Blar i forfatter Det helsevitenskapelige fakultet "Dahl, Jesper"

Viser treff 1-4 av 4

    • A combined effect of anti-HPA-1a and anti-HLA Class I in pregnancy? 

      Dahl, Jesper; Skogen, Bjørn; Kjær, Mette; Husebekk, Anne; Kjeldsen-Kragh, Jens; Tiller, Heidi (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-30)
      <i>Background</i> - Maternal anti–human leukocyte antigen (HLA) Class I is commonly detected alongside anti–human platelet antigen (HPA)-1a in fetal and neonatal alloimmune thrombocytopenia (FNAIT). Little is known regarding whether the presence of anti-HLA Class I may exert an additive effect on the risk and severity of FNAIT.<br><br> <i>Methods and Materials</i> - We reanalyzed samples originally ...

    • Individual Variation in Adaptive Immune Responses and Risk of Hip Fracture-A NOREPOS Population-Based Cohort Study 

      Dahl, Jesper; Holvik, Kristin; Heldal, Einar; Grimnes, Guri; Hoff, Mari; Finnes, Trine; Apalset, Ellen Margrete; Meyer, Haakon E (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-22)
      Immune‐mediated bone loss significantly impacts fracture risk in patients with autoimmune disease, but to what extent individual variations in immune responses affect fracture risk on a population level is unknown. To examine how immune responses relate to risk of hip fracture, we looked at the individual variation in a post‐vaccination skin test response that involves some of the immune pathways ...

    • Maternal and neonatal characteristics of pregnancies with detected thrombocytopenia and anti-HLA class I antibodies 

      Dahl, Jesper (Master thesis; Mastergradsoppgave, 2012-06-01)
      Introduction: Anti-HPA 1a antibodies in connection with HPA 1a alloimmunized pregnancies have been shown to be associated with a lower birth weight in boys. The proposed mechanism for this was an affected placentation through binding of antibodies to the β3 integrin on vascular endothelial cells and/or invading throphoblasts. It was also hypothesized that thrombocytopenia could have affected placental ...

    • Maternal Anti-HLA Class I Antibodies in Connection with Pregnancy and Neonatal Thrombocytopenia – a Cause for Concern? Clinical Characteristics and Antibody Analysis of Retrospective and Prospective Populations 

      Dahl, Jesper (Doctoral thesis; Doktorgradsavhandling, 2017-09-08)
      Background: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is caused by maternal antibodies that target fetal platelets during pregnancy. It can occur when fetal platelets express a paternally-inherited antigen that is not shared by the mother. Maternal antibodies that cause FNAIT are directed against human platelet antigens (HPAs) on fetal platelets, and the resulting fetal/ neonatal ...