Blar i forfatter Det helsevitenskapelige fakultet "Croteau-Chonka, DC"

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    • Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits 

      Randall, JC; Winkler, TW; Kutalik, Z; Berndt, SI; Jackson, AU; Monda, KL; Kilpelainen, TO; Esko, T; Magi, R; Li, SX; Workalemahu, T; Feitosa, MF; Croteau-Chonka, DC; Day, FR; Fall, T; Ferreira, T; Gustafsson, S; Locke, AE; Mathieson, I; Scherag, A; Vedantam, S; Wood, AR; Liang, LM; Steinthorsdottir, V; Thorleifsson, G; Dermitzakis, ET; Dimas, AS; Karpe, F; Min, JL; Nicholson, G; Clegg, DJ; Person, T; Krohn, JP; Bauer, S; Buechler, C; Eisinger, K; Bonnefond, A; Froguel, P; Hottenga, JJ; Prokopenko, I; Waite, LL; Harris, TB; Smith, AV; Shuldiner, AR; McArdle, WL; Caulfield, MJ; Munroe, PB; Gronberg, H; Chen, YDI; Li, G; Beckmann, JS; Johnson, T; Thorsteinsdottir, U; Teder-Laving, M; Khaw, KT; Wareham, NJ; Zhao, JH; Amin, N; Oostra, BA; Kraja, AT; Province, MA; Cupples, LA; Heard-Costa, NL; Kaprio, J; Ripatti, S; Surakka, I; Collins, FS; Saramies, J; Tuomilehto, J; Jula, A; Salomaa, V; Erdmann, J; Hengstenberg, C; Loley, C; Schunkert, H; Lamina, C; Wichmann, HE; Albrecht, E; Gieger, C; Hicks, AA; Johansson, A; Pramstaller, PP; Kathiresan, S; Speliotes, EK; Penninx, B; Hartikainen, AL; Jarvelin, MR; Gyllensten, U; Boomsma, DI; Campbell, H; Wilson, JF; Chanock, SJ; Farrall, M; Goel, A; Medina-Gomez, C; Rivadeneira, F; Estrada, K; Uitterlinden, AG; Hofman, A; Zillikens, MC; den Heijer, M; Kiemeney, LA; Maschio, A; Hall, P; Tyrer, J; Teumer, A; Volzke, H; Kovacs, P; Tonjes, A; Mangino, M; Spector, TD; Hayward, C; Rudan, I; Hall, AS; Samani, NJ; Attwood, AP; Sambrook, JG; Hung, J; Palmer, LJ; Lokki, ML; Sinisalo, J; Boucher, G; Huikuri, H; Lorentzon, M; Ohlsson, C; Eklund, N; Eriksson, JG; Barlassina, C; Rivolta, C; Nolte, IM; Snieder, H; Van der Klauw, MM; Van Vliet-Ostaptchouk, JV; Gejman, PV; Shi, JX; Jacobs, KB; Wang, ZM; Bakker, SJL; Leach, IM; Navis, G; van der Harst, P; Martin, NG; Medland, SE; Montgomery, GW; Yang, J; Chasman, DI; Ridker, PM; Rose, LM; Lehtimaki, T; Raitakari, O; Absher, D; Iribarren, C; Basart, H; Hovingh, KG; Hypponen, E; Power, C; Anderson, D; Beilby, JP; Hui, JN; Jolley, J; Sager, H; Bornstein, SR; Schwarz, PEH; Kristiansson, K; Perola, M; Lindstrom, J; Swift, AJ; Uusitupa, M; Atalay, M; Lakka, TA; Rauramaa, R; Bolton, JL; Fowkes, G; Fraser, RM; Price, JF; Fischer, K; KrjutAikov, K; Metspalu, A; Mihailov, E; Langenberg, C; Luan, JA; Ong, KK; Chines, PS; Keinanen-Kiukaanniemi, SM; Saaristo, TE; Edkins, S; Franks, PW; Hallmans, G; Shungin, D; Morris, AD; Palmer, CNA; Erbel, R; Moebus, S; Nothen, MM; Pechlivanis, S; Hveem, Kristian; Narisu, N; Hamsten, A; Humphries, SE; Strawbridge, RJ; Tremoli, E; Grallert, H; Thorand, B; Illig, T; Koenig, W; Muller-Nurasyid, M; Peters, A; Boehm, BO; Kleber, ME; Marz, W; Winkelmann, BR; Kuusisto, J; Laakso, M; Arveiler, D; Cesana, G; Kuulasmaa, K; Virtamo, J; Yarnell, JWG; Kuh, D; Wong, A; Lind, L; de Faire, U; Gigante, B; Magnusson, PKE; Pedersen, NL; Dedoussis, G; Dimitriou, M; Kolovou, G; Kanoni, S; Stirrups, K; Bonnycastle, LL; Njølstad, Inger; Wilsgaard, Tom; Ganna, A; Rehnberg, E; Hingorani, A; Kivimaki, M; Kumari, M; Assimes, TL; Barroso, IS; Boehnke, M; Borecki, IB; Deloukas, P; Fox, CS; Frayling, T; Groop, LC; Haritunians, T; Hunter, D; Ingelsson, E; Kaplan, R; Mohlke, KL; O'Connell, JR; Schlessinger, D; Strachan, DP; Stefansson, K; van Duijn, CM; Abecasis, GR; McCarthy, MI; Hirschhorn, JN; Qi, L; Loos, Ruth J.F.; Lindgren, CM; North, KE; Heid, IM (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Given the anthropometric differences between men and women and previous evidence of sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic associations with height, weight, body mass index, waist circumference, hip circumference, and waist-to-hip-ratio (133,723 individuals) and took forward 348 SNPs into follow-up (additional 137,052 individuals) in a total ...

    • Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained 

      Wu, Y; Waite, LL; Jackson, Anne U.; Sheu, WHH; Buyske, Steven; Absher, D; Arnett, DK; Boerwinkle, E; Bonnycastle, LL; Carty, CL; Cheng, I; Cochran, B; Croteau-Chonka, DC; Dumitrescu, L; Eaton, CB; Franceschini, N; Guo, XQ; Henderson, BE; Hindorff, LA; Kim, E; Kinnunen, L; Komulainen, P; Lee, WJ; Le Marchand, L; Lin, Y; Lindstrom, J; Holmen, Oddgeir; Mitchell, SL; Narisu, N; Robinson, JG; Schumacher, F; Stancaakovaa, A; Sundvall, J; Sung, YJ; Swift, AJ; Wang, WC; Wilkens, L; Wilsgaard, Tom; Young, AM; Adair, LS; Ballantyne, CM; Buzkova, P; Chakravarti, A; Collins, FS; Duggan, D; Feranil, AB; Ho, LT; Hung, YJ; Hunt, SC; Hveem, Kristian; Juang, JMJ; Kesaniemi, AY; Kuusisto, J; Laakso, M; Lakka, TA; Lee, IT; Leppert, MF; Matise, TC; Moilanen, L; Njølstad, Inger; Peters, U; Quertermous, T; Rauramaa, R; Rotter, JI; Saramies, J; Tuomilehto, J; Uusitupa, M; Wang, TD; Boehnke, M; Haiman, CA; Chen, YDI; Kooperberg, C; Assimes, TL; Crawford, DC; Hsiung, CA; North, KE; Mohlke, Karen L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Genome-wide association studies (GWAS) have identified ~ 100 loci associated with blood lipid levels, but much of the trait heritability remains unexplained, and at most loci the identities of the trait-influencing variants remain unknown. We conducted a trans-ethnic fine-mapping study at 18, 22, and 18 GWAS loci on the Metabochip for their association with triglycerides (TG), high-density ...