fescue (Festuca pratensis) has been investigated. The genes were chosen based on their possible contribution in the ...
    • Studies of peripheral nerve blocks for hand and shoulder surgery 

      Flohr-Madsen, Sandra (Doctoral thesis; Doktorgradsavhandling, 2019-04-04)
      Performing regional anesthesia with a minimum effective volume (MEV) of local anesthetic may reduce the risk of systemic local anesthesia toxicity. The lateral sagittal infraclavicular block (LSIB) is a well-established anesthesia method for surgery distal to the shoulder. For LSIB using ropivacaine 7.5 mg/ml the MEV was previously not known and we estimated MEV95 to be 31 ml (95% CI, 18 – 45 ...
    • Studies of sociosexual interactions in rats in an externally valid procedure: Are they relevant for understanding human sexual behavior? 

      Chu, Xi; Ågmo, Anders j (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05)
      When a prolonged observation of groups of rats in a seminatural environment is used as testing procedure, different behavioral patterns are shown compared with what observed in a pair housed in a small cage. Males and females copulate simultaneously, they show a promiscuously and random copulatory pattern. Females remain completely receptive from the first lordosis displayed in the period of behavioral ...
    • A study of changes in glucose metabolism and inflammatory markers in morbidly obese patients undergoing bariatric surgery 

      Nestvold, Torunn Kristin (Doctoral thesis; Doktorgradsavhandling, 2015-06-08)
      Summary Obesity is considered a worldwide pandemic. Morbidly obese patients are at risk of developing comorbidity such as diabetes mellitus type 2, hypertension and cardiovascular disease. The mechanisms behind the development of such complications in morbidly obese patients are still not fully understood, but low-grade inflammation and visceral adiposity are both involved. Effective treatment that ...
    • A study of Fez1 and Fez2. Establishment of Fez1 and Fez2 knock out cells lines. Localization of Fez1 and Fez2 

      Nguyen, Jenny Thuy Tien (Master thesis; Mastergradsoppgave, 2017-05-16)
      Autophagy is an essential cellular process that is important to maintain homeostasis by degrading proteins, lipids and organelles during critical times like cellular or environmental stress conditions. Autophagy plays a critical role in human pathologies, since defective autophagy can lead to diseases like cancer, neurodegenerative- and inflammatory diseases. Fez1 (Fasciculation and elongation protein ...
    • A study of Fez1 and Fez2: Localization and knock-out 

      Schäfer, Helene Bekkeli (Master thesis; Mastergradsoppgave, 2016-05-11)
      Autophagy is a fundamental cellular process where cell components get digested in autolysosomes and are recycled. Dysregulation of autophagy is involved in major diseases like cancer, neurodegeneration, inflammation and ischemia. In this thesis we have worked with fasciculation and elongation zeta (Fez) proteins, which are reported to inhibit autophagy. There are at least two mammalian Fez proteins, ...
    • A study of fish consumption and cardiometabolic risk factors among the circumpolar population of the rural Nenets Autonomous Area in comparison with the urban population of Arkhangelsk County 

      Petrenya, Natalia (Doctoral thesis; Doktorgradsavhandling, 2012-12-14)
      Russia is a country with a high level of cardiovascular diseases (CVD) death. The nation has experienced several economic crises after the dissolution of the Soviet Union in 1991. While CVD-related deaths have decreased in Japan, North America and Western Europe during recent decades, CVD deaths in Russia have increased. Fish consumption is believed to have cardio-protective effects. Fish consumption ...
    • Study of interaction between BK virus large T-antigen and agnoprotein 

      Adou, Koman Mireille Sophie Chinan (Master thesis; Mastergradsoppgave, 2011-08)
      Human polyomavirus BK (BKV) is a non enveloped virus with a double-stranded, circular DNA genome. BKV infects >70% of the human population world-wide. Infection occurs predominantly during childhood and the virus remains in a latent state throughout life in the immune competent individuals. In the context of immunosuppression, however, reactivation occurs and can lead to renal stenosis and interstitial ...
    • A study of patient pharmaceutical care needs assessment in chronic obstructive pulmonary disease; as an example of a multidisciplinary intervention to reduce hospital re-admission in long term conditions 

      Skogly, Stian (Master thesis; Mastergradsoppgave, 2009-05-20)
      Introduction — The aim of Edinburgh Improved Anticipatory Care and Treatment (IMPACT) service is to reduce admissions and re-admissions to hospital for people with LTCs. The service consists of nurse case managers co-ordinating patients’ care, including reviewing medication. As a pilot project, an arrangement was made to refer such patients to a team of primary care pharmacists for clinical medication ...
    • A study of pharmaceutical care needs assessment in heart failure; to illustrate a multidisciplinary intervention to reduce hospital re-admissions in people with long term conditions 

      Berg, Camilla Torset (Mastergradsoppgave; Master thesis, 2009-05)
      Introduction The Edinburgh IMPACT (Improved Anticipatory Care and Treatment) is aimed at people with long term conditions, and focuses on improving patients’ quality of life and reducing preventable hospital admissions. The service is nurse led, and recently primary care pharmacists have been added to the team to perform a medication review pilot. Patients would be referred to the pharmacist, who ...
    • A study of possible genetic causes of inherited breast and ovarian cancer in a Norwegian cancer population 

      Jarhelle, Elisabeth (Master thesis; Mastergradsoppgave, 2013-05-15)
      Homologous recombination repair (HRR) is an important repair mechanism, and mutations disrupting the function of this machinery might contribute to cancer formation. Several proteins interact in this mechanism, and the two best known are BRCA1 and BRCA2. Mutations in their corresponding genes BRCA1 and BRCA2 are found in 40% of hereditary breast and ovarian cancer cases. However, there are still ...
    • A study of regulatory small RNAs in Vibrio salmonicida: construction of a knock-out mutant and a cDNA library 

      Nyrud, May Liss Julianne (Master thesis; Mastergradsoppgave, 2008-06-01)
      The marine fish pathogen Vibrio salmonicida is the causative agent for vibriosis in Atlantic salmon (Salmo salar L.), Rainbow trout (Oncorhynchus mykiss) and Atlantic cod (Gadus morhua L.). V. salmonicidas virulence is regulated by Quorum sensing (QS) systems, which includes important regulatory small RNAs (sRNAs). sRNAs have the last years been identified in large numbers, and mostly in pathogenic ...
    • A study of some biological factors of importance to geriatric psychiatry. 

      Grønli, Ole Kristian (Doctoral thesis; Doktorgradsavhandling, 2014-09-12)
      Det er lite kunnskap om vitamin D og sink mangel hos eldre med psykiske lidelser. I en case-control studie fant vi signifikant lavere serum nivå av 25(OH)D i en eldre (>64 år) pasient gruppe sammenlignet med en eldre kontroll gruppe (40.5 nmol/L vs. 65.9 nmol/L). Prevalens av vitamin D mangel (def: 25(OH) D<50 nmol/L) var 71.6% i pasient gruppen mot 20.0% i kontroll gruppen. Det var ikke forskjell ...
    • A study of the interaction between MAPKAP Kinase 5 / MK5 and DNAJB1 

      Lægreid, Kari Jenssen (Master thesis; Mastergradsoppgave, 2011-05-02)
      The mitogen activated protein kinases (MAPK) are a large and diverse family of protein kinases, contributing to the cells ability to respond to external stimuli by relaying messages in a well orchestrated way until they reach their final destinations. This is achieved through successive phosphorylation events. One member of this large family is mitogen activated protein kinase activated protein ...