• Accuracy of neuropathic pain measurements in patients with symptoms of polyneuropathy: validation of painDETECT, Self-Completed Leeds Assessment of Neuropathic Symptoms and Signs, and Douleur Neuropathique 4 

      Dunker, Øystein; Grotle, Margreth; Kvaløy, Marie Bu; Uglem, Martin; Løseth, Sissel; Hjelland, Ina Elen; Kleggetveit, Inge Petter; Allen, Sara Maria; Vigeland, Maria Dehli; Killingmo, Rikke Munk; Sand, Trond; Nilsen, Kristian Bernhard (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-10)
      Pain is a common symptom in patients referred to polyneuropathy assessment. Diagnostic evaluation and choice of treatment may depend on whether the pain is likely to be neuropathic or not. This study aimed to investigate the diagnostic accuracy of 3 tools commonly used to differentiate between neuropathic and nonneuropathic pain. To accomplish this, we included patients with bilateral distal lower ...
    • A bidirectional study of the association between insomnia, high-sensitivity C-reactive protein, and comorbid low back pain and lower limb pain 

      Ho, Kevin Kwan Ngai; Skarpsno, Eivind S.; Nilsen, Kristian Bernhard; Ferreira, Paulo Herrique; Pinheiro, Marina; Hopstock, Laila Arnesdatter; Johnsen, Marianne Bakke; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Stubhaug, Audun; Simic, Milena (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-14)
      Objectives - To examine the possible bidirectional association between insomnia and comorbid chronic low back pain (LBP) and lower limb pain and to explore whether high-sensitivity C-reactive protein (hsCRP) amplifies these associations.<p> <p>Methods - We calculated adjusted risk ratios (RR) with 95% confidence intervals (CI) for the development of insomnia and mild-to-severe chronic LBP and ...
    • Does insomnia modify the association between C-reactive protein and migraine? The Tromsø Study 2015-2016. 

      Hagen, Knut; Hopstock, Laila Arnesdatter; Eggen, Anne Elise; Mathiesen, Ellisiv B.; Nilsen, Kristian Bernhard (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-12)
      <p><i>Background - </i>The relationship between high sensitivity C-reactive protein and migraine is unclear. The aim of this cross-sectional population-based study was to investigate the association between high sensitivity C-reactive protein and types of headache, and to evaluate the impact of insomnia on this association. <p><i>Methods - </i>A total of 20,486 (63%) out of 32,591 invited, aged ≥40 ...
    • Shift work, low-grade inflammation, and chronic pain: a 7-year prospective study 

      Christensen, Jan Olav; Nilsen, Kristian Bernhard; Hopstock, Laila Arnesdatter; Steingrimsdottir, Olöf Anna; Nielsen, Christopher Sivert; Zwart, John-Anker; Matre, Dagfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-07)
      <i>Objectives</i> - We investigated prospective associations of shift work with chronic pain and C‐reactive protein (CRP), an indicator of inflammation. Furthermore, we elucidated CRP as a possible mediator and/or moderator of effects of shift work on pain.<br><br> <i>Methods</i> - Data from a 7 years follow‐up study were analyzed (<i>N</i> = 2323). Shift work and chronic pain of “neck/shoulder”, ...
    • Sleep patterns and insomnia in a large population-based study of middle-aged and older adults: The Tromsø study 2015–2016 

      Sivertsen, Børge; Pallesen, Ståle; Friborg, Oddgeir; Nilsen, Kristian Bernhard; Bakke, Øystein; Goll, Jonas Bjørnskov; Hopstock, Laila Arnesdatter (Journal article; Tidsskriftartikkel, 2020-05-29)
      Epidemiological studies assessing adult sleep duration have yielded inconsistent findings and there are still large variations in estimation of insomnia prevalence according to the most recent diagnostic criteria. Our objective was to describe sleep patterns in a large population of middle‐aged and older adults, by employing accurate measures of both sleep duration and insomnia. Data stem from the ...