Blar i forfatter Det helsevitenskapelige fakultet "Naik, Gurudutt"

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    • Associations with antibiotic prescribing for acute exacerbation of COPD in primary care: Secondary analysis of a randomised controlled trial 

      Gillespie, David; Butler, Christopher C.; Bates, Janine; Hood, Kerenza; Melbye, Hasse; Phillips, Rhiannon; Stanton, Helen; Alam, Mohammed Fasihul; Cals, Jochen; Cochrane, Ann; Kirby, Nigel; Llor, Carl; Lowe, Rachel; Naik, Gurudutt; Riga, Evgenia; Sewell, Bernadette; Thomas-Jones, Emma; White, Patrick; Francis, Nick (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-26)
      <i>Background</i> - C-reactive protein (CRP) point-of-care testing can reduce antibiotic use in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in primary care, without compromising patient care. Further safe reductions may be possible.<br><br> <i>Aim</i> - To investigate the associations between presenting features and antibiotic prescribing in patients with ...

    • Associations with Post-Consultation Health-Status in Primary Care Managed Acute Exacerbation of COPD 

      Gillespie, David; Francis, Nick; Ahmed, Haroon; Hood, Kerenza; Llor, Carl; White, Patrick; Thomas-Jones, Emma; Stanton, Helen; Sewell, Bernadette; Phillips, Rhiannon; Naik, Gurudutt; Melbye, Hasse; Lowe, Rachel; Kirby, Nigel; Cochrane, Ann; Bates, Janine; Alam, Mohammed Fasihul; Butler, Christopher (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-16)
      Background: It has been demonstrated that antibiotic prescribing for Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) can be safely reduced in primary care when general practitioners have access to C-reactive protein (CRP) rapid testing.<p> <p>Aim: To investigate the factors associated with post-consultation COPD health status in patients presenting with AECOPD in this sett ...

    • C-reactive protein point-of-care testing for safely reducing antibiotics for acute exacerbations of chronic obstructive pulmonary disease: The PACE RCT 

      Francis, Nick; Gillespie, David; White, Patrick; Bates, Janine; Lowe, Rachel; Sewell, Bernadette; Phillips, Rhiannon; Stanton, Helen; Kirby, Nigel; Wootton, Mandy; Thomas-Jones, Emma; Hood, Kerenza; Llor, Carl; Cals, Jochen; Melbye, Hasse; Naik, Gurudutt; Gal, Micaela; Fitzsimmons, DF; Alam, Mohammed Fasihul; Riga, Evgenia; Cochrane, Ann; Butler, Christopher C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03)
      Background - Most patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed antibiotics, but these may not be beneficial, and they can cause side effects and increase the risk of subsequent resistant infections. Point-of-care tests (POCTs) could safely reduce inappropriate antibiotic prescribing and antimicrobial resistance.<p> ...

    • C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations 

      Butler, Christopher C; Gillespie, David; White, Patrick; Bates, Janine; lowe, rachel; Thomas-Jones, Emma; Wootton, Mandy; Hood, Kerenza; Phillips, Rhiannon; Melbye, Hasse; Llor, Carl; Cals, Jochen W L; Naik, Gurudutt; Kirby, Nigel; Gal, Micaela; Riga, Evgenia; Francis, Nick A (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-11)
      <i>BACKGROUND</i> - Point-of-care testing of C-reactive protein (CRP) may be a way to reduce unnecessary use of antibiotics without harming patients who have acute exacerbations of chronic obstructive pulmonary disease (COPD).<p><p> <i>METHODS</i> - We performed a multicenter, open-label, randomized, controlled trial involving patients with a diagnosis of COPD in their primary care clinical ...

    • General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE study): Study protocol for a randomised controlled trial 

      Bates, Janine; Francis, Nick A.; White, Patrick; Gillespie, David; Thomas-Jones, Emma; Breen, Rachel; Kirby, Nigel; Hood, Kerry; Gal, Micaela; Phillips, Rhiannon; Naik, Gurudutt; Cals, Jochen; Llor, Carl; Melbye, Hasse; Wootton, Mandy; Riga, Evgenia; Cochrane, Ann; Howe, Robin; Fitzsimmons, Deborah; Sewell, Bernadette; Alam, Mohammed Fasihul; Butler, Christopher C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-29)
      Background: <br>Most patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed an antibiotic, which may not always be appropriate and may cause harm. C-reactive protein (CRP) is an acute-phase biomarker that can be rapidly measured at the point of care and may predict benefit from antibiotic treatment in AECOPD. It is not clear ...