Blar i forfatter Det helsevitenskapelige fakultet "Francis, Nick A."

Viser treff 1-2 av 2

    • Clinical Features and C-Reactive Protein as Predictors of Bacterial Exacerbations of COPD. 

      Francis, Nick A.; Gillespie, David; Wootton, M.; White, Patrick; Bates, Janine; Richards, J.; Melbye, Hasse; Hood, Kerenza; Butler, Christopher C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-01)
      Introduction: Identifying predictors of bacterial and viral pathogens in sputum from patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) may help direct management.<p> <p>Methods: We used data from a trial evaluating a C-reactive protein (CRP) point of care guided approach to managing COPD exacerbations in primary care. We used regression analyses to identify ...

    • General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE study): Study protocol for a randomised controlled trial 

      Bates, Janine; Francis, Nick A.; White, Patrick; Gillespie, David; Thomas-Jones, Emma; Breen, Rachel; Kirby, Nigel; Hood, Kerry; Gal, Micaela; Phillips, Rhiannon; Naik, Gurudutt; Cals, Jochen; Llor, Carl; Melbye, Hasse; Wootton, Mandy; Riga, Evgenia; Cochrane, Ann; Howe, Robin; Fitzsimmons, Deborah; Sewell, Bernadette; Alam, Mohammed Fasihul; Butler, Christopher C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-29)
      Background: <br>Most patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed an antibiotic, which may not always be appropriate and may cause harm. C-reactive protein (CRP) is an acute-phase biomarker that can be rapidly measured at the point of care and may predict benefit from antibiotic treatment in AECOPD. It is not clear ...