Blar i forfatter Det helsevitenskapelige fakultet "Pain, Maria Charlene Ronessen"

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    • Comparative exoproteome profiling of an invasive and a commensal Staphylococcus haemolyticus isolate 

      Cavanagh, Jorunn Pauline; Pain, Maria Charlene Ronessen; Askarian, Fatemeh; Bruun, Jack-Ansgar; Urbarova, Ilona; Wai, Sun Nyunt; Schmidt, Frank; Johannessen, Mona (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-22)
      Staphylococcus haemolyticus is a skin commensal emerging as an opportunistic pathogen. Nosocomial isolates of S. haemolyticus are the most antibiotic resistant members of the coagulase negative staphylococci (CoNS), but information about other S. haemolyticus virulence factors is scarce. Bacterial membrane vesicles (MVs) are one mediator of virulence by enabling secretion and long distance delivery ...

    • Comparative exoproteome profiling of an invasive and a commensal Staphylococcus haemolyticus isolate 

      Cavanagh, Jorunn Pauline; Pain, Maria Charlene Ronessen; Askarian, Fatemeh; Bruun, Jack-Ansgar; Urbarova, Ilona; Wai, Sun Nyunt; Schmidt, Frank; Johannessen, Mona (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-22)
      <p><i>Staphylococcus haemolyticus</i> is a skin commensal emerging as an opportunistic pathogen. Nosocomial isolates of <i>S. haemolyticus</i> are the most antibiotic resistant members of the coagulase negative staphylococci (CoNS), but information about other <i>S. haemolyticus</i> virulence factors is scarce. Bacterial membrane vesicles (MVs) are one mediator of virulence by enabling secretion and ...

    • Comparative Genomic Analysis of Staphylococcus haemolyticus Reveals Key to Hospital Adaptation and Pathogenicity 

      Pain, Maria Charlene Ronessen; Hjerde, Erik; Klingenberg, Claus; Cavanagh, Jorunn Pauline (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-10)
      <i>Staphylococcus haemolyticus</i> is a skin commensal gaining increased attention as an emerging pathogen of nosocomial infections. However, knowledge about the transition from a commensal to an invasive lifestyle remains sparse and there is a paucity of studies comparing pathogenicity traits between commensal and clinical isolates. In this study, we used a pan-genomic approach to identify factors ...

    • Exploring the pangenome of Staphylococcus haemolyticus. Colonisation, hospital adaption, pathogenicity and novel species identification 

      Pain, Maria Charlene Ronessen (Doctoral thesis; Doktorgradsavhandling, 2020-04-03)
      Staphylococcus haemolyticus is a ubiquitous bacterium recognised as a significant cause of nosocomial infections. Today it represents one of the most clinically relevant staphylococcal species, hallmarked by its extreme genome plasticity and multiresistant phenotype. Despite its relevance, little is known about its virulence repertoire or how it causes disease. The main objective of this PhD thesis ...