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    • S100A8 gene copy number and protein expression in breast cancer: associations with proliferation, histopathological grade and molecular subtypes 

      Børkja, Mathieu; Giambelluca, Miriam Soledad; Ytterhus, Borgny; Prestvik, Wenche Slettahjell; Bjørkøy, Geir; Bofin, Anna M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-14)
      Background and aims Amplification of S100A8 occurs in 10–30% of all breast cancers and has been linked to poorer prognosis. Similarly, the protein S100A8 is overexpressed in a roughly comparable proportion of breast cancers and is also found in infiltrating myeloid-lineage cells, again linked to poorer prognosis. We explore the relationship between these findings.<p> <p>Methods We examined S100A8 ...

    • Sacral neuromodulation and injection of bulking agents for faecal incontinence and concomitant pelvic floor dysfunction 

      Rydningen, Mona Birgitte (Doctoral thesis; Doktorgradsavhandling, 2017-05-12)
      Aim: The overall aim of the PhD thesis was to investigate different aspects of treatment with sacral neuromodulation (SNM) and injection of bulking agents (Permacol®) for faecal incontinence (FI) and concomitant pelvic floor dysfunction in women with a history of obstetric anal sphincter injuries (OASIS). <p>Method: Consecutive women with severe FI following OASIS after failure of conservative ...

    • Safe Blood Transfusion: Screening for Hepatitis B and Hepatitis C Virus Infections in Potential Blood Donors in Rural Southeast Asia 

      Le, Viet (Doctoral thesis; Doktorgradsavhandling, 2014-11-06)
      2,400 blood samples from potential voluntary rural blood donors in a multicentre cross-sectional study in Cambodia and Vietnam were analysed with rapid and EIA tests for detection of HBsAg, anti-HBc and anti-HCV at local laboratories. 640 randomly selected blood samples were blindly validated in a Norwegian accredited micro-laboratory by a chemiluminescent micro particle immunoassay technique (CMIA). ...

    • Safe Surgery Checklist, Patient Safety, teamwork, and Responsibility - Coequal Demands? A Focus Group Study 

      Willassen, Elin Thove; Smith Jacobsen, Inger Lise; Tveiten, Sidsel (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-28)
      The use of World Health Organization’s (WHO’s) Safe Surgery checklist is an established practice worldwide and contributes toward ensuring patient safety and collaborative teamwork. The aim of this study was to elucidate operating room nurses’ and operating room nursing students’ experiences and opinions about execution of and compliance with checklists. We chose a qualitative design with semistructured ...

    • Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial. 

      Roaldsen, Melinda Berg; Eltoft, Agnethe; Wilsgaard, Tom; Christensen, Hanne; Engelter, Stefan T.; Indredavik, Bent; Jatužis, Dalius; Karelis, Guntis; Kõrv, Janika; Lundström, Erik; Petersson, Jesper; Putaala, Jukka; Søyland, Mary-Helen; Tveiten, Arnstein; Bivard, Andrew; Johnsen, Stein Harald; Mazya, Michael; Werring, David J; Wu, Teddy Y; de Marchis, Gian Marco; Robinson, Thompson G; Mathiesen, Ellisiv B (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-19)
      Background - Current evidence supports the use of intravenous thrombolysis with alteplase in patients with wake-up stroke selected with MRI or perfusion imaging and is recommended in clinical guidelines. However, access to advanced imaging techniques is often scarce. We aimed to determine whether thrombolytic treatment with intravenous tenecteplase given within 4·5 h of awakening improves functional ...

    • Safety and efficiency of a new generic package labelling: A before and after study in a simulated setting 

      Garcia, Beate Hennie; Elenjord, Renate; Bjørnstad, Camilla Hilda; Halvorsen, Kjell H.; Hortemo, Sigurd; Madsen, Steinar (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-20)
      Background: Medication errors are frequent and may cause harm to patients and increase healthcare expenses. <p> Aim: To explore whether a new labelling influences time and errors when preparing medications in accordance with medication charts in an experimental setting. <p> Method: We carried out an uncontrolled before and after study with 3 months inbetween experiments. Phase I used original ...

    • Safety and Outcomes of Tenecteplase in Moderate and Severe Ischemic Stroke. Results From NOR-TEST 

      Kvistad, Christopher Elnan; Novotny, Vojtech; Kurz, Martin; Rønning, Ole M.; Thommessen, Bente; Carlsson, Maria; Waje-Andreassen, Ulrike; Næss, Halvor; Thomassen, Lars; Logallo, Nicola (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-08)
      <p><i>Background and Purpose — </i>Tenecteplase represents a promising alternative to alteplase as thrombolytic treatment in acute ischemic stroke. There are limited data on tenecteplase 0.4 mg/kg in patients with increased stroke severity. We aimed to assess safety and efficacy of tenecteplase 0.4 mg/kg in patients with moderate and severe ischemic stroke. <p><i>Methods — </i>NOR-TEST (Norwegian ...

    • Safety and use of complementary and alternative medicine in Norway during the first wave of the COVID-19 pandemic using an adapted version of the I-CAM-Q; a cross-sectional survey 

      Kristoffersen, Agnete Egilsdatter; Jong, Miek; Esther T., van der Werf; Hök, Johanna; Stub, Trine (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-03)
      Background: The COVID-19 pandemic lockdown has had a profound impact on physical and mental well-being throughout the world. Previous studies have revealed that complementary and alternative medicine (CAM) is frequently used for, and can be potential benefcial for strengthening physical mental resilience. The aims of this study were therefore to determine the prevalence and reasons for use of CAM ...

    • Safety in Avalanche Terrain: A mixed method study on how Norwegian backcountry skiers plan, conduct and evaluate trips 

      Stette Haarberg, Ingrid (Master thesis; Mastergradsoppgave, 2020-05-04)
      Every year backcountry skiers are victims of avalanches, and human errors are recognized as one of the most important factors in explaining why these accidents happen. We used an embedded mixed method design, in which the qualitative data was given priority, in order to investigate how backcountry skiers plan, conduct and evaluate trips in avalanche terrain. In all, a sample of 23 backcountry skiers ...

    • Safety of Complementary and Alternative Medicine (CAM) treatment among children and young adults who suffer from adverse effects of conventional cancer treatment: A systematic review 

      Mora, Dana Catalina; Kristoffersen, Agnete Egilsdatter; Overvåg, Grete; Jong, Miek; Mentink, Marit; Liu, Jianping; Stub, Trine (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-21)
      <p><b>Background:</b> Complementary and Alternative Medicine (CAM) is widely used around the world to treat adverse effects derived from cancer treatment among children and young adults. Parents often seek CAM to restore and maintain the child’s physical and emotional condition during and after cancer treatment. <p><b>Objectives:</b> The objectives of this review were (i) to identify ...

    • Safety of Treatment Provided by Homeopaths Homeopathic Aggravations, Adverse Effects and Risk Assessment 

      Stub, Trine (Doctoral thesis; Doktorgradsavhandling, 2014-03-28)
      Introduction Homeopathic treatment has a long tradition. Because of its widespread use as alternative therapy in Norway and Europe, but also in nations such as India, investigation into patient safety related to homeopathic treatment is important. Risk in homeopathy can be divided into direct and indirect risk. Direct risk is directly linked to the intervention itself while indirect risk is related ...

    • Salary and power: How occupational status affects children's occupational aspirations 

      Olsen, Marte; Parks-Stamm, Elizabeth J.; Thorsteinsen, Kjærsti; Martiny, Sarah E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-17)
      In many countries, labor markets are still highly gender segregated, with very few men working in communal occupations such as nursing. Because occupational aspirations start to develop during early childhood, it seems crucial to foster our understanding of which factors affect occupational aspirations during this period. Earlier correlational research showed that the status of occupations seems to ...

    • Saliva microbiota differs between children with low and high sedentary screen times 

      Engberg, Elina; Raju, Sajan; Figueiredo, Rejane A.O.; Weiderpass, Elisabete; Rounge, Trine Ballestad; Viljakainen, Heli (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-20)
      This study examined whether the diversity, composition and functional capacity of the saliva microbiota differed between children with low and high sedentary screen times. We analyzed the saliva microbiota using 16S rRNA (V3–V4) sequencing from 193 children with low and 183 children with high TV/screen viewing times while sitting. Microbiota diversity was higher among children with low screen ...

    • Salivary cortisol, perceived stress, and metabolic syndrome: a matched case-control study in female shift workers 

      Garcez, Anderson; Weiderpass, Elisabete; Canuto, Raquel; Lecke, Sheila Bünecker; Spritzer, Poli Mara; Pattussi, Marcos Pascoal; Olinto, Maria Teresa Anselmo (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-30)
      Objective: <br> Although the pathogenesis of metabolic syndrome (MetS) is complex and multifactorial, there is limited information if psychological factors, such as stress exposure, are involved in the etiology of MetS. Therefore, this study investigated the associations between MetS and cortisol levels and perceived stress levels among women shift workers in Southern Brazil.<br> Design: ...

    • Salivary glands in Svalbard reindeer (Rangifer tarandus platyrhynchus) and in Norwegian reindeer (Rangifer tarandus tarandus). 

      Rædergård, V.B.; Mathiesen, S.D.; Haga, Ø.E.; Vader, M.A.; Norberg, H.J.; Sørmo, W.; Tyler, N.J.C. (Journal article; Peer reviewed; Tidsskriftartikkel, 1999)

    • Salivary Oral Microbiome of Children With Juvenile Idiopathic Arthritis: A Norwegian Cross-Sectional Study 

      Frid, Paula; Baraniya, Divyashri; Halbig, Josefine Mareile; Rypdal, Veronika Gjertsen; Songstad, Nils Thomas; Rosén, Annika; Berstad, Johanna Elisabeth Rykke; Flatø, Berit; Alakwaa, Fadhl; Gil, Elisabeth Grut; Cetrelli, Lena Elisabet; Chen, Tsute; Al-hebshi, Nezar Noor; Nordal, Ellen Berit; Al-Haroni, Mohammed (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-04)
      <i>Background</i>: The oral microbiota has been connected to the pathogenesis of rheumatoid arthritis through activation of mucosal immunity. The objective of this study was to characterize the salivary oral microbiome associated with juvenile idiopathic arthritis (JIA), and correlate it with the disease activity including gingival inflammation.<p> <i>Methods</i>: Fifty-nine patients with JIA ...

    • Salmon louse infestation levels on sea trout can be predicted from a hydrodynamic lice dispersal model 

      Bøhn, Thomas; Nilsen, Rune; Gjelland, Karl Øystein; Biuw, Martin; Primicerio, Raul; Karlsen, Ørjan; Serra Llinares, Rosa Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-13)
      1. The abundance of the parasitic salmon louse has increased with the growth in aquaculture of salmonids in open net pens. This represents a threat to wild salmonid populations as well as a key limiting factor for salmon farming. The Norwegian ‘traffic light’ management system for salmon farming aims to increase aquaculture production while securing sustainable wild salmonid populations. However, ...

    • Salmonella diarizonae hos dyr i Norge. Konsekvenser for dyr og mennesker. 

      Nesbakken, Truls; Lassen, Jørgen Fr; Nygård, Karin Maria; Østerås, Olav; Høiby, Ernst Arne; Kapperud, Georg; Lunestad, Bjørn Tore; Olsvik, Ørjan; Robertson, Lucy; Tranulis, Michael A.; Tryland, Morten; Rimstad, Espen (Research report; Forskningsrapport, 2008-09-09)
      S. diarizonae er et subspecies av Salmonella som påvises endemisk hos sau i enkelte regioner i Norge. Det er derfor stilt spørsmål om mikrobens potensielle og reelle betydning for både folke- og dyrehelsen. Det er også stilt spørsmål ved påstanden om at Norge har en tilnærmet salmonella-fri husdyrpopulasjon kan forsvares når S. diarizonae påvises relativt ofte hos sau i Norge i dag. Mattilsynet har ...

    • Samarbeid for å fremme seksuell helse i ungdomsskolen: En kvalitativ undersøkelse av helsesykepleiernes erfaringer med undervisning i seksuell helse og tverrfaglig samarbeid med lærer om seksualitetsundervisningen 

      Flatsetø, Henriette (Mastergradsoppgave; Master thesis, 2022-10-18)
      Bakgrunn: Formålet med denne studien var å finne ut hvordan helsesykepleiere erfarer å undervise i seksuell helse i ungdomsskolen, og hvordan de erfarer tverrfaglig samarbeid med lærer om undervisningen. Problemstilling: Hvordan erfarer helsesykepleiere å undervise i seksuell helse, og hva er deres erfaringer med tverrfaglig samarbeid om undervisning i seksuell helse i ungdomsskolen? Teori: ...

    • Samarbeid mellom operasjonssykepleiere og anestesisykepleiere for å forebygge leiringskomplikasjoner: En litteraturstudie med eksempler fra litotomileie. 

      Skaalvik, Gurå (Master thesis; Mastergradsoppgave, 2018-05-04)
      Hensikt: Å få svar på hvilke forutsetninger for samarbeid mellom operasjonssykepleiere og anestesisykepleiere som behøves for å forhindre leiringskomplikasjoner, med eksempler fra litotomileie. Metode: Det er gjort en litteraturstudie, 14 artikler og masteroppgaver er blitt inkludert. En tematisk analyse er blitt utført. Funn: Følgende temaer kom frem; Individuell sykepleie og omsorg for pasienten, ...