• Homology modeling to screen for potential binding of contaminants to thyroid hormone receptor and transthyretin in glaucous gull (Larus hyperboreus) and herring gull (Larus argentatus) 

      Mortensen, Åse-Karen; Mæhre, Silje; Kristiansen, kurt; Heimstad, Eldbjørg Sofie; Gabrielsen, Geir W.; Jenssen, Bjørn Munro; Sylte, Ingebrigt (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-11)
      Thyroid hormone disrupting chemicals (THDCs) are of major concern in ecotoxicology. With the increased number of emerging chemicals on the market there is a need to screen for potential THDCs in a cost-efficient way, and <i>in silico</i> modeling is an alternative to address this issue. In this study homology modeling and docking was used to screen a list of 626 compounds for potential thyroid hormone ...
    • Magnetic resonance imaging for non-invasive measurement of plastic ingestion in marine wildlife 

      Anderssen, Kathryn Elizabeth; Gabrielsen, Geir W.; Kranz, Mathias; Collard, France (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)
      Monitoring plastic ingestion by marine wildlife is important for both characterizing the extent of plastic pollution in the environment and understanding its effect on species and ecosystems. Current methods to detect plastic in the digestive system of animals are slow and invasive, such that the number of animals that can be screened is limited. In this article, magnetic resonance imaging (MRI) ...
    • Targeted PFAS analyses and Extractable Organofluorine – Enhancing our Understanding of the presence of unknown PFAS in Norwegian wildlife 

      Herzke, Dorte; Nikiforov, Vladimir; Yeung, Leo WY.; Moe, Børge; Routti, Heli Anna Irmeli; Nygård, Torgeir; Gabrielsen, Geir W.; Hanssen, Linda (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)
      With the current possible presence of thousands of PFAS compounds in industrial emissions, there is an increasing need to assess the impacts of PFAS regulation of conventional PFAS on one hand and the exposure to emerging and yet unknown PFAS on the other. Today’s analytical methodologies using targeted approaches are not sufficient to determine the complete suite of PFAS present. To evaluate the ...