• Effect of major lifestyle risk factors, independent and jointly, on life expectancy with and without cardiovascular disease: results from the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES) 

      O'Doherty, Mark G.; Cairns, Karen; O'Neill, Vikki; Lamrock, Felicity; Jørgensen, Torben; Brenner, Hermann; Schöttker, Ben; Wilsgaard, Tom; Siganos, Galatios; Kuulasmaa, Kari; Boffetta, Paolo; Trichopoulou, Antonia; Kee, Frank (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-18)
      Seldom have studies taken account of changes in lifestyle habits in the elderly, or investigated their impact on disease-free life expectancy (LE) and LE with cardiovascular disease (CVD). Using data on subjects aged 50+ years from three European cohorts (RCPH, ESTHER and Tromsø), we used multi-state Markov models to calculate the independent and joint effects of smoking, physical activity, obesity ...
    • Quantification of the smoking-associated cancer risk with rate advancement periods: Meta-analysis of individual participant data from cohorts of the CHANCES consortium 

      Ordóñez-Mena, José Manuel; Schöttker, Ben; Mons, Ute; Jenab, Mazda; Freisling, Heinz; Bueno-De-Mesquita, Hendrik Bastiaan; O'Doherty, Mark G.; Scott, Angela; Kee, Frank; Stricker, Bruno H.; Hofman, Albert; de Keyser, Catherine E.; Ruiter, Rikje; Söderberg, Stefan; Jousilahti, Pekka; Kuulasmaa, Kari; Freedman, Neal D.; Wilsgaard, Tom; de Groot, Lisette C.P.G.M.; Kampman, Ellen; Håkansson, Niclas; Orsini, Nicola; Wolk, Alicja; Nilsson, Lena Maria; Tjønneland, Anne; Pająk, Andrzej; Malyutina, Sofia; Kúbinová, Růžena; Tamosiunas, Abdonas; Bobak, Martin; Katsoulis, Michail; Orfanos, Philippos; Boffetta, Paolo; Trichopoulou, Antonia; Brenner, Hermann (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-05)
      Background:<br> Smoking is the most important individual risk factor for many cancer sites but its association with breast and prostate cancer is not entirely clear. Rate advancement periods (RAPs) may enhance communication of smoking related risk to the general population. Thus, we estimated RAPs for the association of smoking exposure (smoking status, time since smoking cessation, smoking ...