Now showing items 3969-3988 of 6105

    • O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes 

      Barkovskaya, Anna; Seip, Kotryna; Hilmarsdòttir, Bylgja; Mælandsmo, Gunhild Mari; Moestue, Siver Andreas; Itkonen, Harri (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-05)
      Post-translational modifcation of intracellular proteins with a single N-acetylglucosamine sugar (O-GlcNAcylation) regulates signaling, proliferation, metabolism and protein stability. In breast cancer, expression of the enzyme that catalyzes O-GlcNAcylation – O-GlcNAc-transferase (OGT), and the extent of protein O-GlcNAcylation, are upregulated in tumor tissue, and correlate with cancer progression. ...
    • Obduksjoner. Er de nødvendige som kvalitetskontroll ved et moderne universitetssykehus? 

      Clausen, Vegard H. (Master thesis; Mastergradsoppgave, 2003-09-04)
    • Obesity and obesity-associated cardiometabolic risk factors in indigenous Nenets women from the rural Nenets Autonomous Area and Russian women from Arkhangelsk city 

      Petrenya, Natalia; Brustad, Magritt; Dobrodeeva, Lilya; Bichkaeva, Fatima; Lutfalieva, Gulnara; Cooper, Marie; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Obesity and Staphylococcus aureus Nasal Colonization among Women and Men in a General Population 

      Olsen, Karina; Danielsen, Kjersti; Wilsgaard, Tom; Sangvik, Maria; Sollid, Johanna U. Ericson; Thune, Inger; Eggen, Anne Elise; Simonsen, Gunnar Skov; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Obesity and diabetes mellitus (DM) have been linked to increased risk of infections, and Staphylococcus aureus nasal colonization is a major risk factor for developing infections with the microbe. We therefore sought to find whether body mass index (BMI) and waist circumference (WC) could be associated with S. aureus colonization independent of DM. Methodology: S. aureus colonization ...
    • Obesity at age 20 and the risk of miscarriages, irregular periods and reported problems of becoming pregnant: the Adventist Health Study-2. 

      Jacobsen, Bjarne Koster; Knutsen, Synnøve Fønnebø; Oda, Keiji; Fraser, Gary E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      In a group of 46,000 North-American Adventist women aged 40 and above, we investigated the relationships between body mass index (BMI, kg/m2) at age 20 and the proportion of women who reported at least one miscarriage, periods with irregular menstruation or failing to become pregnant even if trying for more than one straight year. Approximately 31, 14 and 17 %, respectively, reported the three ...
    • Obesity measures and risk of venous thromboembolism and myocardial infarction 

      Horvei, Lars Daae; Brækkan, Sigrid Kufaas; Mathiesen, Ellisiv B.; Njølstad, Inger; Wilsgaard, Tom; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Obesity, body height and risk of venous thromboembolism 

      Horvei, Lars Daae (Doctoral thesis; Doktorgradsavhandling, 2018-01-18)
      Venous thromboembolism (VTE) is a collective term for deep vein thrombosis (DVT) and pulmonary embolism (PE). Obesity, as well as a tall stature, are well-known and substantial risk factors for VTE, but the underlying mechanisms behind these associations are not fully understood. The aims of this thesis were to investigate how different patterns of body fat distribution, levels of obesity-related ...
    • Obesity, renal hyperfiltration and glomerular filtration rate decline in the general population 

      Stefansson, Vidar Tor Nyborg (Doctoral thesis; Doktorgradsavhandling, 2019-06-11)
      Obesity is a well-known risk factor for several severe diseases, including diabetes and cardiovascular disease. The metabolic syndrome is a concept related to obesity which includes additional risk factors for disease: increased waist circumference, high blood pressure, elevated fasting glucose, elevated triglycerides and lowered high-density lipoprotein cholesterol levels. Both obesity and the ...
    • Obesity-related cardiovascular risk factors after weight loss : a clinical trial comparing gastric bypass surgery and intensive lifestyle intervention 

      Hofsø, Dag; Nordstrand, Njord; Johnson, Line Kristin; Karlsen, Tor-Ivar; Hager, Helle; Jenssen, Trond Geir; Bollerslev, Jens; Godang, Kristin; Sandbu, Rune; Røislien, Jo; Hjelmesæth, Jøran (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      Objective: Weight reduction improves several obesity-related health conditions. We aimed to compare the effect of bariatric surgery and comprehensive lifestyle intervention on type 2 diabetes and obesityrelated cardiovascular risk factors. Design: One-year controlled clinical trial ( identifier NCT00273104). Methods: Morbidly obese subjects (19–66 years, mean (S.D.) body mass ...
    • Object tracking for improved telementoring and telestration 

      Fatiev, Dmitry (Master thesis; Mastergradsoppgave, 2015-05-15)
      Telementoring in image-guided surgery has long since become a worldwide trend, facilitating faster and better surgical expertise distribution, increased quality of learning for beginner surgeons and better clinical outcomes for patients who no longer have to wait for an expert to travel (or do not have to travel themselves). Since the early days of telementoring, telestration (freehand annotation) ...
    • An observational study of compliance with the Scandinavian guidelines for management of minimal, mild and moderate head injury. 

      Heskestad, Ben Ottar; Waterloo, Knut; Ingebrigtsen, Tor; Romner, Bertil; Harr, Marianne Efskind; Helseth, Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The Scandinavian guidelines for management of minimal, mild and moderate head injuries were developed to provide safe and cost effective assessment of head injured patients. In a previous study conducted one year after publication and implementation of the guidelines (2003), we showed low compliance, involving over-triage with computed tomography (CT) and hospital admissions. The aim of the present ...
    • Observed communication skills: how do they relate to the consultation content? A nation-wide study of graduate medical students seeing a standardized patient for a first-time consultation in a general practice setting 

      Anvik, Tor; Nordøy, Tone; Gude, Tore; Vaglum, Per; Bærheim, Anders; Eide, Hilde; Fasmer, Ole B.; Gravgaard, Peter; Grimstad, Hilde; Hjortdahl, Per; Holen, Are; Skirbekk, Helge; Finset, Arnstein (Journal article; Tidsskriftartikkel; Peer reviewed, 2007-11-08)
      Background: In this study, we wanted to investigate the relationship between background variables, communication skills, and the bio-psychosocial content of a medical consultation in a general practice setting with a standardized patient. Methods: Final-year medical school students (N = 111) carried out a consultation with an actor playing the role of a patient with a specific somatic complaint, ...
    • Obsessiv-kompulsiv lidelse hos barn og unge og behandling, med hovedvekt på kognitiv atferdsterapi 

      Fosseide, Ida Henriette Henningsen (Master thesis; Mastergradsoppgave, 2011-09-15)
      Litteraturstudium som tar for seg tvangslidelse (OCD) hos barn og unge, og behandling av lidelsen ved hjelp av kognitiv terapi. OCD er karakterisert av plagsomme tvangstanker og/eller tvangshandlinger. Det kliniske bildet varierer mye fra pasient til pasient og hos samme pasient over tid. Rundt 2 prosent av barn og voksne har sykdommen. Mange får sykdommen i barne- eller ungdomsårene. For de som er ...
    • Obstacles for child participation in care and protection cases : why Norwegian social workers find it difficult 

      Vis, Svein Arild; Holtan, Amy; Nigel, Thomas (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Although some attempts are being made to increase children's participation in Norwegian child protection cases, much needs to be done in order to comply with the participation principle in the United Nations Convention on the Rights of the Child. This paper reports on a study of factors that are likely to predict if social workers will attempt to give children an effective voice in decision making ...
    • Obstetric anal sphincter injuries : risk factors, episiotomy characteristics, and pelvic floor dysfunction 

      Stedenfeldt, Mona (Doctoral thesis; Doktorgradsavhandling, 2013-11-14)
      Obstetric anal sphincter injuries (OASIS) are well known and serious complications of vaginal delivery. The incidence in Norway increased from below 1.0% in the 1960s to 4.3% in 2004. As a consequence a national strategy to reduce the number of OASIS was initiated by the Directorate for Health and Social affairs/National Advisory Committee for Obstetrics. As a part of this strategy an interventional ...
    • Obstetriske pasienter transportert med ambulansehelikopteret i Troms mai 1999 - desember 2003. 

      Jensen, Kristin; Ringstad, Mona-Helen; Lindemann, Kristine Opheim (Master thesis; Mastergradsoppgave, 2004-09-15)
    • "Obstipasjon - et økende problem hos barn?" 

      Karlsen, Aksel Zahl (Master thesis; Mastergradsoppgave, 2016-06-01)
      Formål Barneleger ved sykehus mener at de ser en økning i antall innleggelser for forstoppelse nå, enn tidligere. Vi ønsket å se om dette stemmer. Ut fra journalopplysninger ønsket vi også å se om anamneseopptak og kliniske undersøkelser som er gjort på barna innlagt med diagnosen ”K59.0 Forstoppelse”, er kvalitetsmessig gode nok for å forsvare diagnosen. Metode For å finne ut om det var flere ...
    • Occupation and relative risk of cutaneous squamous cell carcinoma (cSCC). A 45-year follow-up study in 4 Nordic countries 

      Alfonso, Jose Hernan; Martinsen, Jan Ivar; Pukkala, Eero; Weiderpass, Elisabete; Tryggvadottir, Laufey; Nordby, Karl-Christian; Kjærheim, Kristina (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09)
      Background The age-adjusted incidence of cutaneous squamous cell carcinoma (cSCC) in the Nordic countries has increased during the last 60 years, and the identification of occupational variation in the relative risk of cSCC may have preventive implications. Objective We sought to describe variation in the relative risk of cSCC between occupational categories in Finland, Iceland, Norway, and ...
    • Occupational accidents in Russia and the Russian Arctic 

      Dudarev, AA; Karnachev, Igor P; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background. According to official statistics, the rate of occupational accidents (OAs) and fatal injuries in Russia decreased about 5-fold and 2-fold, respectively, from 1975 to 2010, but working conditions during this period had the opposite trend; for example, the number of people who work in unfavourable and hazardous conditions (particularly since 1991) has increased significantly. Methods. ...