• The impact of partial hepatectomy on oxidative state in the liver remnant - An in vivo swine model 

      Florholmen-Kjær, Åse; Goll, Rasmus; Fuskevåg, Ole-Martin; Nygård, Ingvild; Paulssen, Ruth H; Revhaug, Arthur; Mortensen, Kim Erlend (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-24)
      Background Previous studies on oxidative state after partial hepatectomy (PHx) report conflicting data on levels of glutathione (GSH) and are mainly presented in rodent models by methodology less sensitive than the present technologies. The current swine model presents GSH levels and the following genetic response post-PHx, utilizing an analytical platform more sensitive and precise than earlier ...
    • Increased sinusoidal flow is not the primary stimulus to liver regeneration 

      Conley, LN; Mortensen, Kim Erlend; Nygård, Ingvild; Sørensen, Peter; Mortensen, Elin; Bendixen, C; Revhaug, Arthur (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
    • Tissue remodelling following resection of porcine liver 

      Nygård, Ingvild; Mortensen, Kim Erlend; Hedegaard, Jakob; Conley, Lene Nagstrup; Bendixen, Christian; Sveinbjørnsson, Baldur; Revhaug, Arthur (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-06)
      Aim. To study genes regulating the extracellular matrix (ECM) and investigate the tissue remodelling following liver resection in porcine. <p>Methods. Four pigs with 60% partial hepatectomy- (PHx-) induced liver regeneration were studied over six weeks. Four pigs underwent sham surgery and another four pigs were used as controls of the normal liver growth. Liver biopsies were taken upon laparotomy, ...