Blar i forfatter Det helsevitenskapelige fakultet "Dumitriu, Gianina Aurica"
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Serine residue 115 of MAPK-activated protein kinase MK5 is crucial for its PKA-regulated nuclear export and biological function.
Kostenko, Sergiy Viktorovich; Shiryaev, Alexey; Gerits, Nancy; Dumitriu, Gianina Aurica; Klenow, Helle Bagterp; Johannessen, Mona; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2010) -
A study of the protein kinase MK5's effect on melanoma cell proliferation
Dumitriu, Gianina Aurica (Master thesis; Mastergradsoppgave, 2012-09-14)The mitogen-activated protein kinases (MAPKs) play a crucial role in cellular processes such as proliferation, differentiation, apoptosis, metabolism and motility. Both conventional and atypical MAPKs can phosphorylate other proteins referred to as MAPK- activated protein kinases (MAPKAPK) such as MK5 or p38-regulated /activated protein kinase. Mutations in the MK5 gene have been detected in lung, ...