Now showing items 1-3 of 3

    • Non-skeletal health effects of Vitamin D supplementation: A systematic review on findings from meta-Analyses summarizing trial data 

      Rejnmark, Lars; Bislev, Lise Sofie; Cashman, Kevin D.; Eiríksdóttir, Gudny; Gaksch, Martin; Grübler, Martin; Grimnes, Guri; Gudnason, Vilmundur; Lips, Paul; Pilz, Stefan; Van Schoor, Natasja M.; Kiely, Mairead; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-07)
      Background:<br>A large number of observational studies have reported harmful effects of low 25-hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic quantitative review on characteristics of randomized clinical trials (RCTs) included in meta-analyses (MAs) on non-skeletal effects of vitamin D supplementation.<br>Methods and findings:<br>We identified systematic reviews ...
    • Rationale and plan for vitamin D food fortification: A review and guidance paper 

      Pilz, Stefan; März, Winfried; Cashman, Kevin D; Kiely, Mairead; Whiting, Susan J; Holick, Michael F.; Grant, William B; Pludowski, Pawel; Hiligsmann, Mickaël; Trummer, Christian; Schwetz, Verena; Lerchbaum, Elisabeth; Pandis, Marlene; Tomaschitz, Andreas; Grübler, Martin; Gaksch, Martin; Verheyen, Nicolas; Hollis, Bruce W; Rejnmark, Lars; Karras, Spyridon N.; Hahn, Andreas; Bischoff-Ferrari, Heike Annette; Reichrath, Jörg; Jorde, Rolf; Elmadfa, Ibrahim; Vieth, Reinhold; Scragg, Robert; Calvo, Mona S; Van Schoor, Natasja M; Bouillon, Roger; Lips, Paul; Itkonen, Suvi T; Martineau, Adrian R; Lamberg-Allardt, Christel; Zittermann, Armin (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-17)
      Vitamin D deficiency can lead to musculoskeletal diseases such as rickets and osteomalacia, but vitamin D supplementation may also prevent extraskeletal diseases such as respiratory tract infections, asthma exacerbations, pregnancy complications and premature deaths. Vitamin D has a unique metabolism as it is mainly obtained through synthesis in the skin under the influence of sunlight (i.e., ...
    • Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium 

      Gaksch, Martin; Jorde, Rolf; Grimnes, Guri; Joakimsen, Ragnar Martin; Schirmer, Henrik; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Njølstad, Inger; Løchen, Maja-Lisa; März, Winfried; Kleber, Marcus E.; Tomaschitz, Andreas; Grübler, Martin; Eiriksdottir, Gudny; Gudmundsson, Elias F.; Harris, Tamara B.; Cotch, Mary Frances; Aspelund, Thor; Gudnason, Vilmundur; Rutters, Femke; Beulens, Joline W.J.; Van't Riet, Esther; Nijpels, Giel; Dekker, Jacqueline M.; Grove-Laugesen, Diana; Rejnmark, Lars; Busch, Markus A.; Mensink, Gert B.M.; Scheidt-Nave, Christa; Thamm, Michael; Swart, Karin M.A.; Brouwer, Ingeborg A.; Lips, Paul; Van Schoor, Natasja M.; Sempos, Christopher T.; Durazo-Arvizu, Ramón A.; Škrabáková, Zuzana; Dowling, Kirsten G.; Cashman, Kevin D.; Kiely, Mairead; Pilz, Stefan (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-16)
      Background:<br>Vitamin D deficiency may be a risk factor for mortality but previous meta-analyses lacked standardization of laboratory methods for 25-hydroxyvitamin D (25[OH]D) concentrations and used aggregate data instead of individual participant data (IPD). We therefore performed an IPD meta-analysis on the association between standardized serum 25(OH)D and mortality.<br>Methods:<br>In a European ...