Now showing items 5430-5449 of 5481

    • Whole-Blood Gene Expression Profiles in Large-scale Epidemiological Studies: What Do They Tell 

      Olsen, Karina Standahl; Skeie, Guri; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-08)
      In nutrigenomics, gene expression profiling is used to investigate transcriptional mechanisms associated with nutrients and diet. Blood samples collected in the framework of dietary interventions and epidemiological studies allow the use of humans as the model system, as opposed to using cell lines or animal models. Here, we review recent publications in the field of gene expression profiling, based ...
    • Whole-body vibrations associated with alpine skiing: A risk factor for low back pain? 

      Supej, Matej; Ogrin, Jan; Holmberg, Hans-Christer (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-09)
      Alpine skiing, both recreational and competitive, is associated with high rates of injury. Numerous studies have shown that occupational exposure to whole-body vibrations is strongly related to lower back pain and some suggest that, in particular, vibrations of lower frequencies could lead to overuse injuries of the back in connection with alpine ski racing. However, it is not yet known which ...
    • Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus heamolyticus in European hopsitals 

      Cavanagh, Jorunn Pauline; Hjerde, Erik; Holden, Matthew T.G.; Kahlke, Tim; Klingenberg, Claus; Flægstad, Trond; Parkhill, J; Bentley, Stephen D; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Whole-Organism Transcriptomic Analysis Provides Mechanistic Insight into the Acute Toxicity of Emamectin Benzoate in Daphnia magna 

      Song, You; Rundberget, Thomas; Evenseth, Linn Mari; Xie, Li; Gomes, Tania; Høgåsen, Tore; Iguchi, Taisen; Tollefsen, Knut Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-05)
      Emamectin benzoate (EMB) is an antisea lice chemical widely used in the aquaculture that may also unintentionally affect nontarget crustaceans in the environment. Although the adverse effects of this compound are well documented in various species, the full modes of action (MoAs) are still not well characterized. The current study was therefore conducted to characterize the MoAs of EMB and link ...
    • Why Bother to Participate? What Influences Student Motivation to Participate in Student Evaluations of Teaching (SET)? 

      Hoel, Anniken (Master thesis; Mastergradsoppgave, 2017-05-02)
      When response rates on student evaluation of teaching (SET) are low, the results cannot be interpreted as reliable and therefore not be used as intended. The low response rates, followed by departments inability to properly interpret responses from the students who do participate is a big problem. Where does the motivation to participate break down, and where and how does it make sense for the ...
    • Why do physicians lack engagement with smoking cessation treatment in their COPD patients? A multinational qualitative study 

      Van Eerd, Eva A.M.; Risør, Mette Bech; Spigt, Marcus; Godycki-Ćwirko, Maciek; Andreeva, Elena; Francis, Nick; Wollny, Anja; Melbye, Hasse; van Schayck, Onno; Kotz, Daniel (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-23)
      Smoking cessation is the only effective intervention to slow down the accelerated decline in lung function in smokers with chronic obstructive pulmonary disease. Nevertheless, physicians often do not routinely provide evidence-based smoking cessation treatment to their patients. To understand underlying reasons, we explored how physicians engage in smoking cessation treatment in their chronic ...
    • Why do women prefer home births in Ethiopia? 

      Shiferaw, Solomon; Spigt, Marcus; Godefrooij, Merijn; Melkamu, Yilma; Tekie, Michael (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Skilled attendants during labor, delivery, and in the early postpartum period, can prevent up to 75% or more of maternal death. However, in many developing countries, very few mothers make at least one antenatal visit and even less receive delivery care from skilled professionals. The present study reports findings from a region where key challenges related to transportation and ...
    • Why does the provision of home mechanical ventilation vary so widely? 

      Dybwik, Knut; Tollåli, Terje; Nielsen, Erik Waage; Brinchmann, Berit Støre (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      There is wide variation in the provision of home mechanical ventilation (HMV) throughout Europe, but the provision of home mechanical ventilation can also vary within countries. In 2008, the overall prevalence of HMV in Norway was 19.9/100,000, and there were huge regional differences in treatment prevalence. The aim of this study is to find explanations for these differences. We gathered ...
    • Why some women fail to give birth at health facilities: a qualitative study of women's perceptions of perinatal care from rural Southern Malawi 

      Kumbani, Lily C; Bjune, Gunnar Aksel; Chirwa, Ellen; Malata, Address; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Despite Malawi government’s policy to support women to deliver in health facilities with the assistance of skilled attendants, some women do not access this care. Objective: The study explores the reasons why women delivered at home without skilled attendance despite receiving antenatal care at a health centre and their perceptions of perinatal care. Methods: A descriptive study ...
    • Widespread hyperalgesia in adolescents with symptoms of irritable bowel syndrome: results from a large population-based study 

      Stabell, Niklas; Stubhaug, Audun; Flægstad, Trond; Mayer, Emeran; Naliboff, Bruce D; Nielsen, Christopher Sivert (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-06-03)
      Widespread hyperalgesia is well documented among adult patients with Irritable Bowel Syndrome (IBS), but little is known about pain sensitivity among adolescents with IBS. We examined pain sensitivity in 961 adolescents from the general population (mean age 16.1 years), including pain threshold and tolerance measurements of heat (forearm) and pressure pain (fingernail and shoulder), and ...
    • ‘Will I get cancer again?’ An ethnography of worries, healing landscapes and sensation-to-symptom processes among people living in the aftermath of cancer in rural Norway 

      Skowronski, Magdalena (Doctoral thesis; Doktorgradsavhandling, 2019-04-29)
      <p>Today, 71% of those who are diagnosed with cancer live five years or longer after treatment. Although the level of mortality varies considerably between different cancer diagnoses, the total number of people who recover after cancer is increasing. There is a need to gain knowledge on how people who live in the aftermath of cancer treatment experience health and illness, bodily sensations, everyday ...
    • Willingness and ability to pay for unexpected dental expenses by Finnish adults 

      Widström, Eeva; Seppälä, Timo (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Since 2002, adults have been able to choose oral health care services in the public sector or in the private sector in Finland. Though various subsidies for care exist in both sectors, the Public Dental Service (PDS) is a cheaper option for the patient but, on the other hand, there are no waiting lists for private care. The aim of this study was to assess middle-aged adults' use of dental services, ...
    • Within-population distribution of trimethoprim resistance in Escherichia coli before and after a community-wide intervention on trimethoprim use 

      Sundqvist, Martin; Granholm, Susanne; Naseer, Mohammed Umaer; Rydén, Patrik; Brolund, Alma; Sundsfjord, Arnfinn; Kahlmeter, Gunnar; Johansson, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance 

      Wickström, Malin; Dyberg, Cecilia; Milosevic, Jelena; Einvik, Christer; Calero, Raul; Sveinbjørnsson, Baldur; Sandén, Emma; Darabi, Anna; Siesjö, Peter; Kool, Marcel; Kogner, Per; Baryawno, Ninib; Johnsen, John Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-25)
      The DNA repair enzyme O6-methylguanine-DNA methyltransferase (MGMT) is commonly overexpressed in cancers and is implicated in the development of chemoresistance. The use of drugs inhibiting MGMT has been hindered by their haematologic toxicity and inefficiency. As a different strategy to inhibit MGMT we investigated cellular regulators of MGMT expression in multiple cancers. Here we show a ...
    • Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy 

      Abraityte, Aurelija; Lunde, Ida Gjervold; Askevold, Erik Tandberg; Michelsen, Annika E.; Christensen, Geir Arve; Aukrust, Pål; Yndestad, Arne; Fiane, Arnt; Andreassen, Arne; Aakhus, Svend; Dahl, Christen Peder; Gullestad, Lars; Broch, Kaspar; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-14)
      The Wingless (Wnt) pathway has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). To explore the role of Wnt modulators Wnt5a and sFRP3 in DCM patients we analyzed the expression of Wnt5a and sFRP3 in plasma and myocardium of DCM patients and evaluated their effects on NFAT luciferase activity in neonatal mouse cardiomyocytes. Elevated circulating Wnt5a (n = 102) was associated ...
    • Women with coronary heart disease – making sense of their symptoms and their experiences from interacting with their general practitioners 

      Gundersen, Agnes Erika Berg; Sørlie, Tore; Bergvik, Svein (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-01)
      Cardiovascular disease and particularly coronary heart disease (CHD) is the leading cause of death among women and men worldwide. CHD in women, and their symptoms and treatment trajectory are not well understood. Studies indicate gender-related differences in symptom presentation, comorbidity, help-seeking behavior, and the quality of diagnostics and treatment of CHD. Although the incidence ...
    • Women with fracture, unidentified by FRAX, but identified by cortical porosity, have a set of characteristics that contribute to their increased fracture risk beyond high FRAX score and high cortical porosity 

      Kral, Rita; Osima, Marit; Vestgaard, Roald; Richardsen, Elin; Bjørnerem, Åshild (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-25)
      The Fracture Risk Assessment Tool (FRAX) is widely used to identify individuals at increased risk for fracture. However, cortical porosity is associated with risk for fracture independent of FRAX and is reported to improve the net reclassification of fracture cases. We wanted to test the hypothesis that women with fracture who are unidentified by high FRAX score, but identified by high cortical ...
    • Women with type 2 diabetes mellitus have lower cortical porosity of the proximal femoral shaft using low-resolution CT than nondiabetic women, and increasing glucose is associated with reduced cortical porosity 

      Osima, Marit; Kral, Rita; Borgen, Tove Tveitan; Høgestøl, Ingvild Kristine; Joakimsen, Ragnar Martin; Eriksen, Erik Fink; Bjørnerem, Åshild (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-01)
      <p>Increased cortical porosity has been suggested as a possible factor increasing fracture propensity in patients with type 2 diabetes mellitus (T2DM). This is a paradox because cortical porosity is generally associated with high bone turnover, while bone turnover is reduced in patients with T2DM. We therefore wanted to test the hypothesis that women with T2DM have lower bone turnover markers (BTM) ...
    • Women’s reproductive health in the Sakha Republic (Yakutia) 

      Douglas, Natalia I; Pavlova, Tatiana U; Burtseva, Tatiana E; Rad, Yana G; Petrova, Palmira G; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • The wonderful aspects of Open Access publishing - and the unfortunate dark side. 

      Jokstad, Asbjørn (Journal article; Tidsskriftartikkel, 2015-03-10)