Now showing items 13-32 of 6105

    • ABC-transportørenes kliniske betydning 

      Bremnes, Thomas (Master thesis; Mastergradsoppgave, 2013-06-02)
      Multi-legemiddelresistens (multidrug resistance, MDR) er resistens mot flere strukturelt uavhengige kjemoterapimidler. Dette er spesielt ett problem for behandling av kreft fordi kreftceller kan danne resistens mot flere midler samtidig. Slik resistens utvikles ved hjelp av flere cellulære mekanismer. Den mest undersøkte og oftest assosierte metoden er via økt uttrykk av ATP-bindende kassett ...
    • ABC-transportører 

      Slåtsve, Arne Martin (Mastergradsoppgave; Master thesis, 2009-09-15)
      ABC (ATP-binding cassette)-transportører er store, evolusjonsmessig høykonserverte membranproteiner som er påvist i alle arter fra prokaryoter til komplekse organismer. ABC-transportørene muliggjør energiavhengig transport av spesifikke substrater gjennom cellemembraner. Blant substratene vi kjenner er lipider, karbohydrater, peptider, vitaminer, steroidhormoner, xenobiotika og medikamenter. ...
    • ABCC9-related intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9 

      Smeland, Marie Falkenberg; McClenaghan, Conor; Roessler, Helen I.; Savelberg, Sanne; Hansen, Geir Åsmund Myge; Hjellnes, Helene; Arntzen, Kjell Arne; Müller, Kai Ivar; Dybesland, Andreas R.; Harter, Theresa; Sala-Rabanal, Monica; Emfinger, Chris H.; Huang, Yan; Singareddy, Soma S.; Gunn, Jamie; Wozniak, David F.; Kovacs, Attila; Massink, Maarten; Tessadori, Federico; Kamel, Sarah M.; Bakkers, Jeroen; Remedi, Maria S.; Van Ghelue, Marijke; Nichols, Colin G.; van Haaften, Gijs (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-01)
      Mutations in genes encoding K<sub>ATP</sub> channel subunits have been reported for pancreatic disorders and Cantú syndrome. Here, we report a syndrome in six patients from two families with a consistent phenotype of mild intellectual disability, similar facies, myopathy, and cerebral white matter hyperintensities, with cardiac systolic dysfunction present in the two oldest patients. Patients are ...
    • Abdominal aortic aneurysms, or a relatively large diameter of non-aneurysmal aortas, increase total and cardiovascular mortality: the Tromsø study. 

      Forsdahl, Signe Helene; Solberg, Steinar; Singh, Kulbir; Jacobsen, Bjarne Koster (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      Background: In a population-based study in Tromsø, Norway, the authors assessed whether an abdominal aortic aneurysm (AAA) or the maximal infrarenal aortic diameter in a non-aneurismal aorta influence total and cardiovascular disease (CVD) mortality. Methods: A total of 6640 men and women, aged 25–84 years, were included in a 10-year mortality follow-up: 345 subjects with a diagnosed AAA and ...
    • Abdominal symptoms in general practice: Frequency, cancer suspicions raised, and actions taken by GPs in six European countries. Cohort study with prospective registration of cancer 

      Holtedahl, Knut A.; Borgquist, Lars; Donker, Gé A.; Buntinx, Frank; Weller, David; Braaten, Tonje; Hjertholm, Peter; Månsson, Jörgen; Strandberg, Eva Lena; Campbell, Christine; Ellegaard, Lisbeth; Parajuli, Ranjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06)
      Background<br> Abdominal symptoms are diagnostically challenging to general practitioners (GPs): although common, they may indicate cancer. In a prospective cohort of patients, we examined abdominal symptom frequency, initial diagnostic suspicion, and actions of GPs in response to abdominal symptoms.<p> Methods<br> Over a 10-day period, 493 GPs in Norway, Denmark, Sweden, Belgium, the Netherlands, ...
    • The ability of the strengths and difficulties questionnaire to detect mental health disorders in a child and adolescent outpatient clinic in Northern-Norway 

      Sæther, Guri; Moe, Therese Fjeldmo (Master thesis; Mastergradsoppgave, 2010-05-03)
      The aim of the study was to examine the ability of the Strength and Difficulties Questionnaire (SDQ) to detect mental health disorders among patients referred to a child and adolescent outpatient clinic. The sample consisted of 100 participants between 5 and 17 years referred to an outpatient clinic in Northern-Norway. The SDQ-generated diagnostic predictions were compared to a gold standard to ...
    • Abort i andre trimester. Ei femårig retrospektiv studie 

      Skjeldal, Hege (Master thesis; Mastergradsoppgave, 2006)
    • Abridged risk information: Effects of warning labels on snus packages 

      Nilsen, Connie Villemo (Doctoral thesis; Doktorgradsavhandling, 2020-02-28)
      <i>Background</i> - We screened the sparse literature on how health warnings on snus products affect risk perception and use intentions, and contributed with two experimental studies on the topic.<p> <p><i> Methods</i> - First, we examined previous studies on health warnings on smokeless tobacco in a systematic review, studied the manipulations in exposure studies, and systematized the outcome ...
    • Absentee rates in physical education in high schools: The importance of gender and study programmes 

      Lagestad, Pål Arild; Welde, Boye; Rånes, Vebjørn; Myhre, Hege (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-02)
      Little is known about absenteeism in high school physical education (PE) in relation to study programme and gender. This study investigated the impact of gender and study programme on absentee rates in PE by analyzing data, using non-parametric statistical analyses, from the absentee registers for all 6928 students in Nordland Country. The results showed that the absentee rates in PE differed among ...
    • Academic detailing as a method of continuing medical education 

      Dyrkorn, Roar; Langaas, Harald Chr.; Giverhaug, Trude; Espnes, Ketil Arne; Rowett, Debra; Spigset, Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
      <i>Introduction</i>: Academic detailing is an interactive educational outreach to prescribers to present unbiased, non-commercial, evidence-based information, mostly about medications, with the goal of improving patient care. Academic detailing in Norway is an approach for providing continuing medical education to general practitioners (GPs). The basis of academic detailing is a one-to-one discussion ...
    • Academic performance and student dropout. Results from two studies in upper secondary and higher education in Northern Norway 

      Sæle, Rannveig Grøm (Doctoral thesis; Doktorgradsavhandling, 2016-08-19)
      Education is important for the individual and for society. One of the most important and stable predictors of educational dropout is academic performance, typically measured by grades. This thesis aims to investigate factors related to academic performance and student dropout. It comprises two projects. The first project, Young Will (Ung vilje), is based on a sample of adolescents entering upper ...
    • Accelerations and high intensity running in field and assistant football referees during match play 

      Riiser, Amund; Pettersen, Svein Arne; Andersen, Vidar; Sæterbakken, Atle Hole; Frøyd, Christian; Ylvisåker, Einar; Moe, Vegard Fusche (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-20)
      <p><i>Objectives</i>: (1) to examine accelerations and high intensity running (HIR) in football field referees (FR) and assistant referees (AR) during football matches and (2) to evaluate fluctuations in accelerations and HIR between first and second half and in 5-min periods.</p> <p><i>Methods</i>: All movements of the referees were measured using a radio-based tracking system during 41 matches ...
    • Acceptability of an mHealth app intervention for persons with type 2 diabetes and its associations with initial self-management: Randomized controlled trial 

      Torbjørnsen, Astrid; Småstuen, Milada Cvancarova; Jenum, Anne Karen; Årsand, Eirik; Ribu, Lis (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-21)
      <p><i>Background</i>: Mobile health interventions are increasingly used in health care. The level of acceptability may indicate whether and how such digital solutions will be used.</p> <p><i>Objective</i>: This study aimed to explore associations between the level of acceptability of a mobile diabetes app and initial ability of self-management for patients with type 2 diabetes.</p> <p><i>Methods</i>: ...
    • Acceptability, feasibility, and cost of telemedicine for nonacute headaches: A randomized study comparing video and traditional consultations 

      Müller, Kai Ivar; Alstadhaug, Karl Bjørnar; Bekkelund, Svein Ivar (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-30)
      <b>Backgr ound:</b> The feasibility of telemedicine in diagnosing and treating nonacute headaches, such as primary headaches (migraine and tension-type) and medication-overuse headaches has not been previously investigated. By eliminating the need of travel to specialists, telemedicine may of fer significant time and money ...
    • Acceptance and commitment theraphy og kroniske smerter i allmennpraksis 

      Pettersen, Kristian (Master thesis; Mastergradsoppgave, 2013-06-02)
      Kronisk smerte er definert som smerte med varighet på 6 måneder eller mer. Kortvarig smerte behandles vanligvis med medikamentell smertelindring, mens en tverrfaglig tilnærming til kroniske smerter har best effekt. Den tverrfaglige behandlingen skjer oftest ved smerteklinikker, og består av ulike former for Cognitive Behavioral Therapy (CBT). De senere årene har det kommet en ny bølge av psykoterapeutiske ...
    • Accidental hypothermia - A review on the underlying physiological and pathophysiological mechanisms and treatment of accidental hypothermia 

      Håheim, Brage (Master thesis; Mastergradsoppgave, 2014-06-01)
      Accidental hypothermia is a rare condition with few deaths per year, but hypothermic patients have a 30% chance of dying. The past 15-20 years there has been an increased understanding of how hypothermia affects human physiology and may cause life-threatening conditions like arrhythmias, cardiovascular shock and pulmonary edema. New understanding of underlying mechanisms of hypothermia- induced ...
    • Acculturation : early political and social science conceptions 

      Rudmin, Floyd Webster (Preprint; Manuskript, 2003-10)
    • Acculturation alchemy : how miscitations make biculturalism appear beneficial 

      Rudmin, Floyd Webster (Journal article; Tidsskriftartikkel, 2007)
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    • Acculturation and self-rated health among Arctic indigenous peoples : a population-based cross-sectional study 

      Eliassen, Bent-Martin; Braaten, Tonje; Melhus, Marita; Hansen, Ketil Lenert; Broderstad, Ann Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Acculturation is for indigenous peoples related to the process of colonisation over centuries as well as the on-going social transition experienced in the Arctic today. Changing living conditions and lifestyle affect health in numerous ways in Arctic indigenous populations. Self-rated health (SRH) is a relevant variable in primary health care and in general public health assessments and monitoring. ...
    • Accumulation of stable full-length circular group i intron RNAs during heat-shock 

      Andersen, Kasper L.; Beckert, Bertrand; Masquida, Benoît; Johansen, Steinar Daae; Nielsen, Henrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-31)
      Group I introns in nuclear ribosomal RNA of eukaryotic microorganisms are processed by splicing or circularization. The latter results in formation of full-length circular introns without ligation of the exons and has been proposed to be active in intron mobility. We applied qRT-PCR to estimate the copy number of circular intron RNA from the myxomycete Didymium iridis . In ...