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    • Novel GTF2I-PDGFRB and IKZF1-TYW1 fusions in pediatric leukemia with normal karyotype 

      Panagopoulos, Ioannis; Brunetti, Marta; Stoltenberg, Margrethe; Strandabø, Rønnaug; Staurseth, Julie; Andersen, Kristin; Kostolomov, Ilya; Hveem, Tarjei Sveinsgjerd; Lorenz, Susanne; Nystad, Tove Anita; Flægstad, Trond; Micci, Francesca; Heim, Sverre (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-29)
      <i>Background</i> - Many cases of acute lymphoblastic leukemia (ALL) carry visible acquired chromosomal changes of pathogenetic, diagnostic, and prognostic importance. Nevertheless, from one-fourth to half of newly diagnosed ALL patients have no visible chromosomal changes detectable by G-banding analysis at diagnosis. The introduction of powerful molecular methodologies has shown that many ...