Blar i forfatter Det helsevitenskapelige fakultet "Dybwik, Knut"

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    • Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis 

      Skjeflo, Espen Waage; Sagatun, Caroline; Dybwik, Knut; Aam, Sturla; Urving, Sven Haakon; Nunn, Miles A.; Fure, Hilde; Lau, Corinna; Brekke, Ole Lars; Huber-Lang, Markus; Barratt-Due, Andreas; Nielsen, Erik Waage; Mollnes, Tom Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-27)
      Introduction: Sepsis is an exaggerated and dysfunctional immune response to infection. Activation of innate immunity recognition systems including complement and the Toll-like receptor family initiate this disproportionate inflammatory response. The aim of this study was to explore the effect of combined inhibition of the complement component C5 and the Toll-like receptor co-factor CD14 on survival, ...

    • Ethical challenges in home mechanical ventilation : a secondary analysis 

      Dybwik, Knut; Nielsen, Erik Waage; Brinchmann, Berit Støre (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The aim of this study was to explore the ethical challenges in home mechanical ventilation based on a secondary analysis of qualitative empirical data. The data included perceptions of healthcare professionals in hospitals and community health services and family members of children and adults using home mechanical ventilation. The findings show that a number of ethical challenges, or dilemmas, ...

    • "Fighting the system" : families caring for ventilator-dependent children and adults with complex health care needs at home 

      Dybwik, Knut; Tollåli, Terje; Nielsen, Erik Waage; Brinchmann, Berit Støre (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      An increasing number of individuals with complex health care needs now receive life-long and lifeprolonging ventilatory support at home. Family members often take on the role of primary caregivers. The aim of this study was to explore the experiences of families giving advanced care to family members dependent on home mechanical ventilation. Using qualitative research methods, a Grounded Theory ...

    • Gas embolism during surgery. A complement mediated condition? 

      Storm, Benjamin Stage; Christiansen, Dorte; Dybwik, Knut; Mollnes, Tom Eirik; Nielsen, Erik Waage (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-01)
      <p><i>Introduction</i>: Venous air embolism (VAE) may arise during surgical procedures. VAE might be complicated with a systemic inflammatory response, disseminated intervascular coagulation, multi-organ failure and cardiovascular collapse. During a short time-span, three patients at our institution developed signs of VAE in conjunction with gynecological surgery. One died, one developed severe ...

    • Hjemmerespiratorbehandling "Mellom barken og veden" En kvalitativ studie av intensivbehandling i hjemmet 

      Dybwik, Knut (Doctoral thesis; Doktorgradsavhandling, 2011-10-28)
      Helsepersonell i sykehus, familiemedlemmer og helsepersonell i kommunehelsetjenesten er kritisk viktige for gjennomføringen av hjemmerespiratorbehandling, både i sykehus og i pasientens hjem. Derfor studerte vi deres erfaringer. Vi gjennomførte 11 fokusgrupper og 10 dybdeintervju. Vi fant at ulik fordeling av entusiastiske leger og sykepleiere mellom norske sykehus var hovedårsaken til de store ...

    • Home mechanical ventilation and specialised health care in the community : between a rock and a hard place 

      Dybwik, Knut; Nielsen, Erik Waage; Brinchmann, Berit Støre (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Home mechanical ventilation probably represents the most advanced and complicated type of medical treatment provisioned outside a hospital setting. The aim of this study was both to explore the challenges experienced by health care professionals in community health care services when caring for patients dependent on home mechanical ventilation, continual care and highly advanced technology, and their ...

    • Why does the provision of home mechanical ventilation vary so widely? 

      Dybwik, Knut; Tollåli, Terje; Nielsen, Erik Waage; Brinchmann, Berit Støre (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      There is wide variation in the provision of home mechanical ventilation (HMV) throughout Europe, but the provision of home mechanical ventilation can also vary within countries. In 2008, the overall prevalence of HMV in Norway was 19.9/100,000, and there were huge regional differences in treatment prevalence. The aim of this study is to find explanations for these differences. We gathered ...