Browsing Det helsevitenskapelige fakultet by Author "Page, Christian"

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    • Genome-wide DNA methylation in saliva and body size of adolescent girls 

      Rounge, Trine Ballestad; Page, Christian; Lepistö, Maija; Ellonen, Pekka; Andreassen, Bettina K; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-20)
      Aim:<br>We performed an epigenome-wide association study within the Finnish Health in Teens cohort to identify differential DNA methylation and its association with BMI in adolescents.<br>Materials & methods:<br>Differential DNA methylation analyses of 3.1 million CpG sites were performed in saliva samples from 50 lean and 50 heavy adolescent girls by genome-wide targeted bisulfite-sequencing.<br> ...

    • Lifetime ultraviolet radiation exposure and DNA methylation in blood leukocytes: The Norwegian Women and Cancer Study 

      Page, Christian; Djordjilovic, Vera; Nøst, Therese Haugdahl; Ghiasvand, Reza; Sandanger, Torkjel M; Frigessi Di Rattalma, Arnoldo; Thoresen, Magne; Veierød, Marit Bragelien (Journal article; Tidsskriftartikkel, 2020-03-11)
      Ultraviolet radiation (UVR) exposure is a leading cause of skin cancers and an ubiquitous environmental exposure. However, the molecular mechanisms relating UVR exposure to melanoma is not fully understood. We aimed to investigate if lifetime UVR exposure could be robustly associated to DNA methylation (DNAm). We assessed DNAm in whole blood in three data sets (n = 183, 191, and 125) from the Norwegian ...