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    • Association of Achieving Lupus Low Disease Activity State Fifty Percent of the Time With Both Reduced Damage Accrual and Mortality in Patients With Systemic Lupus Erythematosus 

      Sharma, Chanakya; Raymond, Warren David; Eilertsen, Gro Østli; Nossent, Johannes (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-01)
      <i>Objective</i> - To assess the impact of achieving Lupus Low Disease Activity State ≥50% of the time (LLDAS‐50) on damage accrual and mortality in an inception cohort of patients with systemic lupus erythematosus (SLE).<p><p> <i>Methods</i> - We used data from the Tromsø Lupus Cohort, a longitudinal population‐based study of all patients with SLE in the 2 northernmost counties in Norway. ...

    • Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK 

      Bhaskaran, Krishnan; dos-Santos-Silva, Isabel; Leon, David A.; Douglas, Ian J.; Smeeth, Liam (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-30)
      <i>Background</i>: BMI is known to be strongly associated with all-cause mortality, but few studies have been large enough to reliably examine associations between BMI and a comprehensive range of cause-specific mortality outcomes.<p> <p><i>Methods</i>: In this population-based cohort study, we used UK primary care data from the Clinical Practice Research Datalink (CPRD) linked to national ...

    • Association of body mass index with COVID-19 related in-hospital death 

      Bouziotis, Jason; Arvanitakis, Marianna; Preiser, Jean-Charles; Abbas, Ali; Abdukahil, Sheryl Ann; Abdulkadir, Nurul Najmee; Abe, Ryuzo; Abel, Laurent; Absil, Lara; Acharya, Subhash; Acker, Andrew; Adachi, Shingo; Adam, Elisabeth; Adrião, Diana; Al Ageel, Saleh; Ahmed, Shakeel; Ain, Quratul; Ainscough, Kate; Aisa, Tharwat; Berdal, Jan-Erik; Dudman, Susanne Gjeruldsen; Dyrhol-Riise, Anne Ma; Skeie, Linda Gail; Heggelund, Lars; Hesstvedt, Liv; Holter, Jan Cato; Jenum, Synne; Johal, Simreen Kaur; Kildal, Anders Benjamin; Bekken, Gry Klouman; Lind, Andreas; Müller, Fredrik; Muller, Karl Erik; Pettersen, Frank O.; Paulsen, Else Quist; Reikvam, Dag Henrik; Holten, Aleksander Rygh; Skogen, Vegard; Stiksrud, Birgitte; Tonby, Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-29)
      Background: Patients with extreme body mass indices (BMI) could have an increased risk of death while hospitalized for COVID-19.<p> <p>Methods: The database of the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) was used to assess the time to in-hospital death with competing-risks regression by sex and between the categories of BMI. <p>Results: Data from 12,137 ...

    • Association of C-reactive protein with future development of diabetes: A population-based 7-year cohort study among Norwegian adults aged 30 and older in the Tromsø Study 2007-2016 

      Tong, Kit I; Hopstock, Laila Arnesdatter; Cook, Sarah (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-29)
      Objectives The extent to which observed associations between high-sensitivity C-reactive protein (hs-CRP) and incident diabetes are explained by obesity and hypertension remains unclear. This study aimed to investigate the association of hs-CRP with developing diabetes in a Norwegian general population sample.<p> <p>Design A cohort study using two population-based surveys of the Tromsø Study: ...

    • Association of circulating Vitamin D with colorectal cancer depends on Vitamin D-binding protein isoforms: A pooled, nested, case-control study 

      Gibbs, David Corley; Song, Mingyang; McCullough, Marjorie L.; Um, Caroline Y.; Bostick, Roberd M.; Wu, Kana; Flanders, W. Dana; Giovannucci, Edward; Jenab, Mazda; Brustad, Magritt; Tjønneland, Anne; Perez-Cornago, Aurora; Trichopoulou, Antonia; Tsilidis, Konstantinos K.; Hultdin, Johan; Gurrea, Aurelio Barricarte; Bueno-De-Mesquita, Bas; Mahamat-Saleh, Yahya; Kühn, Tilman; Gunter, Marc; Weiderpass, Elisabete; Fedirko, Veronika (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-15)
      <i>Background</i> - Higher circulating 25-hydroxyvitamin-D [25(OH)D] concentrations are consistently inversely associated with colorectal cancer (CRC) risk in observational studies. However, it is unknown whether this association depends on the functional GC-rs4588*A (Thr436Lys) variant encoding the vitamin D–binding protein-2 (DBP2) isoform, which may affect vitamin D status and bioavailability.< ...

    • The association of early post-transplant glucose levels with long term mortality 

      Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)

    • The association of education with body mass index and waist circumference in the EPIC-PANACEA study 

      Hermann, Silke; Rohrmann, Sabine; Linseisen, Jakob; May, Anne M.; Kunst, Anton; Besson, Herve; Romaguera, Dora; Travier, Noemie; Tormo, Maria-José; Molina, Esther; Dorronsoro, Miren; Barricarte, Aurelio; Rodriguez, Laudina; Crowe, Francesca L.; Khaw, Kay-Tee; Wareham, Nicholas J.; van Boeckel, Petra G.A.; Bueno-de-Mesquita, H. Bas; Overvad, Kim; Jakobsen, Marianne Uhre; Tjønneland, Anne; Halkjær, Jytte; Agnoli, Claudia; Mattiello, Amalia; Tumino, Rosario; Masala, Giovanna; Vineis, Paolo; Naska, Androniki; Orfanos, Philippos; Trichopoulou, Antonia; Kaaks, Rudolf; Bergmann, Manuela M.; Steffen, Annika; Van Guelpen, Bethany; Johansson, Ingegerd; Borgquist, Signe; Manjer, Jonas; Braaten, Tonje; Fagherazzi, Guy; Clavel-Chapelon, Françoise; Mouw, Traci; Norat, Teresa; Riboli, Elio; Rinaldi, Sabina; Slimani, Nadia; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      To examine the association of education with body mass index (BMI) and waist circumference (WC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). This study included 141,230 male and 336,637 female EPIC-participants, who were recruited between 1992 and 2000. Education, which was assessed by questionnaire, was classified into four categories; BMI and WC, measured by trained ...

    • Association of eGFR and mortality with use of a joint model: results of a nationwide study in Iceland 

      Jonsson, Arnar J; Lund, Sigrun H; Eriksen, Bjørn Odvar; Palsson, Runolfur; Indridason, Olafur S (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-09)
      Objectives. Prior studies on the association of estimated glomerular filtration rate (eGFR) and mortality have failed to include methods to account for repeated eGFR determinations. The aim of this study was to estimate the association between eGFR and mortality in the general population in Iceland employing a joint model.<p> <p>Methods. We obtained all serum creatinine and urine protein measurements ...

    • Association of Examination Rates with Children's National Caries Indices in Finland 

      Suominen-Taipale, AL; Widström, Eeva; Sund, R (Journal article; Tidsskriftartikkel, 2009)

    • Association of fatal myocardial infarction with past level of physical activity: a pooled analysis of cohort studies 

      Hansen, Kim Wadt; Peytz, Nina; Blokstra, Anneke; Bojesen, Stig E.; Celis-Morales, Carlos; Chrysohoou, Christina; Clays, Els; De Bacquer, Dirk; Galatius, Søren; Gray, Stuart R.; Ho, Frederick; Kavousi, Maryam; Koolhaas, Chantal M.; Kouvari, Matina; Løchen, Maja-Lisa; Marques-Vidal, Pedro; Osler, Merete; Panagiotakos, Demosthenes; Pell, Jill P.; Sulo, Gerhard; Tell, Grethe Seppola; Vassiliou, Vassilios; Verschuren, W.M. Monique; Prescott, Eva (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-10)
      <p>Aims: To assess the association between past level of physical activity (PA) and risk for death during the acute phase of myocardial infarction (MI) in a pooled analysis of cohort studies. <p>Methods and results: European cohorts including participants with a baseline assessment of PA, conventional cardiovascular (CV) risk factors, and available follow-up on MI and death were eligible. Patients ...

    • Association of glycated hemoglobin A1c levels with cardiovascular outcomes in the general population: results from the BiomarCaRE (Biomarker for Cardiovascular Risk Assessment in Europe) consortium 

      Sinning, Christoph; Makarova, Nataliya; Völzke, Henry; Schnabel, Renate B.; Ojeda, Francisco; Dörr, Marcus; Felix, Stephan B.; Koenig, Wolfgang; Peters, Annette; Rathmann, Wolfgang; Schöttker, Ben; Brenner, Hermann; Veronesi, Giovanni; Cesana, Giancarlo; Brambilla, Paolo; Palosaari, Tarja; Kuulasmaa, Kari; Njølstad, Inger; Mathiesen, Ellisiv B.; Wilsgaard, Tom; Blankenberg, Stefan; Söderberg, Stefan; Ferrario, Marco M.; Thorand, Barbara (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-15)
      Background: Biomarkers may contribute to improved cardiovascular risk estimation. Glycated hemoglobin A<sub>1c</sub> (HbA<sub>1c</sub>) is used to monitor the quality of diabetes treatment. Its strength of association with cardiovascular outcomes in the general population remains uncertain. This study aims to assess the association of HbA<sub>1c</sub> with cardiovascular outcomes in the general ...

    • The association of grip strength from midlife onwards with all-cause and cause-specific mortality over 17 years of follow-up in the Tromsø Study 

      Strand, Bjørn Heine; Cooper, Rachel; Bergland, Astrid; Jørgensen, Lone; Schirmer, Henrik; Skirbekk, Vegard; Emaus, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-08-25)
      <b>Background</b> Grip strength has consistently been found to predict all-cause mortality rates. However, few studies have examined cause-speci fi c mortality or tested age differences in these associations. <b>Methods</b> In 1994, grip strength was measured in the population-based Tromsø Study, covering the ages 50 – 80 years (N=6850). Grip strength was categorised into fi fths, and ...

    • Association of High-Density Lipoprotein Cholesterol With GFR Decline in a General Nondiabetic Population 

      Melsom, Toralf; Norvik, Jon Viljar; Enoksen, Inger Therese; Stefansson, Vidar Tor Nyborg; Rismo, Renathe; Jenssen, Trond; Solbu, Marit Dahl; Eriksen, Bjørn Odvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-18)
      <i>Introduction</i> - Although lower high-density lipoprotein cholesterol (HDL-C) levels are considered a risk factor for cardiovascular disease (CVD), experimental evidence suggest that aging, inflammation, and oxidative stress may remodel HDL-C, leading to dysfunctional HDL-C. Population studies on HDL-C and loss of the glomerular filtration rate (GFR) reported inconsistent results, but they used ...

    • Association of iron deficiency with incident cardiovascular diseases and mortality in the general population 

      Schrage, Benedict; Rübsamen, Nicole; Ojeda, Francisco; Thorand, Barbara; Peters, Annette; Koenig, Wolfgang; Söderberg, Stefan; Söderberg, Maja; Mathiesen, Ellisiv B.; Njølstad, Inger; Kee, Frank; Linneberg, Allan; Kuulasmaa, Kari; Palosaari, Tarja; Salomaa, Veikko; Blankenberg, Stefan; Zeller, Tanja; Karakas, Mahir (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-05)
      Aims - Although absolute (AID) and functional iron deficiency (FID) are known risk factors for patients with cardiovascular (CV) disease, their relevance for the general population is unknown. The aim was to assess the association between AID/FID with incident CV disease and mortality in the general population.<p> <p>Methods and results - In 12 164 individuals from three European population-based ...

    • Association of Klotho protein levels and KL-VS heterozygosity with Alzheimer disease and amyloid and tau burden 

      Grøntvedt, Gøril Rolfseng; Sando, Sigrid Botne; Lauridsen, Camilla; Bråthen, Geir; White, Linda Rosemary; Salvesen, Øyvind; Aarsland, Dag; Hessen, Erik; Fladby, Tormod; Waterloo, Knut K; Scheffler, Katja (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-22)
      Importance Identification of proteins and genetic factors that reduce Alzheimer disease (AD) pathology is of importance when searching for novel AD treatments. Heterozygosity of the KL-VS haplotype has been associated with reduced amyloid and tau burden. Whether this association is mediated by the Klotho protein remains unclear. Objectives To assess concentrations of Klotho in cerebrospinal ...

    • Association of lifetime indoor tanning and subsequent risk of cutaneous squamous cell carcinoma 

      Lergenmuller, Simon; Ghiasvand, Reza; Robsahm, Trude Eid; Green, Adele C.; Lund, Eiliv; Rueegg, Corina Silvia; Veierød, Marit Bragelien (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-02)
      <i>Importance</i> - No study, to our knowledge, has prospectively investigated a dose-response association between lifetime indoor tanning and risk of cutaneous squamous cell carcinoma (SCC).<p> <p><i>Objective</i> - To investigate the dose-response association between lifetime indoor tanning and SCC risk, the association between duration of use and age at initiation with SCC risk, and the ...

    • Association of lipid-lowering drugs and antidiabetic drugs with age-related macular degeneration: A meta-analysis in Europeans 

      Mauschitz, Matthias M.; Verzijden, Timo; Schuster, Alexander K.; Elbaz, Hisham; Pfeiffer, Norbert; Khawaja, Anthony; Luben, Robert N.; Foster, Paul J.; Rauscher, Franziska G.; Wirkner, Kerstin; Kirsten, Toralf; Jonas, Jost B.; Bikbov, Mukharram M.; Hogg, Ruth; Peto, Tunde; Cougnard-Grégoire, Audrey; Bertelsen, Geir; Erke, Maja Gran; Topouzis, Fotis; Giannoulis, Dimitrios A.; Brandl, Caroline; Heid, Iris M.; Creuzot-Garcher, Catherine P.; Gabrielle, Pierre-Henry; Hense, Hans-Werner; Pauleikhoff, Daniel; Barreto, Patricia; Coimbra, Rita; Piermarocchi, Stefano; Daien, Vincent; Holz, Frank G.; Delcourt, Cecile; Finger, Robert P. (Journal article; Tidsskriftartikkel, 2022-11-07)
      <p><i>Background/aims</i> To investigate the association of commonly used systemic medications with prevalent age-related macular degeneration (AMD) in the general population. <p><i>Methods</i> We included 38 694 adults from 14 population-based and hospital-based studies from the European Eye Epidemiology consortium. We examined associations between the use of systemic medications and any prevalent ...

    • Association of low-density lipoprotein cholesterol with risk of aortic valve stenosis in familial hypercholesterolemia 

      Mundal, Liv; Hovland, Anders; Igland, Jannicke; Veierød, Marit Bragelien; Holven, Kirsten Bjørklund; Bogsrud, Martin Prøven; Tell, Grethe S.; Leren, Trond Paul; Retterstøl, Kjetil (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-16)
      <i>Importance</i> - Aortic valve stenosis (AS) is the most common valve disease. Elevated levels of low-density lipoprotein (LDL) cholesterol are a risk factor; however, lipid-lowering treatment seems not to prevent progression of AS. The importance of LDL cholesterol in the development of AS thus remains unclear. People with familial hypercholesterolemia (FH) have elevated LDL cholesterol levels ...

    • Association of maternal SARS-CoV-2 infection at the time of admission for delivery with labor process and outcomes of vaginal birth: A cohort study 

      Chen, An; Acharya, Ganesh Prasad; Hu, Min; Gao, Xin; Cheng, Guizhi; Jiang, Lai; Ni, Qianqian (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-05)
      Introduction - This study aimed to investigate the impact of maternal SARS-CoV-2 infection at the time of admission for delivery on labor process and outcomes of vaginal birth.<p> <p>Material and methods - A cohort study was carried out at the Obstetrics Department of Anhui Provincial Hospital, China, where universal reverse transcriptase polymerase chain reaction (RT-PCR) testing for SARS-CoV-2 ...

    • Association of Mediterranean diet with survival after breast cancer diagnosis in women from nine European countries: results from the EPIC cohort study 

      Castro-Espin, Carlota; Bonet, Catalina; Crous-Bou, Marta; Nadal-Zaragoza, Núria; Tjønneland, Anne; Mellemkjær, Lene; Hajji-Louati, Mariem; Truong, Thérèse; Katzke, Verena; Le Cornet, Charlotte; Schulze, Matthias B.; Jannasch, Franziska; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Di Girolamo, Chiara; Skeie, Guri; Borch, Kristin Benjaminsen; Olsen, Karina Standahl; Sánchez, Maria-Jose; Amiano, Pilar; Chirlaque, María-Dolores; Guevara, Marcela; Sund, Malin; Bodén, Stina; Gunter, Marc J.; Gonzalez-Gil, Esther M.; Weiderpass, Elisabete; Aguilera-Buenosvinos, Inmaculada; Tsilidis, Kostas K.; Heath, Alicia K.; Aune, Dagfinn; Dossus, Laure; Agudo, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-26)
      Background - The Mediterranean diet has been associated with lower risk of breast cancer (BC) but evidence from prospective studies on the role of Mediterranean diet on BC survival remains sparse and conflicting. We aimed to investigate whether adherence to Mediterranean diet prior to diagnosis is associated with overall and BC-specific mortality.<p> <p>Methods - A total of 13,270 incident breast ...